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The map label for this gene is 50085521

Identifier: 50085521

GI number: 50085521

Start: 2401174

End: 2401953

Strand: Reverse

Name: 50085521

Synonym: ACIAD2436

Alternate gene names: NA

Gene position: 2401953-2401174 (Counterclockwise)

Preceding gene: 50085522

Following gene: 50085520

Centisome position: 66.75

GC content: 37.82

Gene sequence:

>780_bases
ATGAAACTTATGGTGAATCATCAGACTCATTACCATTACAGTGAGGTTGCTCGTAATAGTATTCAATATATCAAGATGAT
TCCGCAAAGTTCACCTCATCAACTTGTTCACTACTGGGACATTAGTGTCCCAGGTGAGCGAATTATGAAGCGAGATGCTT
TTGATAATTTATGGATTACTTCTTCACAACGTTTTGATTATCAAAATCTTACGATTATGGCTCAAGGTATTGTTGAATTG
AATCTGCAAAACAGTGGCTGTCATGATTCAGTGGTACTGCCTCACGTATTTTTACAGCCTACACCTGCAACTTTATGTGA
TGCCGAGATGTTGAATTTTGCGCTGGAAATTGTAAAAACTAAAGATGTATCATCCTTAATAAATTTAAGTCAAAAGATAT
TAGAGAGAATAACTTATTCACCGTACTCGACTAATGTGCAAACGACGGCAATAGACGCATTTTATGCAGCTCAAGGCGTA
TGTCAGGATCATGCACACGTGATGATTGCCATGTGTCGAGCATTAAATTTACCCGCACGTTATGTATCTGGGTATTTATA
TGATTATAATTCACCTCATCTCGCGAGCCATGCATGGGCAGAAGTGTATGTAGACCATGAATGGCATTGTTTTGATGTCA
GTAATCAGATTTTTGTACCAAAAACTCATATTTATGTTGCAATAGGGCGTGATTATTTTGATGTTGCTCCAATACGAGGG
ATTCGTGAAAATGGAGGAATTGAAGAAATGATATCAACGGTGCAAGTACTGGCTTGTTGA

Upstream 100 bases:

>100_bases
CGACATTGGATGATGCTTGGCAGACGCTTAAACAGTCACCTGATATAATCAATTTTTATCATTTTGCTGATCAATTACAG
TTAATGTTCGAGGCATCTGC

Downstream 100 bases:

>100_bases
ATGGAAGTGGAAGATATGACCTATTGTTGTGCTTTGCGATTGCAAGATGGTTTGGTATTTATCAGTGACACGCGTACAAA
CGCTGGTGTCGACCAAATCT

Product: transglutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKLMVNHQTHYHYSEVARNSIQYIKMIPQSSPHQLVHYWDISVPGERIMKRDAFDNLWITSSQRFDYQNLTIMAQGIVEL
NLQNSGCHDSVVLPHVFLQPTPATLCDAEMLNFALEIVKTKDVSSLINLSQKILERITYSPYSTNVQTTAIDAFYAAQGV
CQDHAHVMIAMCRALNLPARYVSGYLYDYNSPHLASHAWAEVYVDHEWHCFDVSNQIFVPKTHIYVAIGRDYFDVAPIRG
IRENGGIEEMISTVQVLAC

Sequences:

>Translated_259_residues
MKLMVNHQTHYHYSEVARNSIQYIKMIPQSSPHQLVHYWDISVPGERIMKRDAFDNLWITSSQRFDYQNLTIMAQGIVEL
NLQNSGCHDSVVLPHVFLQPTPATLCDAEMLNFALEIVKTKDVSSLINLSQKILERITYSPYSTNVQTTAIDAFYAAQGV
CQDHAHVMIAMCRALNLPARYVSGYLYDYNSPHLASHAWAEVYVDHEWHCFDVSNQIFVPKTHIYVAIGRDYFDVAPIRG
IRENGGIEEMISTVQVLAC
>Mature_259_residues
MKLMVNHQTHYHYSEVARNSIQYIKMIPQSSPHQLVHYWDISVPGERIMKRDAFDNLWITSSQRFDYQNLTIMAQGIVEL
NLQNSGCHDSVVLPHVFLQPTPATLCDAEMLNFALEIVKTKDVSSLINLSQKILERITYSPYSTNVQTTAIDAFYAAQGV
CQDHAHVMIAMCRALNLPARYVSGYLYDYNSPHLASHAWAEVYVDHEWHCFDVSNQIFVPKTHIYVAIGRDYFDVAPIRG
IRENGGIEEMISTVQVLAC

Specific function: Unknown

COG id: COG1305

COG function: function code E; Transglutaminase-like enzymes, putative cysteine proteases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To M.leprae ML0607 [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013589
- InterPro:   IPR002931 [H]

Pfam domain/function: PF08379 Bact_transglu_N; PF01841 Transglut_core [H]

EC number: NA

Molecular weight: Translated: 29582; Mature: 29582

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLMVNHQTHYHYSEVARNSIQYIKMIPQSSPHQLVHYWDISVPGERIMKRDAFDNLWIT
CEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCHHHHHHHCCCCCEEEE
SSQRFDYQNLTIMAQGIVELNLQNSGCHDSVVLPHVFLQPTPATLCDAEMLNFALEIVKT
CCCCCCCCCEEEEEEEEEEEEECCCCCCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHC
KDVSSLINLSQKILERITYSPYSTNVQTTAIDAFYAAQGVCQDHAHVMIAMCRALNLPAR
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
YVSGYLYDYNSPHLASHAWAEVYVDHEWHCFDVSNQIFVPKTHIYVAIGRDYFDVAPIRG
HHCCEEEECCCCCCCCCCEEEEEECCCEEEEECCCEEEECCEEEEEEECCCCCCCCCCCC
IRENGGIEEMISTVQVLAC
CCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKLMVNHQTHYHYSEVARNSIQYIKMIPQSSPHQLVHYWDISVPGERIMKRDAFDNLWIT
CEEEEECCCCCHHHHHHHHHHHEEEECCCCCCCCEEEEEECCCCHHHHHHHCCCCCEEEE
SSQRFDYQNLTIMAQGIVELNLQNSGCHDSVVLPHVFLQPTPATLCDAEMLNFALEIVKT
CCCCCCCCCEEEEEEEEEEEEECCCCCCCCEECCEEEECCCCCHHHHHHHHHHHHHHHHC
KDVSSLINLSQKILERITYSPYSTNVQTTAIDAFYAAQGVCQDHAHVMIAMCRALNLPAR
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHH
YVSGYLYDYNSPHLASHAWAEVYVDHEWHCFDVSNQIFVPKTHIYVAIGRDYFDVAPIRG
HHCCEEEECCCCCCCCCCEEEEEECCCEEEEECCCEEEECCEEEEEEECCCCCCCCCCCC
IRENGGIEEMISTVQVLAC
CCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]