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The map label for this gene is 50085430

Identifier: 50085430

GI number: 50085430

Start: 2303197

End: 2304708

Strand: Direct

Name: 50085430

Synonym: ACIAD2339

Alternate gene names: NA

Gene position: 2303197-2304708 (Clockwise)

Preceding gene: 50085425

Following gene: 50085431

Centisome position: 64.0

GC content: 37.43

Gene sequence:

>1512_bases
ATGCAACAAGCCACAATAAATGCGACTCAAACAACTAAAATTGCGATTATTGGTGCTGGTTTTGGTGGCTTAGCCATGGC
AATCCGCCTATTACAACATCATATTCGGGATTTTGTAATTTTTGAAAAAGCCCAAGATATTGGGGGAACATGGCGAGAAA
ACCAATATCCTGGTGCAGCCTGTGACGTACAGTCGCATATGTATTCACTTTCTTTTGCGCCAAAAACCAACTGGTCAAAA
CGTTATGCCGAAGCAGGCGAAATTTTTTCTTATATTCAGGATATTTCTGAACAGTTTCAGCTACGTCAGTATTGCAAATT
TGAACACGAAGTAACGCGAGCCGAATATGATGAACAAAATTTTATTTGGAATTTAGAATTTAAAAATCATCCAGCTGTGC
AGGCACAATTTGTAATTTTCGCTTCTGGACCACTGCATGTTCCTCAGATTCCACATATTAAAGGCATCGAAAATTTTAAA
GGAAAAGTTTTTCATTCATCTCAATGGGATCATGGCTACGACCTAAGCAATAAAGTGGTCGCTTCAATTGGTACAGGAGG
AAGTGCAATTCAGTACATTCCAGAAATTGCACAACAAGTTAAGCAATTGTATGTACTGCAACGTACTGCTGCGTGGGTGA
TTCCTCGTGATGAACGTGCATATTCTGGATTAAGTAAGTTACTGTTTAAAAAATCTGACTTTTATCGCCAGATTCATCGT
ATACGTTTGTATTGGAGTAATGAATCGCGAGTAGTTCCGATTGTCCAGCCACAAATTATGAAATACGGCCAAAAGCTTGC
CGAAGCCTTTATCCGCTTTCAAGTGAAGGATAAAACACTTGCAAAGAAACTTACGCCAGATTTCGTGATGGGTTGTAAAC
GTATTTTGATCTCAAATAAATATTTTCCAACCTTTAATCGTAAAAATGTCGAATTAGTGACCGATGGAATTCAGGAAATT
ACAGAAAATGCCATTGTGACCAAAGACGGTAAGCAAAGACATATCGATTGCCTGATTTATGGAACTGGATTTATTACAGA
TCCGCGTATCTATTTGAAGCATTTTGAATGTTTTGGCAAAAATCACCAAGAACTCAAAGAGGCTTGGAAAAATGGACCAG
AAAGTTATTATGGTATAACAACAGCAGGCTTCCCAAATTTATTTCAACTTTTAGGTCCAAATACAGTGCTTGGACATAAT
TCAGTTATTTTTATGATTGAATCCCAAGTTAATTATATTTTACAACTGATTAAGCTGGTCGATACGACCAAAACGCAAGC
AGTAGAAGTTAAAGTACAGGTGCAGAACAACTTTAATGAAACTATTCAAAAACAATTACAAGGCACTGTTTGGCAAGCAG
GTGGATGTGTAAGTTGGTATCAAACCAGTGAAGGTAAGAACTTTTCTCTATGGCCAACTTACACTTGGAAATACTGGCTA
GAAACTCGCAAGATAAATGTCAGTGACTATCATTTTCTAGGTGATATTCAAGCAAAAAAGATTGCGGTCTAA

Upstream 100 bases:

>100_bases
TTAATTGCCGATTCTATCAATTTTCACGGCATTGCAATCATATTATTCTCGCTCTGAACGCTCTAGGATATTGATTAACT
TTTCATCGAGAGTGAATATA

Downstream 100 bases:

>100_bases
ATCTATCAGGTCATAATAAGTAAGTTGCTGACAACTTACTTATTTTATGCAGTCTCTTGTTTTAATATCCCAAATAATTA
TGGCGATTTGCTTAGGCTAT

Product: flavin-binding monooxygenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MQQATINATQTTKIAIIGAGFGGLAMAIRLLQHHIRDFVIFEKAQDIGGTWRENQYPGAACDVQSHMYSLSFAPKTNWSK
RYAEAGEIFSYIQDISEQFQLRQYCKFEHEVTRAEYDEQNFIWNLEFKNHPAVQAQFVIFASGPLHVPQIPHIKGIENFK
GKVFHSSQWDHGYDLSNKVVASIGTGGSAIQYIPEIAQQVKQLYVLQRTAAWVIPRDERAYSGLSKLLFKKSDFYRQIHR
IRLYWSNESRVVPIVQPQIMKYGQKLAEAFIRFQVKDKTLAKKLTPDFVMGCKRILISNKYFPTFNRKNVELVTDGIQEI
TENAIVTKDGKQRHIDCLIYGTGFITDPRIYLKHFECFGKNHQELKEAWKNGPESYYGITTAGFPNLFQLLGPNTVLGHN
SVIFMIESQVNYILQLIKLVDTTKTQAVEVKVQVQNNFNETIQKQLQGTVWQAGGCVSWYQTSEGKNFSLWPTYTWKYWL
ETRKINVSDYHFLGDIQAKKIAV

Sequences:

>Translated_503_residues
MQQATINATQTTKIAIIGAGFGGLAMAIRLLQHHIRDFVIFEKAQDIGGTWRENQYPGAACDVQSHMYSLSFAPKTNWSK
RYAEAGEIFSYIQDISEQFQLRQYCKFEHEVTRAEYDEQNFIWNLEFKNHPAVQAQFVIFASGPLHVPQIPHIKGIENFK
GKVFHSSQWDHGYDLSNKVVASIGTGGSAIQYIPEIAQQVKQLYVLQRTAAWVIPRDERAYSGLSKLLFKKSDFYRQIHR
IRLYWSNESRVVPIVQPQIMKYGQKLAEAFIRFQVKDKTLAKKLTPDFVMGCKRILISNKYFPTFNRKNVELVTDGIQEI
TENAIVTKDGKQRHIDCLIYGTGFITDPRIYLKHFECFGKNHQELKEAWKNGPESYYGITTAGFPNLFQLLGPNTVLGHN
SVIFMIESQVNYILQLIKLVDTTKTQAVEVKVQVQNNFNETIQKQLQGTVWQAGGCVSWYQTSEGKNFSLWPTYTWKYWL
ETRKINVSDYHFLGDIQAKKIAV
>Mature_503_residues
MQQATINATQTTKIAIIGAGFGGLAMAIRLLQHHIRDFVIFEKAQDIGGTWRENQYPGAACDVQSHMYSLSFAPKTNWSK
RYAEAGEIFSYIQDISEQFQLRQYCKFEHEVTRAEYDEQNFIWNLEFKNHPAVQAQFVIFASGPLHVPQIPHIKGIENFK
GKVFHSSQWDHGYDLSNKVVASIGTGGSAIQYIPEIAQQVKQLYVLQRTAAWVIPRDERAYSGLSKLLFKKSDFYRQIHR
IRLYWSNESRVVPIVQPQIMKYGQKLAEAFIRFQVKDKTLAKKLTPDFVMGCKRILISNKYFPTFNRKNVELVTDGIQEI
TENAIVTKDGKQRHIDCLIYGTGFITDPRIYLKHFECFGKNHQELKEAWKNGPESYYGITTAGFPNLFQLLGPNTVLGHN
SVIFMIESQVNYILQLIKLVDTTKTQAVEVKVQVQNNFNETIQKQLQGTVWQAGGCVSWYQTSEGKNFSLWPTYTWKYWL
ETRKINVSDYHFLGDIQAKKIAV

Specific function: Unknown

COG id: COG2072

COG function: function code P; Predicted flavoprotein involved in K+ transport

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-binding monooxygenase family [H]

Homologues:

Organism=Homo sapiens, GI4503757, Length=352, Percent_Identity=24.4318181818182, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI4503759, Length=353, Percent_Identity=24.6458923512748, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI221316674, Length=365, Percent_Identity=25.7534246575342, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI221316672, Length=365, Percent_Identity=25.7534246575342, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI4503755, Length=222, Percent_Identity=25.6756756756757, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI221316678, Length=223, Percent_Identity=26.9058295964126, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25145785, Length=354, Percent_Identity=24.2937853107345, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25150462, Length=226, Percent_Identity=26.9911504424779, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17541300, Length=226, Percent_Identity=29.646017699115, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17555726, Length=352, Percent_Identity=23.5795454545455, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17561948, Length=225, Percent_Identity=25.3333333333333, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19921694, Length=211, Percent_Identity=23.2227488151659, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI19922866, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020946 [H]

Pfam domain/function: PF00743 FMO-like [H]

EC number: NA

Molecular weight: Translated: 57928; Mature: 57928

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQATINATQTTKIAIIGAGFGGLAMAIRLLQHHIRDFVIFEKAQDIGGTWRENQYPGAA
CCCCEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
CDVQSHMYSLSFAPKTNWSKRYAEAGEIFSYIQDISEQFQLRQYCKFEHEVTRAEYDEQN
ECHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FIWNLEFKNHPAVQAQFVIFASGPLHVPQIPHIKGIENFKGKVFHSSQWDHGYDLSNKVV
CEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEE
ASIGTGGSAIQYIPEIAQQVKQLYVLQRTAAWVIPRDERAYSGLSKLLFKKSDFYRQIHR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHE
IRLYWSNESRVVPIVQPQIMKYGQKLAEAFIRFQVKDKTLAKKLTPDFVMGCKRILISNK
EEEEECCCCEEEEECCHHHHHHHHHHHHHHHEEEECCHHHHHHCCHHHHHHHHHHHHCCC
YFPTFNRKNVELVTDGIQEITENAIVTKDGKQRHIDCLIYGTGFITDPRIYLKHFECFGK
CCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCC
NHQELKEAWKNGPESYYGITTAGFPNLFQLLGPNTVLGHNSVIFMIESQVNYILQLIKLV
CHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCEEECCCCEEEEEEHHHHHHHHHHHHH
DTTKTQAVEVKVQVQNNFNETIQKQLQGTVWQAGGCVSWYQTSEGKNFSLWPTYTWKYWL
HCCCCEEEEEEEEECCCHHHHHHHHHCCCEEECCCEEEEEECCCCCCEEECCCCEEEEEE
ETRKINVSDYHFLGDIQAKKIAV
EEEEECCCCEEEECCCCHHEECC
>Mature Secondary Structure
MQQATINATQTTKIAIIGAGFGGLAMAIRLLQHHIRDFVIFEKAQDIGGTWRENQYPGAA
CCCCEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCE
CDVQSHMYSLSFAPKTNWSKRYAEAGEIFSYIQDISEQFQLRQYCKFEHEVTRAEYDEQN
ECHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
FIWNLEFKNHPAVQAQFVIFASGPLHVPQIPHIKGIENFKGKVFHSSQWDHGYDLSNKVV
CEEEEEECCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCEE
ASIGTGGSAIQYIPEIAQQVKQLYVLQRTAAWVIPRDERAYSGLSKLLFKKSDFYRQIHR
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHE
IRLYWSNESRVVPIVQPQIMKYGQKLAEAFIRFQVKDKTLAKKLTPDFVMGCKRILISNK
EEEEECCCCEEEEECCHHHHHHHHHHHHHHHEEEECCHHHHHHCCHHHHHHHHHHHHCCC
YFPTFNRKNVELVTDGIQEITENAIVTKDGKQRHIDCLIYGTGFITDPRIYLKHFECFGK
CCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCC
NHQELKEAWKNGPESYYGITTAGFPNLFQLLGPNTVLGHNSVIFMIESQVNYILQLIKLV
CHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCEEECCCCEEEEEEHHHHHHHHHHHHH
DTTKTQAVEVKVQVQNNFNETIQKQLQGTVWQAGGCVSWYQTSEGKNFSLWPTYTWKYWL
HCCCCEEEEEEEEECCCHHHHHHHHHCCCEEECCCEEEEEECCCCCCEEECCCCEEEEEE
ETRKINVSDYHFLGDIQAKKIAV
EEEEECCCCEEEECCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]