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The map label for this gene is ftsY [H]

Identifier: 50085394

GI number: 50085394

Start: 2267121

End: 2268242

Strand: Reverse

Name: ftsY [H]

Synonym: ACIAD2296

Alternate gene names: 50085394

Gene position: 2268242-2267121 (Counterclockwise)

Preceding gene: 50085397

Following gene: 50085393

Centisome position: 63.03

GC content: 41.27

Gene sequence:

>1122_bases
ATGCAACAGCAATCCAATATGCACAATAAATTCTTGATAGATGCTGATATCGGTGATGACGATGTCACATTGCCTAATTT
ACCAGCAGTTGATGTGCCTATTGTTGAAACCCCTACAGCCACATCTACGACTGAAAGCCCGTCAGTTGTATCACAACAAA
AAACTGAAACAGAACAAGAGTCTGAATCAGAGAATAAAAGTGGTTTCTTTAGCCGCATGAAACAAGGCTTGACTAAAACC
CGCCGTAACTTAGCAGATGGTATGGTCAACATTCTGATTGGTGGTAAAGAAATTGATGACGAACTGCTAGAAGAAGTTGA
AGAACAATTACTTGTCGCGGATATTGGTGTCGATGCAACCAAAACGATTATTACCAATCTCACCGAGCGTACAGCACGTG
GTGACCTGATTTATTCACATTCTTTATATAAGGCGCTACAGGAAGAATTAGTTGCACTTTTGGCACCTCGTGTTAAACCG
TTACATATCGATCCAAATAAGACGCCATATGTAATTTTAATGGTAGGGGTAAATGGCGTAGGAAAAACGACGACCATTGG
CAAACTTGCAAAGCGTCTTCAGGGTGAAGGCAAAAAAGTGATGCTTGCAGCAGGGGATACCTTTCGTGCTGCGGCTACCG
AGCAATTGCAAATCTGGGGGGAGCGCAACAATATTTCAGTAGTTGCACAAGGTCATGGTGCAGATAGTGCTTCAGTAATT
TTTGATGCATTTGAAAGTGCGCGTGCAAAAGGGATTGATGTATTGATCGCTGATACTGCAGGTCGTTTACATAATAAAAG
TAACTTGATGGAAGAACTTAAAAAAGTAAAACGTGTCATGCAAAAAATTGATGCAACAGCCCCTCATGAAATTATGTTGG
TGGTTGATGCTGGAACGGGTCAAAATGCGATTAATCAGGTACAGGAGTTTGATCAGGCTGTAGGATTAACGGGTATTACC
ATTACCAAACTTGATGGAACCGCAAAAGGTGGTGTTCTGTTTAATATTGCAAGTCGTACACATGTACCAATTCGCTTTAT
TGGCGTAGGTGAAAAGATTGATGACTTACGTCCTTTCTCTGCCAAATCTTTTGTTGCTGCCCTGTTCGAAACAGACAAAT
AA

Upstream 100 bases:

>100_bases
TTTTAGTTATGAATATTTTGAGTGAGATATATTGTCGGGAATCGACATCAATCTATGTTAAACTCTGGCTTTTAACCCGC
TGCTTTTCAAGGGAATCGGC

Downstream 100 bases:

>100_bases
AATTTGATTTCAGAATACATATAAAACTCCACTTAGTGTGGAGTTTTTGTTTTAAAACCTTAAAAACGTAAAACTGTTCT
AAAAATAAAACGATATGTCG

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MQQQSNMHNKFLIDADIGDDDVTLPNLPAVDVPIVETPTATSTTESPSVVSQQKTETEQESESENKSGFFSRMKQGLTKT
RRNLADGMVNILIGGKEIDDELLEEVEEQLLVADIGVDATKTIITNLTERTARGDLIYSHSLYKALQEELVALLAPRVKP
LHIDPNKTPYVILMVGVNGVGKTTTIGKLAKRLQGEGKKVMLAAGDTFRAAATEQLQIWGERNNISVVAQGHGADSASVI
FDAFESARAKGIDVLIADTAGRLHNKSNLMEELKKVKRVMQKIDATAPHEIMLVVDAGTGQNAINQVQEFDQAVGLTGIT
ITKLDGTAKGGVLFNIASRTHVPIRFIGVGEKIDDLRPFSAKSFVAALFETDK

Sequences:

>Translated_373_residues
MQQQSNMHNKFLIDADIGDDDVTLPNLPAVDVPIVETPTATSTTESPSVVSQQKTETEQESESENKSGFFSRMKQGLTKT
RRNLADGMVNILIGGKEIDDELLEEVEEQLLVADIGVDATKTIITNLTERTARGDLIYSHSLYKALQEELVALLAPRVKP
LHIDPNKTPYVILMVGVNGVGKTTTIGKLAKRLQGEGKKVMLAAGDTFRAAATEQLQIWGERNNISVVAQGHGADSASVI
FDAFESARAKGIDVLIADTAGRLHNKSNLMEELKKVKRVMQKIDATAPHEIMLVVDAGTGQNAINQVQEFDQAVGLTGIT
ITKLDGTAKGGVLFNIASRTHVPIRFIGVGEKIDDLRPFSAKSFVAALFETDK
>Mature_373_residues
MQQQSNMHNKFLIDADIGDDDVTLPNLPAVDVPIVETPTATSTTESPSVVSQQKTETEQESESENKSGFFSRMKQGLTKT
RRNLADGMVNILIGGKEIDDELLEEVEEQLLVADIGVDATKTIITNLTERTARGDLIYSHSLYKALQEELVALLAPRVKP
LHIDPNKTPYVILMVGVNGVGKTTTIGKLAKRLQGEGKKVMLAAGDTFRAAATEQLQIWGERNNISVVAQGHGADSASVI
FDAFESARAKGIDVLIADTAGRLHNKSNLMEELKKVKRVMQKIDATAPHEIMLVVDAGTGQNAINQVQEFDQAVGLTGIT
ITKLDGTAKGGVLFNIASRTHVPIRFIGVGEKIDDLRPFSAKSFVAALFETDK

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI295424842, Length=322, Percent_Identity=31.9875776397516, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI23308697, Length=322, Percent_Identity=31.9875776397516, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI4507215, Length=302, Percent_Identity=33.4437086092715, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI226371618, Length=231, Percent_Identity=35.9307359307359, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI89061728, Length=125, Percent_Identity=36, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1789874, Length=323, Percent_Identity=61.9195046439629, Blast_Score=390, Evalue=1e-110,
Organism=Escherichia coli, GI1788963, Length=299, Percent_Identity=34.1137123745819, Blast_Score=158, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=275, Percent_Identity=32.3636363636364, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193206261, Length=315, Percent_Identity=31.1111111111111, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325345, Length=199, Percent_Identity=36.1809045226131, Blast_Score=127, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6320498, Length=229, Percent_Identity=32.7510917030568, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17647949, Length=274, Percent_Identity=34.3065693430657, Blast_Score=140, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24641198, Length=257, Percent_Identity=30.7392996108949, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 40430; Mature: 40430

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQSNMHNKFLIDADIGDDDVTLPNLPAVDVPIVETPTATSTTESPSVVSQQKTETEQE
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHH
SESENKSGFFSRMKQGLTKTRRNLADGMVNILIGGKEIDDELLEEVEEQLLVADIGVDAT
HHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHH
KTIITNLTERTARGDLIYSHSLYKALQEELVALLAPRVKPLHIDPNKTPYVILMVGVNGV
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCC
GKTTTIGKLAKRLQGEGKKVMLAAGDTFRAAATEQLQIWGERNNISVVAQGHGADSASVI
CCCHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCEEEEEECCCCEEEEEECCCCCHHHHH
FDAFESARAKGIDVLIADTAGRLHNKSNLMEELKKVKRVMQKIDATAPHEIMLVVDAGTG
HHHHHHHHCCCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
QNAINQVQEFDQAVGLTGITITKLDGTAKGGVLFNIASRTHVPIRFIGVGEKIDDLRPFS
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCEEEEECCCCHHHCCCCC
AKSFVAALFETDK
HHHHHHHHHHCCC
>Mature Secondary Structure
MQQQSNMHNKFLIDADIGDDDVTLPNLPAVDVPIVETPTATSTTESPSVVSQQKTETEQE
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHH
SESENKSGFFSRMKQGLTKTRRNLADGMVNILIGGKEIDDELLEEVEEQLLVADIGVDAT
HHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHH
KTIITNLTERTARGDLIYSHSLYKALQEELVALLAPRVKPLHIDPNKTPYVILMVGVNGV
HHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCC
GKTTTIGKLAKRLQGEGKKVMLAAGDTFRAAATEQLQIWGERNNISVVAQGHGADSASVI
CCCHHHHHHHHHHCCCCCEEEEEECCCHHHHCCCEEEEEECCCCEEEEEECCCCCHHHHH
FDAFESARAKGIDVLIADTAGRLHNKSNLMEELKKVKRVMQKIDATAPHEIMLVVDAGTG
HHHHHHHHCCCCEEEEECCCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
QNAINQVQEFDQAVGLTGITITKLDGTAKGGVLFNIASRTHVPIRFIGVGEKIDDLRPFS
HHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEECCCCCCCEEEEECCCCHHHCCCCC
AKSFVAALFETDK
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]