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The map label for this gene is tsf

Identifier: 50085371

GI number: 50085371

Start: 2238425

End: 2239300

Strand: Reverse

Name: tsf

Synonym: ACIAD2268

Alternate gene names: 50085371

Gene position: 2239300-2238425 (Counterclockwise)

Preceding gene: 50085372

Following gene: 50085370

Centisome position: 62.23

GC content: 39.73

Gene sequence:

>876_bases
ATGACTGCAATTACTGCAAGCATGGTAAAAGAATTACGTGACCGTACTGGTCTTGCAATGATGGAATGCAAAAAAGCATT
AACAGAAGCGAATGGTGATATCGAGCTTGCGATTGATAACCTTCGTAAATCTGGTCAGGCAAAAGCTGCTAAAAAAGCAG
GTAACATTGCAGCTGACGGTGCAATTACAATCGTTCAAGACGGTAATAAAGCAGTATTGGTAGAAGTTAACTGTCAAACT
GACTTCGTTGCAAAAGACGAAAACTTCTCTAACTTCTCTAATGCAGTTGCTAAAGCAATTCTTGCATCTGGTGAAACAGA
TGCTGAAAAAGTTGCTGAACTTAAATTAGAAGATGGTCAATCTGTTGAAGAAGCGCGTATTGCTCTTGTTCAAAAAATTG
GTGAAAACATCCAAGTTCGTCGTGCAAAAATCGTTGAAGGTGAAAACCTTGCTGTTTACAAACACGGTCTTCGTATTGGT
GTAGTTGTGTCTTATACAGGTAGTGCTGAAACTGGTAAAGGTATTGCAATGCACGTTGCTGCGTTTAATCCAGTTGCAGT
AAGTGCTGAAGCAGTACCAGCAGACCTAGTTGCTAAAGAGAAAGAAATTGCTGAAGCAAAAGCAATTGAATCTGGCAAAC
CTGCAAACATTGTGGAGAAAATGGTGTCTGGTTCAGTTGAAAAATACTTGAACGAAGTTGCACTTGATCGTCAAATGTAC
GTGATCGACAATGACAAGAAAGTTGCTGATGTATTAAAAGCTACAGCAACTAACATTGTTGAATTTGTACGTTTCGAAGT
GGGTGAAGGTATTGAGAAAAAAGCAGAAATGAGCTTCGCTGAAGAAGTTGCTGCTGCTCAAGCCGCTGCAAAATAA

Upstream 100 bases:

>100_bases
TAACAGTGGCAAATTAAGCGTCGAGAAAGCAAACGGCCCAGAGTTTCCTTGGGCCGTTTTTTTTAAAAAGATTTATTTTC
TACCTATTTAGGAGAACAAC

Downstream 100 bases:

>100_bases
TTGATTATTTTGTAAAAAGCTCCTTCGGGAGCTTTTTTTATATCGTTTGATTAGGGCGTATTGAATGAACAGAACGGGAT
TGTATTCAGCAATAGCGGTT

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADGAITIVQDGNKAVLVEVNCQT
DFVAKDENFSNFSNAVAKAILASGETDAEKVAELKLEDGQSVEEARIALVQKIGENIQVRRAKIVEGENLAVYKHGLRIG
VVVSYTGSAETGKGIAMHVAAFNPVAVSAEAVPADLVAKEKEIAEAKAIESGKPANIVEKMVSGSVEKYLNEVALDRQMY
VIDNDKKVADVLKATATNIVEFVRFEVGEGIEKKAEMSFAEEVAAAQAAAK

Sequences:

>Translated_291_residues
MTAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADGAITIVQDGNKAVLVEVNCQT
DFVAKDENFSNFSNAVAKAILASGETDAEKVAELKLEDGQSVEEARIALVQKIGENIQVRRAKIVEGENLAVYKHGLRIG
VVVSYTGSAETGKGIAMHVAAFNPVAVSAEAVPADLVAKEKEIAEAKAIESGKPANIVEKMVSGSVEKYLNEVALDRQMY
VIDNDKKVADVLKATATNIVEFVRFEVGEGIEKKAEMSFAEEVAAAQAAAK
>Mature_290_residues
TAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADGAITIVQDGNKAVLVEVNCQTD
FVAKDENFSNFSNAVAKAILASGETDAEKVAELKLEDGQSVEEARIALVQKIGENIQVRRAKIVEGENLAVYKHGLRIGV
VVSYTGSAETGKGIAMHVAAFNPVAVSAEAVPADLVAKEKEIAEAKAIESGKPANIVEKMVSGSVEKYLNEVALDRQMYV
IDNDKKVADVLKATATNIVEFVRFEVGEGIEKKAEMSFAEEVAAAQAAAK

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family

Homologues:

Organism=Homo sapiens, GI171846268, Length=304, Percent_Identity=26.9736842105263, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI291084500, Length=325, Percent_Identity=25.2307692307692, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI291084498, Length=109, Percent_Identity=37.6146788990826, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI291084502, Length=109, Percent_Identity=37.6146788990826, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1786366, Length=286, Percent_Identity=54.1958041958042, Blast_Score=271, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI17561440, Length=294, Percent_Identity=28.9115646258503, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI19921466, Length=289, Percent_Identity=30.1038062283737, Blast_Score=113, Evalue=1e-25,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): EFTS_ACIAD (Q6FA54)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046881.1
- ProteinModelPortal:   Q6FA54
- SMR:   Q6FA54
- STRING:   Q6FA54
- GeneID:   2880790
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD2268
- NMPDR:   fig|62977.3.peg.2168
- eggNOG:   COG0264
- HOGENOM:   HBG713289
- OMA:   YLHGTRI
- PhylomeDB:   Q6FA54
- ProtClustDB:   PRK09377
- BioCyc:   ASP62977:ACIAD2268-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00050
- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449
- Gene3D:   G3DSA:3.30.479.20
- PANTHER:   PTHR11741
- TIGRFAMs:   TIGR00116

Pfam domain/function: PF00889 EF_TS; PF00627 UBA; SSF54713 EF_TS; SSF46934 UBA_like

EC number: NA

Molecular weight: Translated: 30883; Mature: 30751

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS01126 EF_TS_1; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADG
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHCCCEECCC
AITIVQDGNKAVLVEVNCQTDFVAKDENFSNFSNAVAKAILASGETDAEKVAELKLEDGQ
EEEEEECCCEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
SVEEARIALVQKIGENIQVRRAKIVEGENLAVYKHGLRIGVVVSYTGSAETGKGIAMHVA
CHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCEEEEEEEECCCCCCCCCEEEEEE
AFNPVAVSAEAVPADLVAKEKEIAEAKAIESGKPANIVEKMVSGSVEKYLNEVALDRQMY
ECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCEEE
VIDNDKKVADVLKATATNIVEFVRFEVGEGIEKKAEMSFAEEVAAAQAAAK
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAITASMVKELRDRTGLAMMECKKALTEANGDIELAIDNLRKSGQAKAAKKAGNIAADG
CCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEHHHHCCCCHHHHHHCCCEECCC
AITIVQDGNKAVLVEVNCQTDFVAKDENFSNFSNAVAKAILASGETDAEKVAELKLEDGQ
EEEEEECCCEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
SVEEARIALVQKIGENIQVRRAKIVEGENLAVYKHGLRIGVVVSYTGSAETGKGIAMHVA
CHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEECCCEEEEEEEECCCCCCCCCEEEEEE
AFNPVAVSAEAVPADLVAKEKEIAEAKAIESGKPANIVEKMVSGSVEKYLNEVALDRQMY
ECCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCEEE
VIDNDKKVADVLKATATNIVEFVRFEVGEGIEKKAEMSFAEEVAAAQAAAK
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA