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The map label for this gene is rodA [H]

Identifier: 50085366

GI number: 50085366

Start: 2233917

End: 2234996

Strand: Direct

Name: rodA [H]

Synonym: ACIAD2263

Alternate gene names: 50085366

Gene position: 2233917-2234996 (Clockwise)

Preceding gene: 50085365

Following gene: 50085367

Centisome position: 62.08

GC content: 41.94

Gene sequence:

>1080_bases
ATGTTGCCATCGCGATGGCAACGACTACATATTGATCCTTGGCTCTGCTCTTTTCTGCTTTTAAATGCCTGCCTTGGCCT
GACTGTTCTTTATAGCGCATCGGCACAAGACGTTGGGCTTGTTTCAAAGCAAGCCATGAGTTTTGGAATCGGATTTATTG
TCATGCTTGGGCTTGCACAAATTCCACCCAAGGTCTATCAGGCATTTTCTCCCTATTTTTATTTGATCGCATTGTTTGCC
TTAGTTGCCGTAAAAGTTTTTGGTGAGATCCGAATGGGTGCACAGCGCTGGATTGATATTCCAGGCTTCGGTAGTGTCCA
GCCCAGCGAATTTATGAAAATTGGTATGCCCATGATGGTCGCTTGGTTTTTATCCAGAAAACCGCTTCCACCGAGTCTGA
TCAATGTCCTAGGCTCTCTCCTTCTCATTGGTATTCCTTTTATTTTAATTGCAGAACAGCCTGACTTAGGTACTTCACTA
TTGGTTTTGGCCAGTGGTGTATTTGTGCTTTTTCTGAGTGGTCTTTCATGGAAAATCATTGGTGCAGCCGCTGCGGGAGC
AGGCTTACTTATTCCAGTTGCCTGGGAATTTCTATTACATGATTATCAGCGTCAGCGTGTACTTACCTTACTTAACCCTG
AGGCAGATGCACTTGGAACAGGCTGGAATATTATTCAATCAAAAACGGCGATTGGCTCTGGGGGTTTTTCAGGAAAAGGT
TTTTTAGAAGGTACCCAGTCACATTTGCACTTTTTGCCAGAAGGCCATACCGATTTTATTATTGCTGCTTACTCAGAAGA
ATTTGGACTGATTGGCGTCACTATTCTGATCATATTATATTTTGCAATTATTTTTAGAACGTTTCAGATTGGACTGCAAT
GTTTCCACAACTATGGACGTCTTGTTGCAGGATCGTTTGGTTTGTCTTTTTTTGTTTATGTATTTGTAAATGCTGGAATG
GTTAGTGGTATTTTACCAGTAGTAGGTGTGCCATTACCCTTCATGAGCTACGGTGGTACTGCAATCATTACTTTAATGGC
TACTTTTGGATTGGTCATGTCAATTCATACACATCGATAA

Upstream 100 bases:

>100_bases
CATGCGCCATGCATTGATTGATCCTTTGTAAAACCTTATGTCTCCAAGCTCTCAATATAAATTTTTGCGTCAGGCACCTC
GTGATGGTTTAAGTACTGCG

Downstream 100 bases:

>100_bases
TTATATTTTTATTTTTGATTCAGGGACTAATAACATTATGTTGAATTTGGTGCTAAACAAACCATTTAAACAACTTCTAA
TCATGAGCAGTTTATTTATC

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MLPSRWQRLHIDPWLCSFLLLNACLGLTVLYSASAQDVGLVSKQAMSFGIGFIVMLGLAQIPPKVYQAFSPYFYLIALFA
LVAVKVFGEIRMGAQRWIDIPGFGSVQPSEFMKIGMPMMVAWFLSRKPLPPSLINVLGSLLLIGIPFILIAEQPDLGTSL
LVLASGVFVLFLSGLSWKIIGAAAAGAGLLIPVAWEFLLHDYQRQRVLTLLNPEADALGTGWNIIQSKTAIGSGGFSGKG
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVTILIILYFAIIFRTFQIGLQCFHNYGRLVAGSFGLSFFVYVFVNAGM
VSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR

Sequences:

>Translated_359_residues
MLPSRWQRLHIDPWLCSFLLLNACLGLTVLYSASAQDVGLVSKQAMSFGIGFIVMLGLAQIPPKVYQAFSPYFYLIALFA
LVAVKVFGEIRMGAQRWIDIPGFGSVQPSEFMKIGMPMMVAWFLSRKPLPPSLINVLGSLLLIGIPFILIAEQPDLGTSL
LVLASGVFVLFLSGLSWKIIGAAAAGAGLLIPVAWEFLLHDYQRQRVLTLLNPEADALGTGWNIIQSKTAIGSGGFSGKG
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVTILIILYFAIIFRTFQIGLQCFHNYGRLVAGSFGLSFFVYVFVNAGM
VSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR
>Mature_359_residues
MLPSRWQRLHIDPWLCSFLLLNACLGLTVLYSASAQDVGLVSKQAMSFGIGFIVMLGLAQIPPKVYQAFSPYFYLIALFA
LVAVKVFGEIRMGAQRWIDIPGFGSVQPSEFMKIGMPMMVAWFLSRKPLPPSLINVLGSLLLIGIPFILIAEQPDLGTSL
LVLASGVFVLFLSGLSWKIIGAAAAGAGLLIPVAWEFLLHDYQRQRVLTLLNPEADALGTGWNIIQSKTAIGSGGFSGKG
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVTILIILYFAIIFRTFQIGLQCFHNYGRLVAGSFGLSFFVYVFVNAGM
VSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=354, Percent_Identity=55.3672316384181, Blast_Score=368, Evalue=1e-103,
Organism=Escherichia coli, GI1786277, Length=316, Percent_Identity=32.5949367088608, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 39029; Mature: 39029

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPSRWQRLHIDPWLCSFLLLNACLGLTVLYSASAQDVGLVSKQAMSFGIGFIVMLGLAQ
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPPKVYQAFSPYFYLIALFALVAVKVFGEIRMGAQRWIDIPGFGSVQPSEFMKIGMPMMV
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCHHHHHHHCHHHHH
AWFLSRKPLPPSLINVLGSLLLIGIPFILIAEQPDLGTSLLVLASGVFVLFLSGLSWKII
HHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEE
GAAAAGAGLLIPVAWEFLLHDYQRQRVLTLLNPEADALGTGWNIIQSKTAIGSGGFSGKG
EHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVTILIILYFAIIFRTFQIGLQCFHNYGR
CCCCCHHHHEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
LVAGSFGLSFFVYVFVNAGMVSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLPSRWQRLHIDPWLCSFLLLNACLGLTVLYSASAQDVGLVSKQAMSFGIGFIVMLGLAQ
CCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IPPKVYQAFSPYFYLIALFALVAVKVFGEIRMGAQRWIDIPGFGSVQPSEFMKIGMPMMV
CCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHHEECCCCCCCCCHHHHHHHCHHHHH
AWFLSRKPLPPSLINVLGSLLLIGIPFILIAEQPDLGTSLLVLASGVFVLFLSGLSWKII
HHHHHCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEE
GAAAAGAGLLIPVAWEFLLHDYQRQRVLTLLNPEADALGTGWNIIQSKTAIGSGGFSGKG
EHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCCC
FLEGTQSHLHFLPEGHTDFIIAAYSEEFGLIGVTILIILYFAIIFRTFQIGLQCFHNYGR
CCCCCHHHHEECCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
LVAGSFGLSFFVYVFVNAGMVSGILPVVGVPLPFMSYGGTAIITLMATFGLVMSIHTHR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]