Click here to switch to the map view.

The map label for this gene is fpr [H]

Identifier: 50085349

GI number: 50085349

Start: 2214826

End: 2215605

Strand: Direct

Name: fpr [H]

Synonym: ACIAD2244

Alternate gene names: 50085349

Gene position: 2214826-2215605 (Clockwise)

Preceding gene: 50085347

Following gene: 50085351

Centisome position: 61.55

GC content: 38.59

Gene sequence:

>780_bases
ATGGCTGCTTTTAATGTTGAACGCATTACCCATGTTCACCACTGGAATGACACTCTGTTTAGTTTTAAAACCACGCGCGA
TGTCGCATTACGTTTTAAGAATGGTCAGTTTGTAATGATCGGGCTTGAGGTCAATGGTAAGCCATTAATGCGTGCTTATT
CAATTGCCAGCGCTAACTATGAAGAAGAACTTGAGTTTTTCTCAATCAAAGTGCAAGAAGGCCCATTAACCTCGATTTTA
CAGAAAGTACAAGTGGGTGATGAAATTCTAATTTCTAAAAAGCCTACAGGTACTTTGGTTCATGATGATTTGAATCCAGG
TAAAAACCTATATTTCCTTTCTTCTGGAACAGGTCTTGCACCATTTTTATCATTAATTCGTGATCCTGAAACTTACGAAA
AATTTGAAAAAGTGATTTTGGTACATGGTACACGCTGGATTAGCGAGTTGGCTTATCAAGATTTGATTTTGAATGAATTA
CCAAACAATGAATGGTTTGAAGAACTCGATATCAAAAATAAATTAATCTATTACCCAACAGTTACCCGCGAACCTTTTGA
AAATGAAGGTCGTGTAACGACTGCCATTGAAACTGGTGCGTTATTTGAAAAAATTGGTTTACCGCCATTTAATCCAGAAA
CTGACCGTGCGATGCTTTGCGGTAGCCCACATTTCTTGACAGATGTGGCAGCACTTTTGGATAAAGCGGGTTTAAAAGAA
TCGCCACGTATGGGTGTTCTTGGTGACTACGTGATCGAACGTGCTTTCGTAGAAAAGTAA

Upstream 100 bases:

>100_bases
CACTTTTTCTTATAAACACAATTAAATATATTCAGTTTATCGGGAAAGATTTTAGATTAGAATAGCAATCTGTTTCTTTT
GATCGTGATTGAGATCTTTA

Downstream 100 bases:

>100_bases
GAAATTACCGTTTAAAAAAACCGAGAATAGTTTCTCGGTTTTTTTAAATTCAATTATTTTTGAAGTTTTTTATTCTGAAA
AATATCTATTAAATTAGGTG

Product: ferredoxin--NADP+ reductase

Products: NA

Alternate protein names: FNR; Protein X [H]

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MAAFNVERITHVHHWNDTLFSFKTTRDVALRFKNGQFVMIGLEVNGKPLMRAYSIASANYEEELEFFSIKVQEGPLTSIL
QKVQVGDEILISKKPTGTLVHDDLNPGKNLYFLSSGTGLAPFLSLIRDPETYEKFEKVILVHGTRWISELAYQDLILNEL
PNNEWFEELDIKNKLIYYPTVTREPFENEGRVTTAIETGALFEKIGLPPFNPETDRAMLCGSPHFLTDVAALLDKAGLKE
SPRMGVLGDYVIERAFVEK

Sequences:

>Translated_259_residues
MAAFNVERITHVHHWNDTLFSFKTTRDVALRFKNGQFVMIGLEVNGKPLMRAYSIASANYEEELEFFSIKVQEGPLTSIL
QKVQVGDEILISKKPTGTLVHDDLNPGKNLYFLSSGTGLAPFLSLIRDPETYEKFEKVILVHGTRWISELAYQDLILNEL
PNNEWFEELDIKNKLIYYPTVTREPFENEGRVTTAIETGALFEKIGLPPFNPETDRAMLCGSPHFLTDVAALLDKAGLKE
SPRMGVLGDYVIERAFVEK
>Mature_258_residues
AAFNVERITHVHHWNDTLFSFKTTRDVALRFKNGQFVMIGLEVNGKPLMRAYSIASANYEEELEFFSIKVQEGPLTSILQ
KVQVGDEILISKKPTGTLVHDDLNPGKNLYFLSSGTGLAPFLSLIRDPETYEKFEKVILVHGTRWISELAYQDLILNELP
NNEWFEELDIKNKLIYYPTVTREPFENEGRVTTAIETGALFEKIGLPPFNPETDRAMLCGSPHFLTDVAALLDKAGLKES
PRMGVLGDYVIERAFVEK

Specific function: Transports Electrons Between Flavodoxin Or Ferredoxin And NADPH. Involved In The Reductive Activation Of Cobalamin- Independent Methionine Synthase, Pyruvate Formate Lyase And Anaerobic Ribonucleotide Reductase. Also Protects Against Superoxide Radicals

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790359, Length=235, Percent_Identity=34.0425531914894, Blast_Score=134, Evalue=6e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 29371; Mature: 29240

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFNVERITHVHHWNDTLFSFKTTRDVALRFKNGQFVMIGLEVNGKPLMRAYSIASANY
CCCCCHHHHHEEECCCCCEEEEECCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHCCCC
EEELEFFSIKVQEGPLTSILQKVQVGDEILISKKPTGTLVHDDLNPGKNLYFLSSGTGLA
HHCEEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCEEEEECCCCHH
PFLSLIRDPETYEKFEKVILVHGTRWISELAYQDLILNELPNNEWFEELDIKNKLIYYPT
HHHHHHCCCHHHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEC
VTREPFENEGRVTTAIETGALFEKIGLPPFNPETDRAMLCGSPHFLTDVAALLDKAGLKE
CCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
SPRMGVLGDYVIERAFVEK
CCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
AAFNVERITHVHHWNDTLFSFKTTRDVALRFKNGQFVMIGLEVNGKPLMRAYSIASANY
CCCCHHHHHEEECCCCCEEEEECCEEEEEEEECCCEEEEEEEECCCCHHHHHHHHCCCC
EEELEFFSIKVQEGPLTSILQKVQVGDEILISKKPTGTLVHDDLNPGKNLYFLSSGTGLA
HHCEEEEEEEECCCCHHHHHHHHHCCCEEEEECCCCCCEEECCCCCCCCEEEEECCCCHH
PFLSLIRDPETYEKFEKVILVHGTRWISELAYQDLILNELPNNEWFEELDIKNKLIYYPT
HHHHHHCCCHHHHHHHHEEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCEEEEEEC
VTREPFENEGRVTTAIETGALFEKIGLPPFNPETDRAMLCGSPHFLTDVAALLDKAGLKE
CCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHHHHCCCCC
SPRMGVLGDYVIERAFVEK
CCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7673160; 8034707; 9865948 [H]