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The map label for this gene is ydcR [H]

Identifier: 50085166

GI number: 50085166

Start: 2021646

End: 2023067

Strand: Direct

Name: ydcR [H]

Synonym: ACIAD2032

Alternate gene names: 50085166

Gene position: 2021646-2023067 (Clockwise)

Preceding gene: 50085162

Following gene: 50085169

Centisome position: 56.18

GC content: 37.27

Gene sequence:

>1422_bases
TTGCCCATGTATAAGTCAGACCAATTAGCGCATCAACTCAAATCTTTAATTGAAAAAAATATCTGGAAAGCACATACCAA
ACTTCCTTCACTTCGTGAGCAGGTTGAAAGTTCTGGGTTTAGTTTAATGACTGTCATGAATGCTTATCAAAAGCTGGAAG
CTCAGGGCCTCATCTATTCTAAAGAAAAATCAGGTTATTTTGTTGCAGAACAAACGAAACCTGCTCTAGATTCTGCTAGC
ACACTCGCTCCAAAAATTGAAATTAACTCGTCTGTTTTTAAATATCTCAAATCGATTCAGACGCCTAATCTAGTTTCACT
CGGTTCTGCCTTTCCTGATAGTGAATTATTATTGCCGATCAAATTACGTCAGATTGTAAGCCAGCTTGCGCGGTATCCAA
AAAGTTATGATCAGACCACCAATCTTCCACCTGGTAATTTGGCTTTAAGAAAAATTATTGCCCAGCGCTATTGTATGCAA
GGAATTCCGACACAAGCCGATGATATTGTCATTACTTCAGGGGGCTTAGATGCATTAAACCTCTCATTACAGGCACTCAC
TCAACCTGGCGATTATATTGTGTTGCAGCAGACAACTTTTTACGGCGCTTGGCAAGCAGCGGAGCGATTAGGATTAAAAG
TGATTACGGTGCCTGAACATGCACATTGCGGTATAGACGTAGATGCTTTTGAACAGTTGATTTTGCACTACCCTGTAAAA
GTATGCTGGATGATGTTTAATGCACACAATCCTTTAGGATTTACAGTATCTGAAGAAATCAAATTTAAGATCGCAAAATT
ACTGCATCAACATCATATTCATCTTATTGAAGACGATGTATACGAAGAACTTTTTGATGGCTTAAATAAACCACTTCCCA
TGAAATATTATGATCAGAATAATCTGGTTATGCATTGTTCCTCATTCTCTAAAACACTGGGTGCAGGCTTTCGTGTTGGC
TGGGTGTATGCAGGTAAATACTCTGAACATATTCAACACTTGCAACTTATGAGTACCATTTCAGCGAATACCCTTGTTCA
AAATGCACTGGTTGAATTTTTATCTAGCCATCATTATGAAAAACATTTGAGAAGTCTGAGATTGAAGCTTAAAAAAAATA
AAAAACGCTTTTATCACTATCTTAAGCAGAATCTGCCAACACAATGCCGTATTCACTATGAATTAGGTGGTTATTTTTTA
TGTATTATGCTTCCAGAACAAGCCAGTAGTGAAGAAATCTACAAAACATTGCTAAACCAAAATATTGCTGTAGCACCAAG
CATATTATTTAACTACTCTCAGCAGCATCAACAGTTTATTCGGATCAACTGCTCATTTGACTGGAGCAATCATATTCAAT
CTGCGTTGGATGTCCTGACTATTACACTCAAACAATTATCTAATGCAAAGCTTGAAACATAA

Upstream 100 bases:

>100_bases
TATTTCTTAATCTCAATTGATAAATTATTAATAGATATAGCTAGTTGAGGCCTTACTTTTCAATTAGATTAACTCGATAC
AATCATTTTATTTTTGTGCT

Downstream 100 bases:

>100_bases
ATACTCACTTAAAGTAATACACAATATTTATGCAACAAAAAATGGCTTGGGTAACGATACACCAAGCCATTTTTTTAACT
CACTTTTAGATGCTTACTTT

Product: bifunctional transcriptional regulator/ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 472

Protein sequence:

>473_residues
MPMYKSDQLAHQLKSLIEKNIWKAHTKLPSLREQVESSGFSLMTVMNAYQKLEAQGLIYSKEKSGYFVAEQTKPALDSAS
TLAPKIEINSSVFKYLKSIQTPNLVSLGSAFPDSELLLPIKLRQIVSQLARYPKSYDQTTNLPPGNLALRKIIAQRYCMQ
GIPTQADDIVITSGGLDALNLSLQALTQPGDYIVLQQTTFYGAWQAAERLGLKVITVPEHAHCGIDVDAFEQLILHYPVK
VCWMMFNAHNPLGFTVSEEIKFKIAKLLHQHHIHLIEDDVYEELFDGLNKPLPMKYYDQNNLVMHCSSFSKTLGAGFRVG
WVYAGKYSEHIQHLQLMSTISANTLVQNALVEFLSSHHYEKHLRSLRLKLKKNKKRFYHYLKQNLPTQCRIHYELGGYFL
CIMLPEQASSEEIYKTLLNQNIAVAPSILFNYSQQHQQFIRINCSFDWSNHIQSALDVLTITLKQLSNAKLET

Sequences:

>Translated_473_residues
MPMYKSDQLAHQLKSLIEKNIWKAHTKLPSLREQVESSGFSLMTVMNAYQKLEAQGLIYSKEKSGYFVAEQTKPALDSAS
TLAPKIEINSSVFKYLKSIQTPNLVSLGSAFPDSELLLPIKLRQIVSQLARYPKSYDQTTNLPPGNLALRKIIAQRYCMQ
GIPTQADDIVITSGGLDALNLSLQALTQPGDYIVLQQTTFYGAWQAAERLGLKVITVPEHAHCGIDVDAFEQLILHYPVK
VCWMMFNAHNPLGFTVSEEIKFKIAKLLHQHHIHLIEDDVYEELFDGLNKPLPMKYYDQNNLVMHCSSFSKTLGAGFRVG
WVYAGKYSEHIQHLQLMSTISANTLVQNALVEFLSSHHYEKHLRSLRLKLKKNKKRFYHYLKQNLPTQCRIHYELGGYFL
CIMLPEQASSEEIYKTLLNQNIAVAPSILFNYSQQHQQFIRINCSFDWSNHIQSALDVLTITLKQLSNAKLET
>Mature_472_residues
PMYKSDQLAHQLKSLIEKNIWKAHTKLPSLREQVESSGFSLMTVMNAYQKLEAQGLIYSKEKSGYFVAEQTKPALDSAST
LAPKIEINSSVFKYLKSIQTPNLVSLGSAFPDSELLLPIKLRQIVSQLARYPKSYDQTTNLPPGNLALRKIIAQRYCMQG
IPTQADDIVITSGGLDALNLSLQALTQPGDYIVLQQTTFYGAWQAAERLGLKVITVPEHAHCGIDVDAFEQLILHYPVKV
CWMMFNAHNPLGFTVSEEIKFKIAKLLHQHHIHLIEDDVYEELFDGLNKPLPMKYYDQNNLVMHCSSFSKTLGAGFRVGW
VYAGKYSEHIQHLQLMSTISANTLVQNALVEFLSSHHYEKHLRSLRLKLKKNKKRFYHYLKQNLPTQCRIHYELGGYFLC
IMLPEQASSEEIYKTLLNQNIAVAPSILFNYSQQHQQFIRINCSFDWSNHIQSALDVLTITLKQLSNAKLET

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787710, Length=462, Percent_Identity=44.1558441558442, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1790797, Length=461, Percent_Identity=31.6702819956616, Blast_Score=242, Evalue=5e-65,
Organism=Drosophila melanogaster, GI21356535, Length=375, Percent_Identity=21.3333333333333, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53937; Mature: 53806

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMYKSDQLAHQLKSLIEKNIWKAHTKLPSLREQVESSGFSLMTVMNAYQKLEAQGLIYS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEE
KEKSGYFVAEQTKPALDSASTLAPKIEINSSVFKYLKSIQTPNLVSLGSAFPDSELLLPI
ECCCCEEEECCCCCCCCCHHHCCCEEEECHHHHHHHHHCCCCCEEECCCCCCCCCCEEHH
KLRQIVSQLARYPKSYDQTTNLPPGNLALRKIIAQRYCMQGIPTQADDIVITSGGLDALN
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHH
LSLQALTQPGDYIVLQQTTFYGAWQAAERLGLKVITVPEHAHCGIDVDAFEQLILHYPVK
HHHHHCCCCCCEEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCHH
VCWMMFNAHNPLGFTVSEEIKFKIAKLLHQHHIHLIEDDVYEELFDGLNKPLPMKYYDQN
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCC
NLVMHCSSFSKTLGAGFRVGWVYAGKYSEHIQHLQLMSTISANTLVQNALVEFLSSHHYE
CEEEEECHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KHLRSLRLKLKKNKKRFYHYLKQNLPTQCRIHYELGGYFLCIMLPEQASSEEIYKTLLNQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEECCCCCHHHHHHHHHCC
NIAVAPSILFNYSQQHQQFIRINCSFDWSNHIQSALDVLTITLKQLSNAKLET
CCEECHHHHHCCCHHCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
PMYKSDQLAHQLKSLIEKNIWKAHTKLPSLREQVESSGFSLMTVMNAYQKLEAQGLIYS
CCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEE
KEKSGYFVAEQTKPALDSASTLAPKIEINSSVFKYLKSIQTPNLVSLGSAFPDSELLLPI
ECCCCEEEECCCCCCCCCHHHCCCEEEECHHHHHHHHHCCCCCEEECCCCCCCCCCEEHH
KLRQIVSQLARYPKSYDQTTNLPPGNLALRKIIAQRYCMQGIPTQADDIVITSGGLDALN
HHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHH
LSLQALTQPGDYIVLQQTTFYGAWQAAERLGLKVITVPEHAHCGIDVDAFEQLILHYPVK
HHHHHCCCCCCEEEEEECCHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHCCHH
VCWMMFNAHNPLGFTVSEEIKFKIAKLLHQHHIHLIEDDVYEELFDGLNKPLPMKYYDQN
HHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCC
NLVMHCSSFSKTLGAGFRVGWVYAGKYSEHIQHLQLMSTISANTLVQNALVEFLSSHHYE
CEEEEECHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
KHLRSLRLKLKKNKKRFYHYLKQNLPTQCRIHYELGGYFLCIMLPEQASSEEIYKTLLNQ
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEEEEECCCCCHHHHHHHHHCC
NIAVAPSILFNYSQQHQQFIRINCSFDWSNHIQSALDVLTITLKQLSNAKLET
CCEECHHHHHCCCHHCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]