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The map label for this gene is ydfD [H]

Identifier: 50085038

GI number: 50085038

Start: 1887046

End: 1888446

Strand: Direct

Name: ydfD [H]

Synonym: ACIAD1897

Alternate gene names: 50085038

Gene position: 1887046-1888446 (Clockwise)

Preceding gene: 50085036

Following gene: 50085052

Centisome position: 52.44

GC content: 37.69

Gene sequence:

>1401_bases
ATGACCAAAATTGAACAAGTTATTCATTATGTCGACCAACAACTTAAAAGTCGTCGCTTAACGCCTGGCATGCGATTGCC
CTCTGTCAGAAGTTTAGCGAAACAGCTTAATTTTTCGGTATCAACGGTCGTAAATGCGTATGAACGCATGTTATCTATGG
GACTCATTGAGTCTCGTGCTGGTTCAGGATTTTTTGTATGCGCACCTCTTGAACCTCTTATACTTTCACATATCGAACCA
ATTCAAGATCAAAATCTAGATCCTCTAAAAATTTCCCGTCAGCTTTTAGAGGCCTCCTCTTTTTTAATCAAGGCTGGGTG
TGGCTGGTTACCTGATGACTGGATGCCGCATGAAGCCTTGCGTAAAGCAATTCGTGATACGTCAAAAGATTCAGTTTTTG
AATTAATGAATTATTCATCTCCATTGGGGCTAAGTTCGCTACGTGAATTATTAGCACGACGCTTACATACCAAAGACATT
AACGTGACTCCTGAGCAGATTTTACTGACTGACTCAGGCTCTTACTCAATTGATCTGATTTGTCGTTTCTTACTTAAACC
TGGCGATACAGTATTGCTTGATGATCCCTGCTATTTTAACTTTCGAGCCTTACTCAAAGTACATCAGGTTAAAGTGATTA
GTGTCCGTTATACTCCTGACGGACCAGATATTGAGGCTTTTAAACAGGCGATCATTGAACATCATCCTCGCTTATATATC
ACAAATTCTGGTATTCATAACCCAACGGGCGCAACACTTTCCCAATCCAAAGCACATCAGCTTGTATCGTTGATTGAACA
TGCCAATATGGTGGTTGTAGAAGACGATATTTTCTCGGATTTTGAAACCTCTGCTTCTCCCCGCCTCAGTGCATTGGATG
GACTTAAAAATAGTATTTACATTGGTAGTTTCTCAAAGACTTTATCTGCATCACTACGTTGTGGCTACATCGTGACAAAA
TCAGAATGGATTGATTATTTAATTGATTTAAAAGTCGCAACTAGTTTTAGTCATAATAATTTTTCGGCGCATGTACTTTA
TAAAATATTAACTCATGGTGGATACCGTAAACATATTGAGCAACTTAAAATTCGATTGGCCGATGCCATGATCATTTCAA
TTCACAGATTAGAAAAAATACGAATTCAGCCGTGGATAAGGCCTAAAGCAGGTATTTTTCTATGGTGCGAATTGCCCACA
GATATTAATATCCAAAAATTAATGTCATATTGCACTGAAAAGGGAGTAATTTTAGCTTTGGGTAATTCATTTGGTGAAGC
ACATACATTTCAAAATTTTTTAAGATTTAATATTGCACAATGTATGCATCCAGATTTTTTTAATATCTTAGAAGATGCCA
TGCAATATGCAAGTATGAATCGTCCTCTCAATTCTCTTTAG

Upstream 100 bases:

>100_bases
TTTTTATAGGCTTATATTGTGCTTTACGACAGAGACAATGCAGTACAATTTTAAAAAACTGTACTGCTCATAATTTCCAT
ACAGTTATAGATCGATTTAC

Downstream 100 bases:

>100_bases
CTTTCTGCTGCAGAATGTGGGGCGTAAAATTTGTATATGCGGGATTTATATGGTGTTTTCACCAAAATCTCATTTTCAAC
TAAGCGTTTTAACCGGTCTG

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTKIEQVIHYVDQQLKSRRLTPGMRLPSVRSLAKQLNFSVSTVVNAYERMLSMGLIESRAGSGFFVCAPLEPLILSHIEP
IQDQNLDPLKISRQLLEASSFLIKAGCGWLPDDWMPHEALRKAIRDTSKDSVFELMNYSSPLGLSSLRELLARRLHTKDI
NVTPEQILLTDSGSYSIDLICRFLLKPGDTVLLDDPCYFNFRALLKVHQVKVISVRYTPDGPDIEAFKQAIIEHHPRLYI
TNSGIHNPTGATLSQSKAHQLVSLIEHANMVVVEDDIFSDFETSASPRLSALDGLKNSIYIGSFSKTLSASLRCGYIVTK
SEWIDYLIDLKVATSFSHNNFSAHVLYKILTHGGYRKHIEQLKIRLADAMIISIHRLEKIRIQPWIRPKAGIFLWCELPT
DINIQKLMSYCTEKGVILALGNSFGEAHTFQNFLRFNIAQCMHPDFFNILEDAMQYASMNRPLNSL

Sequences:

>Translated_466_residues
MTKIEQVIHYVDQQLKSRRLTPGMRLPSVRSLAKQLNFSVSTVVNAYERMLSMGLIESRAGSGFFVCAPLEPLILSHIEP
IQDQNLDPLKISRQLLEASSFLIKAGCGWLPDDWMPHEALRKAIRDTSKDSVFELMNYSSPLGLSSLRELLARRLHTKDI
NVTPEQILLTDSGSYSIDLICRFLLKPGDTVLLDDPCYFNFRALLKVHQVKVISVRYTPDGPDIEAFKQAIIEHHPRLYI
TNSGIHNPTGATLSQSKAHQLVSLIEHANMVVVEDDIFSDFETSASPRLSALDGLKNSIYIGSFSKTLSASLRCGYIVTK
SEWIDYLIDLKVATSFSHNNFSAHVLYKILTHGGYRKHIEQLKIRLADAMIISIHRLEKIRIQPWIRPKAGIFLWCELPT
DINIQKLMSYCTEKGVILALGNSFGEAHTFQNFLRFNIAQCMHPDFFNILEDAMQYASMNRPLNSL
>Mature_465_residues
TKIEQVIHYVDQQLKSRRLTPGMRLPSVRSLAKQLNFSVSTVVNAYERMLSMGLIESRAGSGFFVCAPLEPLILSHIEPI
QDQNLDPLKISRQLLEASSFLIKAGCGWLPDDWMPHEALRKAIRDTSKDSVFELMNYSSPLGLSSLRELLARRLHTKDIN
VTPEQILLTDSGSYSIDLICRFLLKPGDTVLLDDPCYFNFRALLKVHQVKVISVRYTPDGPDIEAFKQAIIEHHPRLYIT
NSGIHNPTGATLSQSKAHQLVSLIEHANMVVVEDDIFSDFETSASPRLSALDGLKNSIYIGSFSKTLSASLRCGYIVTKS
EWIDYLIDLKVATSFSHNNFSAHVLYKILTHGGYRKHIEQLKIRLADAMIISIHRLEKIRIQPWIRPKAGIFLWCELPTD
INIQKLMSYCTEKGVILALGNSFGEAHTFQNFLRFNIAQCMHPDFFNILEDAMQYASMNRPLNSL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=334, Percent_Identity=22.1556886227545, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI33469970, Length=334, Percent_Identity=22.1556886227545, Blast_Score=75, Evalue=9e-14,
Organism=Escherichia coli, GI1787710, Length=459, Percent_Identity=26.1437908496732, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1790797, Length=455, Percent_Identity=26.5934065934066, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21356535, Length=301, Percent_Identity=21.5946843853821, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 52791; Mature: 52660

Theoretical pI: Translated: 8.05; Mature: 8.05

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKIEQVIHYVDQQLKSRRLTPGMRLPSVRSLAKQLNFSVSTVVNAYERMLSMGLIESRA
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GSGFFVCAPLEPLILSHIEPIQDQNLDPLKISRQLLEASSFLIKAGCGWLPDDWMPHEAL
CCCEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
RKAIRDTSKDSVFELMNYSSPLGLSSLRELLARRLHTKDINVTPEQILLTDSGSYSIDLI
HHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHH
CRFLLKPGDTVLLDDPCYFNFRALLKVHQVKVISVRYTPDGPDIEAFKQAIIEHHPRLYI
HHHHHCCCCEEEECCCCCHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEE
TNSGIHNPTGATLSQSKAHQLVSLIEHANMVVVEDDIFSDFETSASPRLSALDGLKNSIY
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCCCCHHHHHCCCCCEE
IGSFSKTLSASLRCGYIVTKSEWIDYLIDLKVATSFSHNNFSAHVLYKILTHGGYRKHIE
EECCHHHHHHCCCCCEEEEHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHH
QLKIRLADAMIISIHRLEKIRIQPWIRPKAGIFLWCELPTDINIQKLMSYCTEKGVILAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEE
GNSFGEAHTFQNFLRFNIAQCMHPDFFNILEDAMQYASMNRPLNSL
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TKIEQVIHYVDQQLKSRRLTPGMRLPSVRSLAKQLNFSVSTVVNAYERMLSMGLIESRA
CHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
GSGFFVCAPLEPLILSHIEPIQDQNLDPLKISRQLLEASSFLIKAGCGWLPDDWMPHEAL
CCCEEEECCCCHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
RKAIRDTSKDSVFELMNYSSPLGLSSLRELLARRLHTKDINVTPEQILLTDSGSYSIDLI
HHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHH
CRFLLKPGDTVLLDDPCYFNFRALLKVHQVKVISVRYTPDGPDIEAFKQAIIEHHPRLYI
HHHHHCCCCEEEECCCCCHHHHHHHHHHEEEEEEEEECCCCCCHHHHHHHHHHCCCEEEE
TNSGIHNPTGATLSQSKAHQLVSLIEHANMVVVEDDIFSDFETSASPRLSALDGLKNSIY
ECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHCCCCCCCCCHHHHHCCCCCEE
IGSFSKTLSASLRCGYIVTKSEWIDYLIDLKVATSFSHNNFSAHVLYKILTHGGYRKHIE
EECCHHHHHHCCCCCEEEEHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHCCCHHHHHH
QLKIRLADAMIISIHRLEKIRIQPWIRPKAGIFLWCELPTDINIQKLMSYCTEKGVILAL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCEEEEE
GNSFGEAHTFQNFLRFNIAQCMHPDFFNILEDAMQYASMNRPLNSL
CCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]