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The map label for this gene is 50084933

Identifier: 50084933

GI number: 50084933

Start: 1791699

End: 1793105

Strand: Direct

Name: 50084933

Synonym: ACIAD1783

Alternate gene names: NA

Gene position: 1791699-1793105 (Clockwise)

Preceding gene: 50084932

Following gene: 50084935

Centisome position: 49.79

GC content: 38.17

Gene sequence:

>1407_bases
ATGATGTCTTCATTGTCTGAATGCCTAGACCAAAAACAGTTTTGTATTTTGGTTGAATATTTATGTTCTGTAAAAAGCCC
CTTAGCTGTAAGAAAAACCTTGGCTAATTTTCCAGCCATGATGACTTTGGCTGATCGCGTACATGCAGATAATGATCCAG
CCCCTTTAGACTTAGCGACAAAATATCCTGATACGGTTGATAAGCTTATACATTTTTCGGGCAAAGCACGAGATATCAAA
GACCTTGAGAGATTTTTAAATGACCTGGAAAATACAACAATACGTAACCTGCTTTTGGTGACAGGTGATAAGCTCAAAAG
TCATGATTTTGGATATGAAGTTGCAGCACAGCGTACTCGTTATTTAGAATCTGTAAGTGCCATCATGGCCGCGAAACAAC
GTCAGATTTTTAAAATAGGTGTAGCATTTAATCCATTTAAATACACAGAAGCAGAATCAGATGCTCAGTACCTAAAGCTG
CACAAAAAAATAAAAGCAGGTGCAGATTTTCTCATTACACAACTTGGGTTTGATGTAGAGTGTTTACAACAGACTCAAGT
ATTTCTACAAAAAAACTATCCGAACTTTTCAGCGCTTGCATGTGTTATGCCACTCACATTAAAACGCGCACAGTTTATGG
TGAAAAATCGGGTCGCTGGAATTGTGATATCGGATCATGTCTTGCAAACATTGGAGAAGGAATACCAGTCTGATCCAATT
CAGGCAGAGATCAATGTTTATGCCCGCTGCGCATTACAAATATTAATTTGTAAACATTTTGGCTATGCAGGTGTTCATTT
GTCTGCTTGCCATAAAGAAGATGAACAAAAAAAACTTGAGCAAGCATTAAAAGTATTTGAAAATTTTTCTTTAAACGAAT
GCCAGCAAGCATGGAAAGATTTATGGCAAGCTGATGCCCAAGGCGACTTTAAACCCAATGTGAAAATATCTTCAAAGCCA
GTTACTCAAACTCAAATTTTGAAATACAAAAAGATGCATACGATGCATCGTATGTTTTTTGAGTCAAAAATGGCGCGAAC
TATTGGTCATTTCGTGTTCAAACCATCATTTTGGAATAGATCGAATGCTCAAAATATTTTGCTTAAAATTGAGCACTCAA
GCAAACATCGTTTAGTGGGCTGTGAGAGTTGTGGGGAATGTCGATTGGGCGATACGCTCTACATCTGCCCAGAAACTTGT
CCTAAAGGTTTGGCAAATGGCCCATGTGGCGGAACCTCTTTAGACCGTTGTGAGTTTGAAGACCGTGAATGTATCCATTC
AGTGAAAGCACGCTTAGCGAAAAAAATTCATCAAACAGAAATTCTAAAAACTAAACTGATACCCGCTATTTCTATAACTA
CACGTCACACCAGCTCATGGAAAAGCTGGTTTACAGACACAAAATGA

Upstream 100 bases:

>100_bases
AGGATCATACCCATACTCAAGTATGGCGGGTTTTACTTTGAGGAAGGATAACTTATAATAAACACTTAAATTTTTTCATG
TTTAAGTTTATTTCTCCTTA

Downstream 100 bases:

>100_bases
CGCAAATAAAGTTAGTTTTAAATTTTAATCCTTTTAATATTGGTCTGAGCTACTAACGATAGCAATGCTAGTAAAGCGAT
AACATAACCCTCATGAAGTG

Product: methylenetetrahydrofolate reductase

Products: NA

Alternate protein names: 5 10-Methylene-Tetrahydrofolate Reductase MetF; Methylenetetrahydrofolate Reductase Family

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLATKYPDTVDKLIHFSGKARDIK
DLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTRYLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKL
HKKIKAGADFLITQLGFDVECLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKDLWQADAQGDFKPNVKISSKP
VTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNRSNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETC
PKGLANGPCGGTSLDRCEFEDRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK

Sequences:

>Translated_468_residues
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLATKYPDTVDKLIHFSGKARDIK
DLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTRYLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKL
HKKIKAGADFLITQLGFDVECLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKDLWQADAQGDFKPNVKISSKP
VTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNRSNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETC
PKGLANGPCGGTSLDRCEFEDRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK
>Mature_468_residues
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLATKYPDTVDKLIHFSGKARDIK
DLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTRYLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKL
HKKIKAGADFLITQLGFDVECLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKDLWQADAQGDFKPNVKISSKP
VTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNRSNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETC
PKGLANGPCGGTSLDRCEFEDRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK

Specific function: Unknown

COG id: COG0685

COG function: function code E; 5,10-methylenetetrahydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 53318; Mature: 53318

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLAT
CCCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
KYPDTVDKLIHFSGKARDIKDLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTR
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHEEEEECCCCCCCCCCHHHHHHHHH
YLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKLHKKIKAGADFLITQLGFDVE
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHH
CLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHCCCCC
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKD
EEHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LWQADAQGDFKPNVKISSKPVTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNR
HHHCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETCPKGLANGPCGGTSLDRCEFE
CCCCEEEEEEECCCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCH
DRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCC
>Mature Secondary Structure
MMSSLSECLDQKQFCILVEYLCSVKSPLAVRKTLANFPAMMTLADRVHADNDPAPLDLAT
CCCCHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCC
KYPDTVDKLIHFSGKARDIKDLERFLNDLENTTIRNLLLVTGDKLKSHDFGYEVAAQRTR
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHEEEEECCCCCCCCCCHHHHHHHHH
YLESVSAIMAAKQRQIFKIGVAFNPFKYTEAESDAQYLKLHKKIKAGADFLITQLGFDVE
HHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHCCCHH
CLQQTQVFLQKNYPNFSALACVMPLTLKRAQFMVKNRVAGIVISDHVLQTLEKEYQSDPI
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHCCCCC
QAEINVYARCALQILICKHFGYAGVHLSACHKEDEQKKLEQALKVFENFSLNECQQAWKD
EEHHHHHHHHHHHHHHHHHCCCCCEEHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHH
LWQADAQGDFKPNVKISSKPVTQTQILKYKKMHTMHRMFFESKMARTIGHFVFKPSFWNR
HHHCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SNAQNILLKIEHSSKHRLVGCESCGECRLGDTLYICPETCPKGLANGPCGGTSLDRCEFE
CCCCEEEEEEECCCCCCEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCH
DRECIHSVKARLAKKIHQTEILKTKLIPAISITTRHTSSWKSWFTDTK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA