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The map label for this gene is mdcH [H]

Identifier: 50084910

GI number: 50084910

Start: 1764747

End: 1765673

Strand: Direct

Name: mdcH [H]

Synonym: ACIAD1759

Alternate gene names: 50084910

Gene position: 1764747-1765673 (Clockwise)

Preceding gene: 50084909

Following gene: 50084911

Centisome position: 49.04

GC content: 40.99

Gene sequence:

>927_bases
ATGAGTTCGATTTGGGTATATCCAGGACAGGGTGCTCAGAAGATTAATATGCTACATGATCTTCCAAAGCATCCATTGGT
TGATCGCTATCTTGAACAAGCATCTGATGTATTAAATGAAAATATTATGCTGCTTGATCAGGCCGATTCACTCAAATCAA
CTTACTCGGTGCAATTATGTTTATATGTGGCAGGTGTCATTAGCTCTGAATTGTTGCGATTGCATGGTGTAAAACCCAAA
TTTGTGGCTGGTTTATCGATTGGGGCGTGGGCTGCTGCGACAGTTGCACATGTGATTCGTTTTGAAGATGGTTTGAAATT
GGTCGCCAAAAGAGCACAACTGATGCAGCAGGCTTACCCTAAAGGTTACGGAATGACCGCCATTCTGGGAGCAGATTGCT
CTCAAATTGAGCAATGGATTGAGCAAACTCAACAAAATCAGCAAGTATTCATTGCAAATCTGAATACTGAAAATCAAGTG
GTCATTTCTGGTTCAGAGCAAGCCATGCAGTATGTAATTCATCATGCACAGCAAAATGGAGCAATTGCAAAAAAGGTTGA
AATCAGTGTGCCCTCACATTGCGTACTATTGGAAAAACAGGCACACCAACTGGCGGGTTTTATGGAGGAAATACCTACGC
AACAACCTACGATTCAATATTTAAGTGGTACATCGGCACGTTTACTCAGAACGAATACACAGATTATGAATGATCTCGCA
TTCAATATGAGTCGTATGATTGACTGGCACAATACAGTTCAGGCTGCTTGGGAACGCGGTGCTCGTTTACAAATAGAAGC
CTTGCCTGGCACGGTACTTACTAGTTTGGCTCGAAAAATATTTAAAGAAGGAACGTTATTGTCGTTCCAAAACACATCAA
TTGAAACTCTGATCATTGCCATGCAAAAACAACAAGATTTTGTATAA

Upstream 100 bases:

>100_bases
GGCACTTCAGGAATGGGCGAGCGTTACAGGGAAGGTGTTACTTAAGCGTAATGAGGGTGCGTTTCTGGTGGAAAATCCGT
GGCGTTAAAGGAGTAACAAT

Downstream 100 bases:

>100_bases
AGCATAATCAGAAAATAATGAAACTCAAAGGATAGAGGAAATTTGACATGATTATCTATGGAGTAGGTTTACTGGCACTT
TGCACTTTAGTGGGTGTAAT

Product: acyl-carrier-protein S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MSSIWVYPGQGAQKINMLHDLPKHPLVDRYLEQASDVLNENIMLLDQADSLKSTYSVQLCLYVAGVISSELLRLHGVKPK
FVAGLSIGAWAAATVAHVIRFEDGLKLVAKRAQLMQQAYPKGYGMTAILGADCSQIEQWIEQTQQNQQVFIANLNTENQV
VISGSEQAMQYVIHHAQQNGAIAKKVEISVPSHCVLLEKQAHQLAGFMEEIPTQQPTIQYLSGTSARLLRTNTQIMNDLA
FNMSRMIDWHNTVQAAWERGARLQIEALPGTVLTSLARKIFKEGTLLSFQNTSIETLIIAMQKQQDFV

Sequences:

>Translated_308_residues
MSSIWVYPGQGAQKINMLHDLPKHPLVDRYLEQASDVLNENIMLLDQADSLKSTYSVQLCLYVAGVISSELLRLHGVKPK
FVAGLSIGAWAAATVAHVIRFEDGLKLVAKRAQLMQQAYPKGYGMTAILGADCSQIEQWIEQTQQNQQVFIANLNTENQV
VISGSEQAMQYVIHHAQQNGAIAKKVEISVPSHCVLLEKQAHQLAGFMEEIPTQQPTIQYLSGTSARLLRTNTQIMNDLA
FNMSRMIDWHNTVQAAWERGARLQIEALPGTVLTSLARKIFKEGTLLSFQNTSIETLIIAMQKQQDFV
>Mature_307_residues
SSIWVYPGQGAQKINMLHDLPKHPLVDRYLEQASDVLNENIMLLDQADSLKSTYSVQLCLYVAGVISSELLRLHGVKPKF
VAGLSIGAWAAATVAHVIRFEDGLKLVAKRAQLMQQAYPKGYGMTAILGADCSQIEQWIEQTQQNQQVFIANLNTENQVV
ISGSEQAMQYVIHHAQQNGAIAKKVEISVPSHCVLLEKQAHQLAGFMEEIPTQQPTIQYLSGTSARLLRTNTQIMNDLAF
NMSRMIDWHNTVQAAWERGARLQIEALPGTVLTSLARKIFKEGTLLSFQNTSIETLIIAMQKQQDFV

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=303, Percent_Identity=25.7425742574257, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI1787334, Length=283, Percent_Identity=31.8021201413428, Blast_Score=135, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71984332, Length=299, Percent_Identity=22.0735785953177, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24665753, Length=311, Percent_Identity=25.4019292604502, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34330; Mature: 34199

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIWVYPGQGAQKINMLHDLPKHPLVDRYLEQASDVLNENIMLLDQADSLKSTYSVQLC
CCCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
LYVAGVISSELLRLHGVKPKFVAGLSIGAWAAATVAHVIRFEDGLKLVAKRAQLMQQAYP
HHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KGYGMTAILGADCSQIEQWIEQTQQNQQVFIANLNTENQVVISGSEQAMQYVIHHAQQNG
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
AIAKKVEISVPSHCVLLEKQAHQLAGFMEEIPTQQPTIQYLSGTSARLLRTNTQIMNDLA
CEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
FNMSRMIDWHNTVQAAWERGARLQIEALPGTVLTSLARKIFKEGTLLSFQNTSIETLIIA
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCEEHEEE
MQKQQDFV
EHHHCCCC
>Mature Secondary Structure 
SSIWVYPGQGAQKINMLHDLPKHPLVDRYLEQASDVLNENIMLLDQADSLKSTYSVQLC
CCEEEECCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHH
LYVAGVISSELLRLHGVKPKFVAGLSIGAWAAATVAHVIRFEDGLKLVAKRAQLMQQAYP
HHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KGYGMTAILGADCSQIEQWIEQTQQNQQVFIANLNTENQVVISGSEQAMQYVIHHAQQNG
CCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHHHCCC
AIAKKVEISVPSHCVLLEKQAHQLAGFMEEIPTQQPTIQYLSGTSARLLRTNTQIMNDLA
CEEEEEEECCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHH
FNMSRMIDWHNTVQAAWERGARLQIEALPGTVLTSLARKIFKEGTLLSFQNTSIETLIIA
HHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEEECCCCCEEHEEE
MQKQQDFV
EHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]