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The map label for this gene is pobR

Identifier: 50084872

GI number: 50084872

Start: 1725001

End: 1725816

Strand: Reverse

Name: pobR

Synonym: ACIAD1718

Alternate gene names: 50084872

Gene position: 1725816-1725001 (Counterclockwise)

Preceding gene: 50084874

Following gene: 50084871

Centisome position: 47.96

GC content: 42.52

Gene sequence:

>816_bases
ATGGAACAACATCACCAATACCTTGCACATCCCCATTCAAGTGAAGAAATACGTACGGAAGATTACATTGCAGGCTTGGC
CAAAGGCTTAGCGCTTTTAGAAGCATTTGGAATTGACAGACAACGACTGAACGTGACACAGGTTGCAGAGCGTACTGGTA
TAAGCAGAACAGCTGCACGGCGTTATTTAAAGACACTTAAATTTTTGGGTTATTTAGATACCGATGAGCACTATTTTTGG
CTTACACATCGTGTTTTACGTTTTTCTAGTTCTTATTTAAGCTCGGCACATTTACCCAAAGTGGCACAGTCATTTTTAAA
TCTACTGTGTGCTCAAACCAGCCTCACCTTTTCAATTGTGGTGCTCGATGAGCATGAAGTTGTACCTGTTGCGCGTAGTT
ATTTACCCCAGCAAGATAATCTTCGCGTGAGCCCCTATGGGATGCATTTGGGTAATCGTTTGCCTGCCCACGCCACCTCT
ACCGGTAAAGTATTACTTTCTGTTCTGGATCGTGAAGTACAAATTGAATGGATTGAAAAATATGGTCTGAAGCGCCTCAC
GCCTTATACCATTACCGATGAACATACTTTTTTAGAAACATTAGATGCTGTTCGGCAATCGGACTACTGTTTGTCTACTG
AGGAACATGAACTGGGTCTGATTGCGATTGCGGTACCCGTTTTAAACGCACAGGGGCTTACCATTGCAGCACTTAATTGT
ATGTCACAAACCAATCGGGTGCAGCCACAGTATCTTATCGATCAAGTTTTACCTTTATTACGCAATACTGCGAATGAGCT
GCGTAATTTGGTATAA

Upstream 100 bases:

>100_bases
CCGCCTCATTAAAAAGACATCTATAATCAAGGCTCAAAATTATCCGATTAGCATTACAACTGTCCGATGATCGGACAAAA
CCATTTTGGATTTGAATGTT

Downstream 100 bases:

>100_bases
TTTTAATCATAGATATTTGTTATCTTATTAAAAAACTTTAAAAGAGTTGAGATTCAATATTAGATTTTTAATAAGAAAGA
AAATATTTAGATATATAATC

Product: p-hydroxybenzoate hydroxylase transcriptional activator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MEQHHQYLAHPHSSEEIRTEDYIAGLAKGLALLEAFGIDRQRLNVTQVAERTGISRTAARRYLKTLKFLGYLDTDEHYFW
LTHRVLRFSSSYLSSAHLPKVAQSFLNLLCAQTSLTFSIVVLDEHEVVPVARSYLPQQDNLRVSPYGMHLGNRLPAHATS
TGKVLLSVLDREVQIEWIEKYGLKRLTPYTITDEHTFLETLDAVRQSDYCLSTEEHELGLIAIAVPVLNAQGLTIAALNC
MSQTNRVQPQYLIDQVLPLLRNTANELRNLV

Sequences:

>Translated_271_residues
MEQHHQYLAHPHSSEEIRTEDYIAGLAKGLALLEAFGIDRQRLNVTQVAERTGISRTAARRYLKTLKFLGYLDTDEHYFW
LTHRVLRFSSSYLSSAHLPKVAQSFLNLLCAQTSLTFSIVVLDEHEVVPVARSYLPQQDNLRVSPYGMHLGNRLPAHATS
TGKVLLSVLDREVQIEWIEKYGLKRLTPYTITDEHTFLETLDAVRQSDYCLSTEEHELGLIAIAVPVLNAQGLTIAALNC
MSQTNRVQPQYLIDQVLPLLRNTANELRNLV
>Mature_271_residues
MEQHHQYLAHPHSSEEIRTEDYIAGLAKGLALLEAFGIDRQRLNVTQVAERTGISRTAARRYLKTLKFLGYLDTDEHYFW
LTHRVLRFSSSYLSSAHLPKVAQSFLNLLCAQTSLTFSIVVLDEHEVVPVARSYLPQQDNLRVSPYGMHLGNRLPAHATS
TGKVLLSVLDREVQIEWIEKYGLKRLTPYTITDEHTFLETLDAVRQSDYCLSTEEHELGLIAIAVPVLNAQGLTIAALNC
MSQTNRVQPQYLIDQVLPLLRNTANELRNLV

Specific function: Positive regulator of the pobA gene for p- hydroxybenzoate hydroxylase

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain

Homologues:

Organism=Escherichia coli, GI1788131, Length=241, Percent_Identity=30.7053941908714, Blast_Score=101, Evalue=6e-23,
Organism=Escherichia coli, GI1786468, Length=227, Percent_Identity=28.1938325991189, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786715, Length=261, Percent_Identity=25.2873563218391, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082359, Length=229, Percent_Identity=24.8908296943231, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1789999, Length=248, Percent_Identity=25, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): POBR_ACIAD (Q43992)

Other databases:

- EMBL:   L05770
- EMBL:   CR543861
- PIR:   A36893
- RefSeq:   YP_046382.1
- ProteinModelPortal:   Q43992
- STRING:   Q43992
- GeneID:   2879804
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1718
- NMPDR:   fig|62977.3.peg.1644
- eggNOG:   COG1414
- HOGENOM:   HBG739407
- OMA:   YLETDGS
- ProtClustDB:   CLSK927692
- BioCyc:   ASP62977:ACIAD1718-MONOMER
- GO:   GO:0006350
- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00346
- TIGRFAMs:   TIGR02431

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR

EC number: NA

Molecular weight: Translated: 30765; Mature: 30765

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS51077 HTH_ICLR; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQHHQYLAHPHSSEEIRTEDYIAGLAKGLALLEAFGIDRQRLNVTQVAERTGISRTAAR
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
RYLKTLKFLGYLDTDEHYFWLTHRVLRFSSSYLSSAHLPKVAQSFLNLLCAQTSLTFSIV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEE
VLDEHEVVPVARSYLPQQDNLRVSPYGMHLGNRLPAHATSTGKVLLSVLDREVQIEWIEK
EECCCCCHHHHHHHCCCCCCEEECCCCHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
YGLKRLTPYTITDEHTFLETLDAVRQSDYCLSTEEHELGLIAIAVPVLNAQGLTIAALNC
CCCHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHH
MSQTNRVQPQYLIDQVLPLLRNTANELRNLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEQHHQYLAHPHSSEEIRTEDYIAGLAKGLALLEAFGIDRQRLNVTQVAERTGISRTAAR
CCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHH
RYLKTLKFLGYLDTDEHYFWLTHRVLRFSSSYLSSAHLPKVAQSFLNLLCAQTSLTFSIV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEE
VLDEHEVVPVARSYLPQQDNLRVSPYGMHLGNRLPAHATSTGKVLLSVLDREVQIEWIEK
EECCCCCHHHHHHHCCCCCCEEECCCCHHHCCCCCCCCCHHHHHHHHHHCCHHHHHHHHH
YGLKRLTPYTITDEHTFLETLDAVRQSDYCLSTEEHELGLIAIAVPVLNAQGLTIAALNC
CCCHHCCCEEECCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHH
MSQTNRVQPQYLIDQVLPLLRNTANELRNLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8331077