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The map label for this gene is aroD [H]

Identifier: 50084867

GI number: 50084867

Start: 1717288

End: 1718112

Strand: Direct

Name: aroD [H]

Synonym: ACIAD1713

Alternate gene names: 50084867

Gene position: 1717288-1718112 (Clockwise)

Preceding gene: 50084866

Following gene: 50084868

Centisome position: 47.72

GC content: 37.33

Gene sequence:

>825_bases
TTGTTGATGTCATTGCCTATATTGTCAACGACCTATGCGGCTGAAAATACTGTACCAGCATCTAAATCAACTTATGTTGT
AAAAAATTTAAACATTGGTGATTTACCTGTTAAAACCCTCGTGCCAATCACTGCTAAAACAAGAGAGCAAGCTTTGGCAC
AGGCAAAAGTAATCGCGGAAAATAAAGATGCAGATATTGCCGAATTTCGTATCGATTTACTTGAGTTTGCCAGCGATACC
AAAAAAGTCATTGCTTTAGGACAAGAACTTAATCAGATTTTAAAAGATAAACCGTTACTTGCAACAATTCGTACGTCTAA
CGAAGGTGGAAAGTTGAAAGTAACAGATCAAGAATATGAAAAAATCTACAGTGAATATCTTAAAAAACCGTTCATGCAAT
TGCTAGATATTGAAATGTTTCGTGATCAGGCTGCAGTTGCCAAATTGACCAAACTTGCGCACCAGAAAAAAGTATTGGTT
GTCATGTCAAACCATGATTTTGATAAAACACCAAGTGAGCAGGAAATTGTAAGCCGTCTATTGAAGCAAGATCAAATGGG
TGCAGATATTCTAAAAATTGCAGTCATGCCAAAATCTAAACAAGATGTATTTACATTGATGAATGCGACATTAAAAGTCA
GTGAGCAAAGTACAAAGCCACTACTTACCATGTCAATGGGGCGTTTAGGTACGATTTCGCGTATTGCAACTGCAAATATG
GGCGGTAGCTTAAGCTTCGGTATGATTGGGGAGGCTTCTGCACCAGGTCAAATTGATGTTACTGCACTTAAACAATTCCT
TAAAACAGTTCAACCTACACCTTAA

Upstream 100 bases:

>100_bases
GGGCCGTATATCTTTCGGTATACAGCCTCCATAATTTTACAAGGAAACGTAAATGTTCAATACAAACAAACTGGTTAAAC
AACTTTGTCTAAGTGGTGCG

Downstream 100 bases:

>100_bases
ATAAGACAGGGAACATGTCATGAAATTAACTTCTTTACGCGTATCTTTATTGGCGCTGGGCTTGGTAACATCAGGTTTTG
CTGCGGCAGAAACTTATACT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MLMSLPILSTTYAAENTVPASKSTYVVKNLNIGDLPVKTLVPITAKTREQALAQAKVIAENKDADIAEFRIDLLEFASDT
KKVIALGQELNQILKDKPLLATIRTSNEGGKLKVTDQEYEKIYSEYLKKPFMQLLDIEMFRDQAAVAKLTKLAHQKKVLV
VMSNHDFDKTPSEQEIVSRLLKQDQMGADILKIAVMPKSKQDVFTLMNATLKVSEQSTKPLLTMSMGRLGTISRIATANM
GGSLSFGMIGEASAPGQIDVTALKQFLKTVQPTP

Sequences:

>Translated_274_residues
MLMSLPILSTTYAAENTVPASKSTYVVKNLNIGDLPVKTLVPITAKTREQALAQAKVIAENKDADIAEFRIDLLEFASDT
KKVIALGQELNQILKDKPLLATIRTSNEGGKLKVTDQEYEKIYSEYLKKPFMQLLDIEMFRDQAAVAKLTKLAHQKKVLV
VMSNHDFDKTPSEQEIVSRLLKQDQMGADILKIAVMPKSKQDVFTLMNATLKVSEQSTKPLLTMSMGRLGTISRIATANM
GGSLSFGMIGEASAPGQIDVTALKQFLKTVQPTP
>Mature_274_residues
MLMSLPILSTTYAAENTVPASKSTYVVKNLNIGDLPVKTLVPITAKTREQALAQAKVIAENKDADIAEFRIDLLEFASDT
KKVIALGQELNQILKDKPLLATIRTSNEGGKLKVTDQEYEKIYSEYLKKPFMQLLDIEMFRDQAAVAKLTKLAHQKKVLV
VMSNHDFDKTPSEQEIVSRLLKQDQMGADILKIAVMPKSKQDVFTLMNATLKVSEQSTKPLLTMSMGRLGTISRIATANM
GGSLSFGMIGEASAPGQIDVTALKQFLKTVQPTP

Specific function: Catalyzes the catabolic dehydration of dehydroquinate to dehydroshikimate [H]

COG id: COG0710

COG function: function code E; 3-dehydroquinate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I 3-dehydroquinase family [H]

Homologues:

Organism=Escherichia coli, GI1787984, Length=249, Percent_Identity=38.9558232931727, Blast_Score=167, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018508
- InterPro:   IPR013785
- InterPro:   IPR001381 [H]

Pfam domain/function: PF01487 DHquinase_I [H]

EC number: =4.2.1.10 [H]

Molecular weight: Translated: 30144; Mature: 30144

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS01028 DEHYDROQUINASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLMSLPILSTTYAAENTVPASKSTYVVKNLNIGDLPVKTLVPITAKTREQALAQAKVIAE
CEEECCCHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHC
NKDADIAEFRIDLLEFASDTKKVIALGQELNQILKDKPLLATIRTSNEGGKLKVTDQEYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECHHHHH
KIYSEYLKKPFMQLLDIEMFRDQAAVAKLTKLAHQKKVLVVMSNHDFDKTPSEQEIVSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHH
LKQDQMGADILKIAVMPKSKQDVFTLMNATLKVSEQSTKPLLTMSMGRLGTISRIATANM
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHEECCCCCCCEEEECCCCCCHHHHHHHCCC
GGSLSFGMIGEASAPGQIDVTALKQFLKTVQPTP
CCCEEECCCCCCCCCCEEEHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLMSLPILSTTYAAENTVPASKSTYVVKNLNIGDLPVKTLVPITAKTREQALAQAKVIAE
CEEECCCHHHHHCCCCCCCCCCCEEEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHHHC
NKDADIAEFRIDLLEFASDTKKVIALGQELNQILKDKPLLATIRTSNEGGKLKVTDQEYE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEECHHHHH
KIYSEYLKKPFMQLLDIEMFRDQAAVAKLTKLAHQKKVLVVMSNHDFDKTPSEQEIVSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHH
LKQDQMGADILKIAVMPKSKQDVFTLMNATLKVSEQSTKPLLTMSMGRLGTISRIATANM
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHEECCCCCCCEEEECCCCCCHHHHHHHCCC
GGSLSFGMIGEASAPGQIDVTALKQFLKTVQPTP
CCCEEECCCCCCCCCCEEEHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592351 [H]