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The map label for this gene is dcaR [H]

Identifier: 50084843

GI number: 50084843

Start: 1692380

End: 1693225

Strand: Reverse

Name: dcaR [H]

Synonym: ACIAD1688

Alternate gene names: 50084843

Gene position: 1693225-1692380 (Counterclockwise)

Preceding gene: 50084844

Following gene: 50084841

Centisome position: 47.05

GC content: 39.72

Gene sequence:

>846_bases
ATGTCCCCAAGCGCTGAAACAAAAAACAATGATAAAACGCTTAATTTTGATGAAATTCGTTTAGATCCTATTTCCCATAT
TCATCGTGAAAACAATCCTCAATTCATTGCTTCTTTAGCACGCGGTTTAGAGTTATTGCGCTGTTTCTCATTACAACATC
AAGTATTGGGTAATCAGGAACTTGCTAAAATGACAGGTTTACCCAAACCAACAATTGCTCGTATTACCAATACTTTGGTC
AGCTTAGGCTATTTAAAACAAATGCCAAATTCTCCTAAATATATGCTTGATTTGGGAGTTTTATCATTGGGCTATGCAGC
CTTGTCTAATCTGAGTATTCGCACTACAGCGCACCGTTTTATGGAAGAAATGAGTATGTATGCACAGGCACCAGTTGCAT
TGGCTGCACGTGATCGTTTAAATATGCTCTATTTGGATGTAGTGCAAACCAATAGTACGATGCGCCGTCCAATCGGTTCA
ACATTACCCTTGCATAACAGCTCTATGGGACGTGCCTGCCTAGCCGCAACGCCAAAACAGGAACGTTATTTCTTACTCGA
AGCCATTCAAAAACGTGAACCAGAAAACTGGATCGAGATTAAGGAAAAACTCGATATTGCATTCGATCAATATGCCGAAT
ATGGCTATTGCCTATCTTTAGGAGAATGGCAGCAGGGAATCAACTCTGTTGCGGTGCCTTTAATGAGCACAAAACATGGT
CTGTATGTTTTTAACTGTGGAGCACCTTCTTACGCCTTGAGTACCGAAAAATTAATTGAAGATATTGGGCCGCGATTAAA
ATATATGGTAAACAGTATTCAGGATGCTTTGACAGAAAGTCTTTAA

Upstream 100 bases:

>100_bases
ATATCCATTCATCACAACAGCATTGTGATGAATGGATTCAATTTACAAAGCAAAATAAAATACCTTATCATCTGGGCTTA
TTCATTCATTTGAGAAGTCA

Downstream 100 bases:

>100_bases
ATTAAAAAGGAGCAGCCCGCCTGCTCCAAGAGAATCAACCTTGTTGAATCACTTTTCTATCTTTTAAATCATGTAATTCT
TTATCAGATAAAAATCGATT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSPSAETKNNDKTLNFDEIRLDPISHIHRENNPQFIASLARGLELLRCFSLQHQVLGNQELAKMTGLPKPTIARITNTLV
SLGYLKQMPNSPKYMLDLGVLSLGYAALSNLSIRTTAHRFMEEMSMYAQAPVALAARDRLNMLYLDVVQTNSTMRRPIGS
TLPLHNSSMGRACLAATPKQERYFLLEAIQKREPENWIEIKEKLDIAFDQYAEYGYCLSLGEWQQGINSVAVPLMSTKHG
LYVFNCGAPSYALSTEKLIEDIGPRLKYMVNSIQDALTESL

Sequences:

>Translated_281_residues
MSPSAETKNNDKTLNFDEIRLDPISHIHRENNPQFIASLARGLELLRCFSLQHQVLGNQELAKMTGLPKPTIARITNTLV
SLGYLKQMPNSPKYMLDLGVLSLGYAALSNLSIRTTAHRFMEEMSMYAQAPVALAARDRLNMLYLDVVQTNSTMRRPIGS
TLPLHNSSMGRACLAATPKQERYFLLEAIQKREPENWIEIKEKLDIAFDQYAEYGYCLSLGEWQQGINSVAVPLMSTKHG
LYVFNCGAPSYALSTEKLIEDIGPRLKYMVNSIQDALTESL
>Mature_280_residues
SPSAETKNNDKTLNFDEIRLDPISHIHRENNPQFIASLARGLELLRCFSLQHQVLGNQELAKMTGLPKPTIARITNTLVS
LGYLKQMPNSPKYMLDLGVLSLGYAALSNLSIRTTAHRFMEEMSMYAQAPVALAARDRLNMLYLDVVQTNSTMRRPIGST
LPLHNSSMGRACLAATPKQERYFLLEAIQKREPENWIEIKEKLDIAFDQYAEYGYCLSLGEWQQGINSVAVPLMSTKHGL
YVFNCGAPSYALSTEKLIEDIGPRLKYMVNSIQDALTESL

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=236, Percent_Identity=27.9661016949153, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1786468, Length=204, Percent_Identity=28.921568627451, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693096, Length=224, Percent_Identity=24.5535714285714, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789999, Length=233, Percent_Identity=27.0386266094421, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31589; Mature: 31458

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPSAETKNNDKTLNFDEIRLDPISHIHRENNPQFIASLARGLELLRCFSLQHQVLGNQE
CCCCCCCCCCCCCCCHHHEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LAKMTGLPKPTIARITNTLVSLGYLKQMPNSPKYMLDLGVLSLGYAALSNLSIRTTAHRF
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
MEEMSMYAQAPVALAARDRLNMLYLDVVQTNSTMRRPIGSTLPLHNSSMGRACLAATPKQ
HHHHHHHHHCCHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCH
ERYFLLEAIQKREPENWIEIKEKLDIAFDQYAEYGYCLSLGEWQQGINSVAVPLMSTKHG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCHHHHHHHHEECCCC
LYVFNCGAPSYALSTEKLIEDIGPRLKYMVNSIQDALTESL
EEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPSAETKNNDKTLNFDEIRLDPISHIHRENNPQFIASLARGLELLRCFSLQHQVLGNQE
CCCCCCCCCCCCCCHHHEEECHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
LAKMTGLPKPTIARITNTLVSLGYLKQMPNSPKYMLDLGVLSLGYAALSNLSIRTTAHRF
HHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHH
MEEMSMYAQAPVALAARDRLNMLYLDVVQTNSTMRRPIGSTLPLHNSSMGRACLAATPKQ
HHHHHHHHHCCHHHHHHHCCCEEEEEEECCCCHHHCCCCCCCCCCCCCCCCCHHHCCCCH
ERYFLLEAIQKREPENWIEIKEKLDIAFDQYAEYGYCLSLGEWQQGINSVAVPLMSTKHG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHCHHHHHHHHEECCCC
LYVFNCGAPSYALSTEKLIEDIGPRLKYMVNSIQDALTESL
EEEEECCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]