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The map label for this gene is caiB [H]

Identifier: 50084839

GI number: 50084839

Start: 1687510

End: 1688727

Strand: Direct

Name: caiB [H]

Synonym: ACIAD1683

Alternate gene names: 50084839

Gene position: 1687510-1688727 (Clockwise)

Preceding gene: 50084836

Following gene: 50084840

Centisome position: 46.89

GC content: 40.64

Gene sequence:

>1218_bases
ATGGGTGCTCTAGAAGGATTTCGTGTGCTTGATTTAAGTCGAGTGCTTGCAGGCCCTTGGTGTGGTCAGGTTTTGGCCGA
TTTAGGCGCAGAAGTAATTAAAGTCGAGCGCCCCAAACATGGAGATGATACCCGTGCTTGGGGCCCACCATGGATGAAGG
ATGATGAAGGTCGTGATACTCATGAAGCTGCATACTATCAGTCGACTAACCGTAATAAGCTTTCAGTTGCGATTGATATT
TCAACTCCAGAAGGTCAGGAAATCGTACGGGCACTCGCACTTGAATCAGATGTTTTAATTGAAAATTATAAATCAGGTTC
ATTAAAAAAATATGGTCTCGATTATGAAACACTGTCAAAGCTCAACCCAAAACTTGTTTATTGTTCAATTACTGGATTTG
GGCAAACTGGACCACGTGCACAAGAGCCAGGCTATGATTTTATTATTCAGGGTATGGGGGGATTAATGTCTGTCACTGGT
GAAAAAGATGATTTACCTGGCGGTGGCCCACAAAAATTAGGAATCGCATTTTCTGATATCGCAACAGGGTTATATTCGAC
CATCGCGATTCAAGCGGCCTTACTTAATCGTAATATCACGGGTTTGGGTCAATATATCGATATGGCCTTATTAGATGTAC
AGATTGCAACGCTGGCAAATCAAGGAATGAATTATCTGGCTTCAGGTAAAGTACCTGGCCGATATGGTAATGCTCATGCC
AATATTGTGCCTTATCAGGTGTTTAAGGCATCAGACCGAGATTTCATTATTGCCTGTGGCAATGACACGCAATTTATTCA
GTTGTGTCAGGCAATTGGATTGCCAGAGCTTCCTAATGATCCTAAATTTACCAGAAATGCAGATCGTATCAAGTATCGTG
AAGAAATCATCCATCTACTTTCAACGCATTTTTTAACTAAAACAGCCGATGAATGGGTTGGAATCATTCAAGCAGCTAAA
GTCCCAGTTGGATGTATTAATAATCTTGAACAAGCCTTTGAAGAACCACAAGTCATAGAAAGAAAAATGTTGGTAGATAT
GTCACATCCACAACGTGAGCATCTTAAAGTCATTGGTTCGCCTATTAAAATGTCGCGTACACCCGTTGAGTATAAAAATG
CACCTCCAATGCTTGGACAGCATACCGAAGAGATATTATCAAATATACTTTCTAGAGAAAGGTTTAGTGAGCTGAAATCA
AAAGGAATAATAGGATAA

Upstream 100 bases:

>100_bases
AAAAAGCATGTATATTGGTTTTTTATATCGCTATGCGAAATAAAATAAGTGCTTTGGCGAGTAAGATTAAATTTGGTTGA
AAGCAATAATAGGAAATGGT

Downstream 100 bases:

>100_bases
ATTCTTCAACGTTCATAGTAAAATAATTATACGTTTTATTACGTGCTTGTTTTGCTATGACAACAACAAATAGATTATAA
TTTTCGCAATGCGAAATATT

Product: L-carnitine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MGALEGFRVLDLSRVLAGPWCGQVLADLGAEVIKVERPKHGDDTRAWGPPWMKDDEGRDTHEAAYYQSTNRNKLSVAIDI
STPEGQEIVRALALESDVLIENYKSGSLKKYGLDYETLSKLNPKLVYCSITGFGQTGPRAQEPGYDFIIQGMGGLMSVTG
EKDDLPGGGPQKLGIAFSDIATGLYSTIAIQAALLNRNITGLGQYIDMALLDVQIATLANQGMNYLASGKVPGRYGNAHA
NIVPYQVFKASDRDFIIACGNDTQFIQLCQAIGLPELPNDPKFTRNADRIKYREEIIHLLSTHFLTKTADEWVGIIQAAK
VPVGCINNLEQAFEEPQVIERKMLVDMSHPQREHLKVIGSPIKMSRTPVEYKNAPPMLGQHTEEILSNILSRERFSELKS
KGIIG

Sequences:

>Translated_405_residues
MGALEGFRVLDLSRVLAGPWCGQVLADLGAEVIKVERPKHGDDTRAWGPPWMKDDEGRDTHEAAYYQSTNRNKLSVAIDI
STPEGQEIVRALALESDVLIENYKSGSLKKYGLDYETLSKLNPKLVYCSITGFGQTGPRAQEPGYDFIIQGMGGLMSVTG
EKDDLPGGGPQKLGIAFSDIATGLYSTIAIQAALLNRNITGLGQYIDMALLDVQIATLANQGMNYLASGKVPGRYGNAHA
NIVPYQVFKASDRDFIIACGNDTQFIQLCQAIGLPELPNDPKFTRNADRIKYREEIIHLLSTHFLTKTADEWVGIIQAAK
VPVGCINNLEQAFEEPQVIERKMLVDMSHPQREHLKVIGSPIKMSRTPVEYKNAPPMLGQHTEEILSNILSRERFSELKS
KGIIG
>Mature_404_residues
GALEGFRVLDLSRVLAGPWCGQVLADLGAEVIKVERPKHGDDTRAWGPPWMKDDEGRDTHEAAYYQSTNRNKLSVAIDIS
TPEGQEIVRALALESDVLIENYKSGSLKKYGLDYETLSKLNPKLVYCSITGFGQTGPRAQEPGYDFIIQGMGGLMSVTGE
KDDLPGGGPQKLGIAFSDIATGLYSTIAIQAALLNRNITGLGQYIDMALLDVQIATLANQGMNYLASGKVPGRYGNAHAN
IVPYQVFKASDRDFIIACGNDTQFIQLCQAIGLPELPNDPKFTRNADRIKYREEIIHLLSTHFLTKTADEWVGIIQAAKV
PVGCINNLEQAFEEPQVIERKMLVDMSHPQREHLKVIGSPIKMSRTPVEYKNAPPMLGQHTEEILSNILSRERFSELKSK
GIIG

Specific function: Unknown

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=403, Percent_Identity=42.6799007444169, Blast_Score=344, Evalue=8e-95,
Organism=Homo sapiens, GI300863124, Length=429, Percent_Identity=40.0932400932401, Blast_Score=331, Evalue=9e-91,
Organism=Homo sapiens, GI300863126, Length=403, Percent_Identity=37.2208436724566, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI13376042, Length=429, Percent_Identity=36.8298368298368, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI42794625, Length=416, Percent_Identity=27.1634615384615, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI266456254, Length=416, Percent_Identity=27.1634615384615, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI266458393, Length=276, Percent_Identity=28.9855072463768, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI266458397, Length=276, Percent_Identity=28.9855072463768, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI266458395, Length=144, Percent_Identity=34.7222222222222, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI42822893, Length=152, Percent_Identity=33.5526315789474, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI87082093, Length=396, Percent_Identity=35.8585858585859, Blast_Score=255, Evalue=3e-69,
Organism=Escherichia coli, GI1788717, Length=410, Percent_Identity=29.0243902439024, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786222, Length=420, Percent_Identity=27.6190476190476, Blast_Score=102, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI32564160, Length=354, Percent_Identity=26.271186440678, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115535051, Length=348, Percent_Identity=27.2988505747126, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24648431, Length=403, Percent_Identity=45.1612903225806, Blast_Score=360, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24585488, Length=412, Percent_Identity=24.7572815533981, Blast_Score=111, Evalue=7e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: NA

Molecular weight: Translated: 44588; Mature: 44456

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGALEGFRVLDLSRVLAGPWCGQVLADLGAEVIKVERPKHGDDTRAWGPPWMKDDEGRDT
CCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCH
HEAAYYQSTNRNKLSVAIDISTPEGQEIVRALALESDVLIENYKSGSLKKYGLDYETLSK
HHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCCCEECCCCHHHHHH
LNPKLVYCSITGFGQTGPRAQEPGYDFIIQGMGGLMSVTGEKDDLPGGGPQKLGIAFSDI
CCCEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCHHHCEEHHHH
ATGLYSTIAIQAALLNRNITGLGQYIDMALLDVQIATLANQGMNYLASGKVPGRYGNAHA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCC
NIVPYQVFKASDRDFIIACGNDTQFIQLCQAIGLPELPNDPKFTRNADRIKYREEIIHLL
CCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
STHFLTKTADEWVGIIQAAKVPVGCINNLEQAFEEPQVIERKMLVDMSHPQREHLKVIGS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCC
PIKMSRTPVEYKNAPPMLGQHTEEILSNILSRERFSELKSKGIIG
CHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GALEGFRVLDLSRVLAGPWCGQVLADLGAEVIKVERPKHGDDTRAWGPPWMKDDEGRDT
CCCCCCHHHHHHHHHCCCHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCH
HEAAYYQSTNRNKLSVAIDISTPEGQEIVRALALESDVLIENYKSGSLKKYGLDYETLSK
HHHHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHCCHHHHHCCCCCCCEECCCCHHHHHH
LNPKLVYCSITGFGQTGPRAQEPGYDFIIQGMGGLMSVTGEKDDLPGGGPQKLGIAFSDI
CCCEEEEEEEECCCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCHHHCEEHHHH
ATGLYSTIAIQAALLNRNITGLGQYIDMALLDVQIATLANQGMNYLASGKVPGRYGNAHA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCC
NIVPYQVFKASDRDFIIACGNDTQFIQLCQAIGLPELPNDPKFTRNADRIKYREEIIHLL
CCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
STHFLTKTADEWVGIIQAAKVPVGCINNLEQAFEEPQVIERKMLVDMSHPQREHLKVIGS
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHCC
PIKMSRTPVEYKNAPPMLGQHTEEILSNILSRERFSELKSKGIIG
CHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 8125343 [H]