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The map label for this gene is cfa [H]

Identifier: 50084790

GI number: 50084790

Start: 1628729

End: 1629784

Strand: Direct

Name: cfa [H]

Synonym: ACIAD1632

Alternate gene names: 50084790

Gene position: 1628729-1629784 (Clockwise)

Preceding gene: 50084789

Following gene: 50084791

Centisome position: 45.26

GC content: 40.44

Gene sequence:

>1056_bases
ATGGAATTTATTATTCAGCAGTCGCTCAAGCTGGTCGAAAGTGGTTTGGTGCCTGATCAGGCAATTCGTACCGCAATTCG
AGCATTGAGTAAAAAACGTTTAATTCAGGAAGGTCGTTACGACCCAGAGCAAGCGGCACAGCGCTATATGGATGTGCTCA
CCATGCTTAAAAATAGTGAAATTGCCATTGAAACAGACAAAGCCAATGAACAGCATTATGAGTTACCTACCGAATTTTTT
CAGACTGTACTCGGCAAGCGTCTAAAATATAGTGCGTGCTATTTTCCTCACGCCAAAACCACACTAGATGAGGCAGAAGA
ATTTTCATTACAGCTTTATAGTGAACGTGCCAAGCTTCAAAATGGTCAGAAGGTTTTAGAGTTAGGGTGTGGTTGGGGGT
CATTTACCTTATGGATGGCAGAGCATTATCCGCAATCTCACATTACCGGTGTTTCCAATTCTGCTACCCAGCGTCAGCAC
ATTCTCGAACAAGCGCAACAACGTGGGCTAAGTAATATCGAGATTGTCACTTGCGATGTCAACGTTCTTGAATTACAAAA
TGGTCATTTTGATCGGGTGGTATCGGTCGAAATGTTTGAGCATGTACGGAACTATCAGCGCTTATTTGAAAAAATACAAA
ACTGGCTGAAGCCAGAAGGTTTATTATGGTGTCATATTTTTTGCCACAGATTTTTGCATTATCCTTTTGAAATTAAGAAC
GAATATGATTGGATGTCAAAATATTTCTTTACAGGCGGATTAATGCCAGCAGTGTCTACATTTTTACATTTTCAACAGCA
TTTAGAATTGACCCAACAATGGCAATGGTCTGGAGAACATTATGAAAAAACGGCCAATGCATGGTTAAATAACATGGATA
CGCATGAAGCCCAGCTCAAGCCATTGTTTGAAAAAATTTATGCAAAAGACGCTGATGCTTGGTGGCAACGCTGGCGTATT
TTTTTCATGGCCTGTGCAGAACTGTTTGGTTTGGAACAAGGACAGGAATGGGTCATTGGTCACTTCTTGTTTAAAAAGAA
AGTGATTATAAGTTAA

Upstream 100 bases:

>100_bases
CAACAAGCGCTAAAAAATCGCGGACAAAATTATCGTGATTATCAGCAAAGAACATCAATGTTTATTCCACGAAAACCAAA
ACAATAGGCAGGCATACATT

Downstream 100 bases:

>100_bases
ATTAAAATTTAACTGAAACAGTAAGGAAGTATTGATTACGATATGTTGAAACCCCACCGCAATGATTCTTCAGGCCACCG
TGTAGCGGAAATCTTTAATC

Product: methyltransferase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MEFIIQQSLKLVESGLVPDQAIRTAIRALSKKRLIQEGRYDPEQAAQRYMDVLTMLKNSEIAIETDKANEQHYELPTEFF
QTVLGKRLKYSACYFPHAKTTLDEAEEFSLQLYSERAKLQNGQKVLELGCGWGSFTLWMAEHYPQSHITGVSNSATQRQH
ILEQAQQRGLSNIEIVTCDVNVLELQNGHFDRVVSVEMFEHVRNYQRLFEKIQNWLKPEGLLWCHIFCHRFLHYPFEIKN
EYDWMSKYFFTGGLMPAVSTFLHFQQHLELTQQWQWSGEHYEKTANAWLNNMDTHEAQLKPLFEKIYAKDADAWWQRWRI
FFMACAELFGLEQGQEWVIGHFLFKKKVIIS

Sequences:

>Translated_351_residues
MEFIIQQSLKLVESGLVPDQAIRTAIRALSKKRLIQEGRYDPEQAAQRYMDVLTMLKNSEIAIETDKANEQHYELPTEFF
QTVLGKRLKYSACYFPHAKTTLDEAEEFSLQLYSERAKLQNGQKVLELGCGWGSFTLWMAEHYPQSHITGVSNSATQRQH
ILEQAQQRGLSNIEIVTCDVNVLELQNGHFDRVVSVEMFEHVRNYQRLFEKIQNWLKPEGLLWCHIFCHRFLHYPFEIKN
EYDWMSKYFFTGGLMPAVSTFLHFQQHLELTQQWQWSGEHYEKTANAWLNNMDTHEAQLKPLFEKIYAKDADAWWQRWRI
FFMACAELFGLEQGQEWVIGHFLFKKKVIIS
>Mature_351_residues
MEFIIQQSLKLVESGLVPDQAIRTAIRALSKKRLIQEGRYDPEQAAQRYMDVLTMLKNSEIAIETDKANEQHYELPTEFF
QTVLGKRLKYSACYFPHAKTTLDEAEEFSLQLYSERAKLQNGQKVLELGCGWGSFTLWMAEHYPQSHITGVSNSATQRQH
ILEQAQQRGLSNIEIVTCDVNVLELQNGHFDRVVSVEMFEHVRNYQRLFEKIQNWLKPEGLLWCHIFCHRFLHYPFEIKN
EYDWMSKYFFTGGLMPAVSTFLHFQQHLELTQQWQWSGEHYEKTANAWLNNMDTHEAQLKPLFEKIYAKDADAWWQRWRI
FFMACAELFGLEQGQEWVIGHFLFKKKVIIS

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=278, Percent_Identity=29.8561151079137, Blast_Score=117, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI133904226, Length=276, Percent_Identity=25, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 41487; Mature: 41487

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFIIQQSLKLVESGLVPDQAIRTAIRALSKKRLIQEGRYDPEQAAQRYMDVLTMLKNSE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
IAIETDKANEQHYELPTEFFQTVLGKRLKYSACYFPHAKTTLDEAEEFSLQLYSERAKLQ
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHH
NGQKVLELGCGWGSFTLWMAEHYPQSHITGVSNSATQRQHILEQAQQRGLSNIEIVTCDV
CCHHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
NVLELQNGHFDRVVSVEMFEHVRNYQRLFEKIQNWLKPEGLLWCHIFCHRFLHYPFEIKN
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
EYDWMSKYFFTGGLMPAVSTFLHFQQHLELTQQWQWSGEHYEKTANAWLNNMDTHEAQLK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
PLFEKIYAKDADAWWQRWRIFFMACAELFGLEQGQEWVIGHFLFKKKVIIS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFIIQQSLKLVESGLVPDQAIRTAIRALSKKRLIQEGRYDPEQAAQRYMDVLTMLKNSE
CCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCC
IAIETDKANEQHYELPTEFFQTVLGKRLKYSACYFPHAKTTLDEAEEFSLQLYSERAKLQ
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHH
NGQKVLELGCGWGSFTLWMAEHYPQSHITGVSNSATQRQHILEQAQQRGLSNIEIVTCDV
CCHHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECC
NVLELQNGHFDRVVSVEMFEHVRNYQRLFEKIQNWLKPEGLLWCHIFCHRFLHYPFEIKN
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCC
EYDWMSKYFFTGGLMPAVSTFLHFQQHLELTQQWQWSGEHYEKTANAWLNNMDTHEAQLK
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCHHHHHH
PLFEKIYAKDADAWWQRWRIFFMACAELFGLEQGQEWVIGHFLFKKKVIIS
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]