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The map label for this gene is tauD [C]

Identifier: 50084754

GI number: 50084754

Start: 1584167

End: 1585075

Strand: Direct

Name: tauD [C]

Synonym: ACIAD1592

Alternate gene names: 50084754

Gene position: 1584167-1585075 (Clockwise)

Preceding gene: 50084753

Following gene: 50084755

Centisome position: 44.02

GC content: 42.68

Gene sequence:

>909_bases
ATGGCAGATTTATTAATAAAAAAACCAGTGAGTGAGTTAATCGATGTGATCCCTTTAGCAGGTCGTATCGGTGCGCAAAT
TAATGGTGTTGAATTATCTTCACACCTTAACCCTGAGGTCTTGAATCAAATTAGGCAATCATTGCTTGAACATAAAGTTA
TTTTTTTTCGTAATCAGGAACATTTAACCGATCAAGAACAGGAAAAGTTTGCCGAATTGCTTGGGCAACCTATTTCACAT
CCTACTGTTCCAGTGGCAGAGGGTTCGACTTATATATTTGAGCTTGATTCCCGTCATGACGGTCGTGCAGACGTTTGGCA
TACCGATGTTACCTTTGTATCAAATTATCCAAAAATTAGCATTCTAAGAGCGGTAACTACACCTCATCGAGGGGGCGATA
CCACATGGGCAAATACAGAGGCAGCCTATGATGAATTGCCAGAGCCGCTAAAGCTCCTTGCTAATCAGCTCCGTGCGATT
CACACCAATGATTTTGATTATGGTGGCTTTCGGCCTTCCGCAAGTGATGAAGTTGTAAAACGTCATCAAAAAATCTTTGC
TTCAACGGTCTATGAGGCGGAACACCCATTGGTCAGAGTACATCCTGAAACAGGTAAGCGAACCTTAATTTTAGGCCAAT
TTTTTAAACGATTTGTGGGTCTGACTGCTAAAGAGTCCAACAAGCTATTTGAAATTTTTCAAGATCGTATTACCAAACCA
GAAAACACGATTCGCTGGACGTGGAAGGACGGAGATGTCGCTATTTGGGACAACCGCGCCACTCAGCATTTAGCCGTCAA
TGATTATGGTAATGCCTTGCGTATCATGCGACGCGTTACGTTGGCAGGCGATGTTCCTGTTGATATCGATGGCAAAGCGA
GTAGGCAAATTAAGCCTTCTACGTCTTAA

Upstream 100 bases:

>100_bases
GAATAATTTTTCATAAATGCAGAAATGCTATGTAATTTTTGTTGCAGAATTTAAAGGGGGTAATTTCTAAACTCATATCA
TCAATGACGAGAACGATGAT

Downstream 100 bases:

>100_bases
GCCTCTAAGCAATACAACGCTGATTTATCAATAAAAATATGGAAGATATAATGAAACCATCAATTTTTAAAAAATTGATC
TTGCTGAGCTTATTGGCTTT

Product: alkylsulfatase

Products: Aminoacetaldehyde; CO2; H+; Sulfite; Succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MADLLIKKPVSELIDVIPLAGRIGAQINGVELSSHLNPEVLNQIRQSLLEHKVIFFRNQEHLTDQEQEKFAELLGQPISH
PTVPVAEGSTYIFELDSRHDGRADVWHTDVTFVSNYPKISILRAVTTPHRGGDTTWANTEAAYDELPEPLKLLANQLRAI
HTNDFDYGGFRPSASDEVVKRHQKIFASTVYEAEHPLVRVHPETGKRTLILGQFFKRFVGLTAKESNKLFEIFQDRITKP
ENTIRWTWKDGDVAIWDNRATQHLAVNDYGNALRIMRRVTLAGDVPVDIDGKASRQIKPSTS

Sequences:

>Translated_302_residues
MADLLIKKPVSELIDVIPLAGRIGAQINGVELSSHLNPEVLNQIRQSLLEHKVIFFRNQEHLTDQEQEKFAELLGQPISH
PTVPVAEGSTYIFELDSRHDGRADVWHTDVTFVSNYPKISILRAVTTPHRGGDTTWANTEAAYDELPEPLKLLANQLRAI
HTNDFDYGGFRPSASDEVVKRHQKIFASTVYEAEHPLVRVHPETGKRTLILGQFFKRFVGLTAKESNKLFEIFQDRITKP
ENTIRWTWKDGDVAIWDNRATQHLAVNDYGNALRIMRRVTLAGDVPVDIDGKASRQIKPSTS
>Mature_301_residues
ADLLIKKPVSELIDVIPLAGRIGAQINGVELSSHLNPEVLNQIRQSLLEHKVIFFRNQEHLTDQEQEKFAELLGQPISHP
TVPVAEGSTYIFELDSRHDGRADVWHTDVTFVSNYPKISILRAVTTPHRGGDTTWANTEAAYDELPEPLKLLANQLRAIH
TNDFDYGGFRPSASDEVVKRHQKIFASTVYEAEHPLVRVHPETGKRTLILGQFFKRFVGLTAKESNKLFEIFQDRITKPE
NTIRWTWKDGDVAIWDNRATQHLAVNDYGNALRIMRRVTLAGDVPVDIDGKASRQIKPSTS

Specific function: Catalyzes The Conversion Of Taurine And Alpha Ketoglutarate To Sulfite, Aminoacetaldehyde And Succinate. Required For The Utilization Of Taurine (2-Aminoethanesulfonic Acid) As An Alternative Sulfur Source. Pentane-Sulfonic Acid, 3- (N-Morpholino)Propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=280, Percent_Identity=39.2857142857143, Blast_Score=189, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6322971, Length=309, Percent_Identity=28.1553398058252, Blast_Score=100, Evalue=5e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: 1.14.11.17 [C]

Molecular weight: Translated: 34174; Mature: 34043

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADLLIKKPVSELIDVIPLAGRIGAQINGVELSSHLNPEVLNQIRQSLLEHKVIFFRNQE
CCCCHHHHHHHHHHHHHCCCHHHCCEECCEEECCCCCHHHHHHHHHHHHHCCEEEEECCH
HLTDQEQEKFAELLGQPISHPTVPVAEGSTYIFELDSRHDGRADVWHTDVTFVSNYPKIS
HCCCHHHHHHHHHHCCCCCCCCCEEECCCEEEEEECCCCCCCCCEEECCEEEECCCCCEE
ILRAVTTPHRGGDTTWANTEAAYDELPEPLKLLANQLRAIHTNDFDYGGFRPSASDEVVK
EEEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
RHQKIFASTVYEAEHPLVRVHPETGKRTLILGQFFKRFVGLTAKESNKLFEIFQDRITKP
HHHHHHHHHHHHCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
ENTIRWTWKDGDVAIWDNRATQHLAVNDYGNALRIMRRVTLAGDVPVDIDGKASRQIKPS
CCCEEEEEECCCEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
TS
CC
>Mature Secondary Structure 
ADLLIKKPVSELIDVIPLAGRIGAQINGVELSSHLNPEVLNQIRQSLLEHKVIFFRNQE
CCCHHHHHHHHHHHHHCCCHHHCCEECCEEECCCCCHHHHHHHHHHHHHCCEEEEECCH
HLTDQEQEKFAELLGQPISHPTVPVAEGSTYIFELDSRHDGRADVWHTDVTFVSNYPKIS
HCCCHHHHHHHHHHCCCCCCCCCEEECCCEEEEEECCCCCCCCCEEECCEEEECCCCCEE
ILRAVTTPHRGGDTTWANTEAAYDELPEPLKLLANQLRAIHTNDFDYGGFRPSASDEVVK
EEEEECCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
RHQKIFASTVYEAEHPLVRVHPETGKRTLILGQFFKRFVGLTAKESNKLFEIFQDRITKP
HHHHHHHHHHHHCCCCEEEECCCCCCEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCC
ENTIRWTWKDGDVAIWDNRATQHLAVNDYGNALRIMRRVTLAGDVPVDIDGKASRQIKPS
CCCEEEEEECCCEEEECCCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
TS
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Ascorbate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; O2; Taurine [C]

Specific reaction: 2-Oxoglutarate + O2 + Taurine --> Aminoacetaldehyde + CO2 + H+ + Sulfite + Succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]