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The map label for this gene is catI

Identifier: 50084623

GI number: 50084623

Start: 1446225

End: 1446911

Strand: Direct

Name: catI

Synonym: ACIAD1448

Alternate gene names: 50084623

Gene position: 1446225-1446911 (Clockwise)

Preceding gene: 50084622

Following gene: 50084624

Centisome position: 40.19

GC content: 54.44

Gene sequence:

>687_bases
ATGATAGATAAAAGTGCAGCGACCCTAACGGAAGCGCTCTCCCAGATCCACGACGGTGCCACCATCCTGATTGGTGGTTT
TGGAACAGCCGGCCAACCCGCCGAGCTGATTGACGGACTGATTGAACTAGGTCGCAAGAACCTGACCATCGTCAGCAACA
ACGCCGGCAATGGAGACTATGGACTGGCCAAGCTGCTAAAAACTGGCGCAGTTAAAAAGATCATCTGTTCCTTCCCACGT
CAGGCCGACTCCTACGTATTTGACGAGCTATACCGTGCGGGCAAAATTGAACTTGAAATCGTGCCGCAGGGCAATCTGGC
CTGTCGTATACAGGCCGCCGGCATGGGGCTGGGGCCGATCTACACCCCAACCGGTTTTGGCACTTTACTCGCAGAAGGTA
AACCTACCCTGAACTTTGATGGCAAAGACTACGTACTGGAAAACCCGATCAAGGCCGACTTTGCCCTGATCAAAGCCTAC
AAGGGCGACCGCTGGGGCAATCTGGTCTATCGCAAATCAGCACGAAACTTCGGCCCGATCATGGCCATGGCCGCCAACGT
GACCATCGCACAAGTGAGCGAAGTGGTGGCACTAGGAGAACTCGACCCGGAAAACGTGGTGACCCCAGGCATCTTTGTTC
AACACGTTGTACCAGTCCAATCTACCCCAGCAAGCGCTGCACCATAA

Upstream 100 bases:

>100_bases
ACGATAGCTAATATGTAAATAGAGATGACACTTCATCAGTGTTCATCTCTTACGTTTATGGTATTTCTTTATTTTCCGTT
TTCATCCAAAGGTTGATGAC

Downstream 100 bases:

>100_bases
GGAGATCGAGATGAGTTATCACAAACTGACCCGTGACCAGATCGCCCAGCGCGTTGCCCAAGACATTCCGGAAGGCTCCT
ATGTCAATCTTGGCATTGGC

Product: 3-oxoadipate CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MIDKSAATLTEALSQIHDGATILIGGFGTAGQPAELIDGLIELGRKNLTIVSNNAGNGDYGLAKLLKTGAVKKIICSFPR
QADSYVFDELYRAGKIELEIVPQGNLACRIQAAGMGLGPIYTPTGFGTLLAEGKPTLNFDGKDYVLENPIKADFALIKAY
KGDRWGNLVYRKSARNFGPIMAMAANVTIAQVSEVVALGELDPENVVTPGIFVQHVVPVQSTPASAAP

Sequences:

>Translated_228_residues
MIDKSAATLTEALSQIHDGATILIGGFGTAGQPAELIDGLIELGRKNLTIVSNNAGNGDYGLAKLLKTGAVKKIICSFPR
QADSYVFDELYRAGKIELEIVPQGNLACRIQAAGMGLGPIYTPTGFGTLLAEGKPTLNFDGKDYVLENPIKADFALIKAY
KGDRWGNLVYRKSARNFGPIMAMAANVTIAQVSEVVALGELDPENVVTPGIFVQHVVPVQSTPASAAP
>Mature_228_residues
MIDKSAATLTEALSQIHDGATILIGGFGTAGQPAELIDGLIELGRKNLTIVSNNAGNGDYGLAKLLKTGAVKKIICSFPR
QADSYVFDELYRAGKIELEIVPQGNLACRIQAAGMGLGPIYTPTGFGTLLAEGKPTLNFDGKDYVLENPIKADFALIKAY
KGDRWGNLVYRKSARNFGPIMAMAANVTIAQVSEVVALGELDPENVVTPGIFVQHVVPVQSTPASAAP

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family

Homologues:

Organism=Homo sapiens, GI4557817, Length=225, Percent_Identity=42.2222222222222, Blast_Score=186, Evalue=1e-47,
Organism=Homo sapiens, GI11545841, Length=228, Percent_Identity=42.1052631578947, Blast_Score=173, Evalue=1e-43,
Organism=Escherichia coli, GI1788551, Length=219, Percent_Identity=40.6392694063927, Blast_Score=181, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=227, Percent_Identity=41.4096916299559, Blast_Score=166, Evalue=9e-42,
Organism=Drosophila melanogaster, GI21358325, Length=224, Percent_Identity=41.9642857142857, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24655794, Length=224, Percent_Identity=41.9642857142857, Blast_Score=173, Evalue=8e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PCAI_ACIAD (Q43973)

Other databases:

- EMBL:   L05770
- EMBL:   AF009224
- EMBL:   CR543861
- EMBL:   CR543861
- PIR:   A44570
- RefSeq:   YP_046133.1
- RefSeq:   YP_046368.1
- ProteinModelPortal:   Q43973
- SMR:   Q43973
- STRING:   Q43973
- GeneID:   2879438
- GeneID:   2879924
- GenomeReviews:   CR543861_GR
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1448
- KEGG:   aci:ACIAD1704
- eggNOG:   COG1788
- HOGENOM:   HBG288750
- OMA:   FPRQVDS
- ProtClustDB:   CLSK751191
- BioCyc:   ASP62977:ACIAD1448-MONOMER
- BioCyc:   ASP62977:ACIAD1704-MONOMER
- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163
- PANTHER:   PTHR13707
- SMART:   SM00882
- TIGRFAMs:   TIGR02429

Pfam domain/function: PF01144 CoA_trans

EC number: =2.8.3.6

Molecular weight: Translated: 24074; Mature: 24074

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKSAATLTEALSQIHDGATILIGGFGTAGQPAELIDGLIELGRKNLTIVSNNAGNGDY
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCH
GLAKLLKTGAVKKIICSFPRQADSYVFDELYRAGKIELEIVPQGNLACRIQAAGMGLGPI
HHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCC
YTPTGFGTLLAEGKPTLNFDGKDYVLENPIKADFALIKAYKGDRWGNLVYRKSARNFGPI
CCCCCCCCEEECCCCCCCCCCCCEEECCCCHHHHHEEEHHCCCCCCCEEEECCCCCCCCH
MAMAANVTIAQVSEVVALGELDPENVVTPGIFVQHVVPVQSTPASAAP
HHHHHCCHHHHHHHHHHHCCCCHHHCCCCCHHEEEEECCCCCCCCCCC
>Mature Secondary Structure
MIDKSAATLTEALSQIHDGATILIGGFGTAGQPAELIDGLIELGRKNLTIVSNNAGNGDY
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCH
GLAKLLKTGAVKKIICSFPRQADSYVFDELYRAGKIELEIVPQGNLACRIQAAGMGLGPI
HHHHHHHHCHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCCCEEEEEEECCCCCCCC
YTPTGFGTLLAEGKPTLNFDGKDYVLENPIKADFALIKAYKGDRWGNLVYRKSARNFGPI
CCCCCCCCEEECCCCCCCCCCCCEEECCCCHHHHHEEEHHCCCCCCCEEEECCCCCCCCH
MAMAANVTIAQVSEVVALGELDPENVVTPGIFVQHVVPVQSTPASAAP
HHHHHCCHHHHHHHHHHHCCCCHHHCCCCCHHEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8063101; 8125318