BacMap

Definition	Acinetobacter sp. ADP1 chromosome, complete genome.
Accession	NC_005966
Length	3,598,621

Click here to switch to the map view.

The map label for this gene is benD

Identifier: 50084615

GI number: 50084615

Start: 1437222

End: 1438007

Strand: Direct

Name: benD

Synonym: ACIAD1439

Alternate gene names: 50084615

Gene position: 1437222-1438007 (Clockwise)

Preceding gene: 161349967

Following gene: 50084616

Centisome position: 39.94

GC content: 47.71

Gene sequence:

>786_bases
ATGAATTCGACACAACGTTTTGAACATAAAGTTGTCATTGTAACAGGTGCAGCTCAAGGCATTGGTCGTGGTGTTGCACT
ACGGATTGCCCAAGAGGGAGGGTGTCTGATATTGGCCGACCGTTCTGATCTGATTCAGGCGGTATTGGCTGAGATCAAAG
CCTTGGGCGCATTGGCAATTGCTGTTGAGACAGATTTGGAAACTTATGCTGGCGCAGAGTTGGTGGTATCACATGCAATT
GCCGAATACGGACGCATCGACGTGCTGATCAATAATGTCGGTGGTGCAATCTGGATGAAACCCTTTCAGGAGTTTTCAGA
AGAGGAAATTATTCAGGAGGTTCATCGCTCCCTATTTCCAGCGCTCTGGTGCTGCCGTGCAGTACTTCCAGAAATGCTAA
AACATCAACAGGGCACTATTGTAAATGTGTCGTCAATTGCGACACGAGGTATTCACCGAATTCCATATTCGGCTTCTAAA
GGCGGTGTAAATGCCTTAACGGCTTCACTTGCCTTTGAGCATGCCCAGCATGGTATTCGTGTGAATGCGGTTGCAACGGG
AGGAACTAAAGCACCGCCGCGTAAGATTCCACGTAATGCCCAGCCTTTATCGAAAAGTGAACAAGTCTGGATGCAACAAG
TGGTTGACCAAACCATTGATCGAAGCTTTTTAGGGCGTTATGGCAGTATTGATGAACAAGTCAATGCGATTACCTTTTTA
GCCTCAGATGAATCTTCTTACATCACGGGCAGCGTGCTTCCGGTGGGTGGAGGCGATCAGGGATGA

Upstream 100 bases:

>100_bases
GGTGGAAGCGGTGCGGAGCTGGCTGGATACGCAAGGTATTCAACCGGCGAACTTTTTATTTGAAAAATTCTCTGCCAACT
AACTCAAAACGGAGACCGAT

Downstream 100 bases:

>100_bases
TCTGATGGTCATTATTTAAAGGGAGACTGCAAGGAGGCATCATGACAACCCTGTTAAAAACATTGAAGCAAGATTGGTCG
TTATCGGCCACGATTGCAGG

Product: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase

Products: NA

Alternate protein names: 2-hydro-1,2-dihydroxybenzoate dehydrogenase; DHB dehydrogenase; Cis-1,2-dihydroxy-3,4-cyclohexadiene-1-carboxylate dehydrogenase; Cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MNSTQRFEHKVVIVTGAAQGIGRGVALRIAQEGGCLILADRSDLIQAVLAEIKALGALAIAVETDLETYAGAELVVSHAI
AEYGRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFPALWCCRAVLPEMLKHQQGTIVNVSSIATRGIHRIPYSASK
GGVNALTASLAFEHAQHGIRVNAVATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSFLGRYGSIDEQVNAITFL
ASDESSYITGSVLPVGGGDQG

Sequences:

>Translated_261_residues
MNSTQRFEHKVVIVTGAAQGIGRGVALRIAQEGGCLILADRSDLIQAVLAEIKALGALAIAVETDLETYAGAELVVSHAI
AEYGRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFPALWCCRAVLPEMLKHQQGTIVNVSSIATRGIHRIPYSASK
GGVNALTASLAFEHAQHGIRVNAVATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSFLGRYGSIDEQVNAITFL
ASDESSYITGSVLPVGGGDQG
>Mature_261_residues
MNSTQRFEHKVVIVTGAAQGIGRGVALRIAQEGGCLILADRSDLIQAVLAEIKALGALAIAVETDLETYAGAELVVSHAI
AEYGRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFPALWCCRAVLPEMLKHQQGTIVNVSSIATRGIHRIPYSASK
GGVNALTASLAFEHAQHGIRVNAVATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSFLGRYGSIDEQVNAITFL
ASDESSYITGSVLPVGGGDQG

Specific function: Degradation of 2-hydro-1,2-dihydroxy benzoate (DHB) to catechol

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family

Homologues:

Organism=Homo sapiens, GI32483357, Length=265, Percent_Identity=29.4339622641509, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI19923817, Length=261, Percent_Identity=27.9693486590038, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40254992, Length=257, Percent_Identity=30.3501945525292, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI7705925, Length=253, Percent_Identity=30.0395256916996, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI15277342, Length=269, Percent_Identity=27.5092936802974, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI66933014, Length=258, Percent_Identity=29.8449612403101, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI126723750, Length=267, Percent_Identity=28.0898876404494, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4504505, Length=226, Percent_Identity=32.3008849557522, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI10190704, Length=263, Percent_Identity=27.3764258555133, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=202, Percent_Identity=28.7128712871287, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI210032110, Length=199, Percent_Identity=28.1407035175879, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4503301, Length=230, Percent_Identity=24.7826086956522, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI5031737, Length=257, Percent_Identity=26.4591439688716, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI4758504, Length=190, Percent_Identity=28.4210526315789, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI126723191, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI87082100, Length=259, Percent_Identity=32.8185328185328, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=32.4324324324324, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=31.8897637795276, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787905, Length=256, Percent_Identity=28.125, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790717, Length=261, Percent_Identity=29.1187739463602, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI2367175, Length=271, Percent_Identity=29.8892988929889, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788459, Length=256, Percent_Identity=29.296875, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1789378, Length=262, Percent_Identity=26.3358778625954, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1786812, Length=264, Percent_Identity=28.4090909090909, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787820, Length=180, Percent_Identity=29.4444444444444, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789057, Length=261, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082160, Length=251, Percent_Identity=23.1075697211155, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994604, Length=262, Percent_Identity=33.969465648855, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI71994600, Length=261, Percent_Identity=32.5670498084291, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17559104, Length=270, Percent_Identity=31.8518518518519, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17562910, Length=269, Percent_Identity=30.8550185873606, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17561402, Length=263, Percent_Identity=27.3764258555133, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI193204405, Length=196, Percent_Identity=33.1632653061224, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17560150, Length=261, Percent_Identity=29.5019157088123, Blast_Score=87, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17562990, Length=269, Percent_Identity=29.368029739777, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=196, Percent_Identity=33.1632653061224, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=198, Percent_Identity=31.3131313131313, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560220, Length=199, Percent_Identity=31.6582914572864, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=276, Percent_Identity=29.3478260869565, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=261, Percent_Identity=28.735632183908, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI72000259, Length=265, Percent_Identity=29.811320754717, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=211, Percent_Identity=32.2274881516588, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=269, Percent_Identity=27.8810408921933, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565030, Length=271, Percent_Identity=28.0442804428044, Blast_Score=78, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17544670, Length=268, Percent_Identity=25.3731343283582, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=28.8389513108614, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17551412, Length=273, Percent_Identity=30.4029304029304, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560676, Length=265, Percent_Identity=23.7735849056604, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17538480, Length=271, Percent_Identity=29.1512915129151, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17563726, Length=189, Percent_Identity=28.042328042328, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=263, Percent_Identity=28.5171102661597, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=269, Percent_Identity=27.1375464684015, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=270, Percent_Identity=27.037037037037, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=26.4822134387352, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=167, Percent_Identity=29.3413173652695, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=167, Percent_Identity=29.3413173652695, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=26.6331658291457, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560332, Length=278, Percent_Identity=25.5395683453237, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=197, Percent_Identity=31.9796954314721, Blast_Score=81, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324126, Length=268, Percent_Identity=28.3582089552239, Blast_Score=66, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=196, Percent_Identity=32.1428571428571, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357041, Length=262, Percent_Identity=36.2595419847328, Blast_Score=124, Evalue=7e-29,
Organism=Drosophila melanogaster, GI28571526, Length=262, Percent_Identity=33.969465648855, Blast_Score=121, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24644339, Length=258, Percent_Identity=34.1085271317829, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=34.6303501945525, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=27.9527559055118, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=24.3243243243243, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644337, Length=265, Percent_Identity=32.4528301886792, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24643142, Length=257, Percent_Identity=29.1828793774319, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI18859837, Length=195, Percent_Identity=28.7179487179487, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24640492, Length=200, Percent_Identity=27, Blast_Score=68, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BEND_ACIAD (P07772)

Other databases:

- EMBL:   AF009224
- EMBL:   CR543861
- PIR:   S23480
- RefSeq:   YP_046125.1
- ProteinModelPortal:   P07772
- SMR:   P07772
- STRING:   P07772
- GeneID:   2880309
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1439
- NMPDR:   fig|62977.3.peg.797
- eggNOG:   COG1028
- HOGENOM:   HBG750976
- OMA:   EIQRTGG
- ProtClustDB:   PRK12823
- BioCyc:   ASP62977:ACIAD1439-MONOMER
- GO:   GO:0005488
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR19410
- PRINTS:   PR00081
- PRINTS:   PR00080

Pfam domain/function: PF00106 adh_short

EC number: =1.3.1.25

Molecular weight: Translated: 27982; Mature: 27982

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00061 ADH_SHORT

Important sites: ACT_SITE 156-156 BINDING 145-145

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSTQRFEHKVVIVTGAAQGIGRGVALRIAQEGGCLILADRSDLIQAVLAEIKALGALAI
CCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHEEE
AVETDLETYAGAELVVSHAIAEYGRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFP
EEECCHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHCCHHHHHHHHHHHHHH
ALWCCRAVLPEMLKHQQGTIVNVSSIATRGIHRIPYSASKGGVNALTASLAFEHAQHGIR
HHHHHHHHHHHHHHCCCCCEEEHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCEE
VNAVATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSFLGRYGSIDEQVNAITFL
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEE
ASDESSYITGSVLPVGGGDQG
ECCCCCEEEEEEEECCCCCCC
>Mature Secondary Structure
MNSTQRFEHKVVIVTGAAQGIGRGVALRIAQEGGCLILADRSDLIQAVLAEIKALGALAI
CCCCCCCCEEEEEEECCCCCCCCCEEEEEECCCCEEEEECHHHHHHHHHHHHHHHHHEEE
AVETDLETYAGAELVVSHAIAEYGRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFP
EEECCHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCEEEHHHHHCCHHHHHHHHHHHHHH
ALWCCRAVLPEMLKHQQGTIVNVSSIATRGIHRIPYSASKGGVNALTASLAFEHAQHGIR
HHHHHHHHHHHHHHCCCCCEEEHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHCCEE
VNAVATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSFLGRYGSIDEQVNAITFL
EEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCEEEEE
ASDESSYITGSVLPVGGGDQG
ECCCCCEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1740120