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The map label for this gene is cdsA [H]

Identifier: 50084553

GI number: 50084553

Start: 1370057

End: 1370881

Strand: Direct

Name: cdsA [H]

Synonym: ACIAD1375

Alternate gene names: 50084553

Gene position: 1370057-1370881 (Clockwise)

Preceding gene: 50084552

Following gene: 50084554

Centisome position: 38.07

GC content: 41.45

Gene sequence:

>825_bases
ATGTTAGAGCGGATTGTAACCGCGTTGGTGTTAGTAGCAGTTGTTTTAATTTGTATGTTTGCTACCCAATCGCATTATCC
AATGTTTGGATTAATGATTTTAGCAGCGGGAGTTGCTGGGTATGAGTGGTTTAAGCTTATGCCAAGGGAAACAAAAACAA
TTTTTAAGCCTAAAGCGTGGGCTTATGGCATTCTGGTTGCGATTGTTGCCGCGCTAGCATTATTCTATAGTGATGTTGCA
TTGTTGCTATGGTCTGCATCTATACTCACTTGGCTGGTCAGTGGTTTCTGGGTTAAGTCTTATCCTGAACATGATAATTG
GTATAATTCTACGTTATATATTGTAGGACTGATTTTAGTTAGTGCTGCGGTTACCGCGATATTTGAGGTTTGGCAGACAT
CTCCATGGTGGCTAATGTATCTGTTCTTATTGGTATGGGGAGCAGATAGCGGGGCTTATTTCGTCGGGCGTAAATTTGGC
AAGAACAAGCTCGCACCTACAGTGAGCCCTAACAAATCTGTAGAGGGTTTAATTGGTGGAGTGGTCGTTACTACAATCTT
GATCATCGTGGTAGAAACGATCTATCTTGATTTAACAATCTCACAGCATATTTTATTTCTCCTGTTATCTCTGCTTACTG
TATTTTCTTCTGTATTAGGTGATCTGTTTGAGTCAATGGTCAAGCGTCGCGCTGGCATTAAAGATTCTGGGCGCATTTTA
CCAGGTCATGGTGGTGTGCTGGATCGTATTGACTCATTATTGGCTGCGGCTCCTGTATTTGCGGCAGGAATCTACTTATT
GAAACTCATTGGTGTAGATTTATAA

Upstream 100 bases:

>100_bases
TAGATGAGTTTGACCATGCTTTAGCAGTGTTTGCTGGACGCGAACGCCGTTTTGGAAAAACTTCAGAGCAAATCCAACAA
GATAAAATTGAGAATTAATA

Downstream 100 bases:

>100_bases
ATGACACAATCTGTTTGTATATTGGGTGTAACGGGTTCAATCGGACAAAGCACTTTAAAAGTTTTAGCGCAGCATCCAGA
TAAGTATTCGATTTACGCCA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MLERIVTALVLVAVVLICMFATQSHYPMFGLMILAAGVAGYEWFKLMPRETKTIFKPKAWAYGILVAIVAALALFYSDVA
LLLWSASILTWLVSGFWVKSYPEHDNWYNSTLYIVGLILVSAAVTAIFEVWQTSPWWLMYLFLLVWGADSGAYFVGRKFG
KNKLAPTVSPNKSVEGLIGGVVVTTILIIVVETIYLDLTISQHILFLLLSLLTVFSSVLGDLFESMVKRRAGIKDSGRIL
PGHGGVLDRIDSLLAAAPVFAAGIYLLKLIGVDL

Sequences:

>Translated_274_residues
MLERIVTALVLVAVVLICMFATQSHYPMFGLMILAAGVAGYEWFKLMPRETKTIFKPKAWAYGILVAIVAALALFYSDVA
LLLWSASILTWLVSGFWVKSYPEHDNWYNSTLYIVGLILVSAAVTAIFEVWQTSPWWLMYLFLLVWGADSGAYFVGRKFG
KNKLAPTVSPNKSVEGLIGGVVVTTILIIVVETIYLDLTISQHILFLLLSLLTVFSSVLGDLFESMVKRRAGIKDSGRIL
PGHGGVLDRIDSLLAAAPVFAAGIYLLKLIGVDL
>Mature_274_residues
MLERIVTALVLVAVVLICMFATQSHYPMFGLMILAAGVAGYEWFKLMPRETKTIFKPKAWAYGILVAIVAALALFYSDVA
LLLWSASILTWLVSGFWVKSYPEHDNWYNSTLYIVGLILVSAAVTAIFEVWQTSPWWLMYLFLLVWGADSGAYFVGRKFG
KNKLAPTVSPNKSVEGLIGGVVVTTILIIVVETIYLDLTISQHILFLLLSLLTVFSSVLGDLFESMVKRRAGIKDSGRIL
PGHGGVLDRIDSLLAAAPVFAAGIYLLKLIGVDL

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=126, Percent_Identity=55.5555555555556, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1787677, Length=112, Percent_Identity=45.5357142857143, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30166; Mature: 30166

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]