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The map label for this gene is frr

Identifier: 50084551

GI number: 50084551

Start: 1368746

End: 1369300

Strand: Direct

Name: frr

Synonym: ACIAD1373

Alternate gene names: 50084551

Gene position: 1368746-1369300 (Clockwise)

Preceding gene: 50084550

Following gene: 50084552

Centisome position: 38.04

GC content: 41.26

Gene sequence:

>555_bases
ATGATTAACGATCTCAAGAAAGACAGCGAACAGCGTATGCAAAAGACTCTAGAGTCTCTAGAGCAGGGTTTTGCGAAAGT
TCGTACAGGCCGTGCACACCCATCTATATTAAATGGTGTTATGGTTCCTTACTATGGTTCAGATGTGCCGTTGAATCAGG
TTGCAAACGTAGGTATAGAAGATTCGCGTACCTTGGTGGTGCAGCCATTTGAGCGCACAATGGTTTCGGCAATTGATAAA
GCGATTCGTGAAAGTGACTTGGGATTAAACCCTATTACGGCTGATTCTATTCGTGTGCCATTACCTGCACTTACTGAAGA
AACACGTCGTGATATGCAAAAAGTTGCACGTTCTGAAGCTGAAAATGCAAAAGTTGCGATTCGTAATATTCGTCGTGATG
TTTTAGGTGATCTTAAAAGCTTGTTGAAAGATAAAGAAATCTCTGAAGATGATGAGCGTCGTGCAGGTGATGATATTCAA
AAAATTACCGATAAATATGTTGCTGAAGTAGACAAGCGCTTAGCAGCAAAAGAAGCAGAACTGATGAAGGTCTAA

Upstream 100 bases:

>100_bases
GGTACACACGTCACTAAATAATGACGTGTAACTCAAAGCTCTTTATACTACCCCACTAATTTAGTTTTACACCTTTGAAT
GAATAAGTAAGGAAGATCAT

Downstream 100 bases:

>100_bases
TTTGATGACCCTGTCTGAAGAAAGTCATCTTCCAAAACATGTTGCCATCATTATGGATGGCAACAATCGTTTTGCTAAAA
AAAATCAGATGCAAAAAGGA

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MINDLKKDSEQRMQKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGIEDSRTLVVQPFERTMVSAIDK
AIRESDLGLNPITADSIRVPLPALTEETRRDMQKVARSEAENAKVAIRNIRRDVLGDLKSLLKDKEISEDDERRAGDDIQ
KITDKYVAEVDKRLAAKEAELMKV

Sequences:

>Translated_184_residues
MINDLKKDSEQRMQKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGIEDSRTLVVQPFERTMVSAIDK
AIRESDLGLNPITADSIRVPLPALTEETRRDMQKVARSEAENAKVAIRNIRRDVLGDLKSLLKDKEISEDDERRAGDDIQ
KITDKYVAEVDKRLAAKEAELMKV
>Mature_184_residues
MINDLKKDSEQRMQKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGIEDSRTLVVQPFERTMVSAIDK
AIRESDLGLNPITADSIRVPLPALTEETRRDMQKVARSEAENAKVAIRNIRRDVLGDLKSLLKDKEISEDDERRAGDDIQ
KITDKYVAEVDKRLAAKEAELMKV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=32.9545454545455, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI291042689, Length=136, Percent_Identity=36.0294117647059, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=56.5217391304348, Blast_Score=212, Evalue=1e-56,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=27.0114942528736, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_ACIAD (Q6FCH2)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_046061.1
- ProteinModelPortal:   Q6FCH2
- SMR:   Q6FCH2
- STRING:   Q6FCH2
- GeneID:   2878598
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1373
- NMPDR:   fig|62977.3.peg.605
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q6FCH2
- ProtClustDB:   PRK00083
- BioCyc:   ASP62977:ACIAD1373-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20661; Mature: 20661

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINDLKKDSEQRMQKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGIE
CCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCC
DSRTLVVQPFERTMVSAIDKAIRESDLGLNPITADSIRVPLPALTEETRRDMQKVARSEA
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ENAKVAIRNIRRDVLGDLKSLLKDKEISEDDERRAGDDIQKITDKYVAEVDKRLAAKEAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LMKV
HHCC
>Mature Secondary Structure
MINDLKKDSEQRMQKTLESLEQGFAKVRTGRAHPSILNGVMVPYYGSDVPLNQVANVGIE
CCCCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCCCCHHHHHCCCCC
DSRTLVVQPFERTMVSAIDKAIRESDLGLNPITADSIRVPLPALTEETRRDMQKVARSEA
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ENAKVAIRNIRRDVLGDLKSLLKDKEISEDDERRAGDDIQKITDKYVAEVDKRLAAKEAE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LMKV
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA