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The map label for this gene is ktrB [H]

Identifier: 50084534

GI number: 50084534

Start: 1350489

End: 1351826

Strand: Reverse

Name: ktrB [H]

Synonym: ACIAD1355

Alternate gene names: 50084534

Gene position: 1351826-1350489 (Counterclockwise)

Preceding gene: 50084535

Following gene: 50084531

Centisome position: 37.57

GC content: 37.97

Gene sequence:

>1338_bases
ATGAAAAAACAAAAAATTAATCAAAAAACATTTAATTTAAGCCCACCGTCAATGCTGGCGCTGGGTTTTTTAAGCTTCAT
TGTCGCAGGTACGTTACTGCTCAAACTTCCTATTTCGAATAATGGTCACTTAAGCTGGATGGATGCCTTTTTTACCGCGA
CATCCGCGGTGACCATTACAGGACTTTCTGTCATAAATATTGGACAATCCCTTACCCATGTCGGTCAAATCATTTTATTG
TTTTTGATTCAATGTGGGGGGCTAGGTTTTATGACCTTTGCCATACTGGCTGCGCTTAGTTTAGCTCCCCAACTTGGCTT
AAAACAGCAGCTCATGGCTCAAGATTCTATGGGTCAAACCAGTCTATCTAAAGTCACTTTTATTGCACAGGCCGTATTCA
TTTATACCCTAATCTTTGAATTAATGGGGACTTGTATCTTAACGTTTGCATGGATGAATCAATTCGGATTTTTTCATGCA
TTGTATTATGCTTTTTTTTATAGTATTTCAGCTTTCAATAATGCAGGATTTTCATTATTTCCAAATAATCTAATGAATTT
TCAGACGCACTATATTGCCTGTTTAACCATCAGCTTTCTCTATATCTTAGGCGGTCTTGGCTTTCTGGTGATCATGGATA
TTAAAGAGCGTAAACGCTGGAAAAAACTCAGTCCTAATAGCAAAATTGTGATCATTAGTATCGCTATTTTGAACACCTCT
GCTTTTCTTATTATCTGGTTATTAGAAGTCAATAATCCCCTCACCTTATACTCGATGAGCTTTAGCGAGCAAGCACTCAA
TGCATGGTTTCAAGCGACTGTTCCAAGGTCATCTGGATTCAATACCATTGATATTGCATCTATGAACAATAGTTCCACCC
TTTTGACCATGTTTCTTATGTTTATTGGCGGAGGTTCACTCAGTACCGCTGGCGGGATAAAAGTAGGAACCTTTGTAATT
CTAGTATTTAGTGTGATTGCTTTTTTAAAGCGTCATGATGAAGTTCGGATCTTCAATCACTCTATCTCCTATGAAAATAC
ATTTAAAGCCTTAGCCGTTGTCGTGATTACCCTGATTTTGATCTTTATCGGCTTTTTTAGCATTCTGATTCTTGAGCCAC
ACAAAAATTTTCTGGATCTGTTTTTTGAAATAGTATCGGCGGCATGTACTGTCGGATTATCAAGAGGTATTACCCCTCAG
TTAAATAATAGTAGTCTTTTTGTGCTGTCATTATTGATGTATGCGGGACGACTTGGGCCTTTAACGCTGGCTTATCTGAT
TGCAACACCAAAGAAAAGCCGACTTAAACATCCGTCGGCTGATATTCAAATTGGTTAA

Upstream 100 bases:

>100_bases
TATGAACCAGATCCTACTTGTCCTGTTCAGTCAAAAGATATTCTGATTCTTGAAGGCCACATTGATCAGTTAAAGAAACT
ATCTCGGCGTTTTTTACCTC

Downstream 100 bases:

>100_bases
TGGTTGAGGAGTGTTCTACACTCCTCAAAGATATCCATCTGACCGTTCAGATCAATACCAGTTCATCAGTGAAACGCCCA
AACCAACATAAGTTGCACGA

Product: potassium uptake protein (TrkH)

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MKKQKINQKTFNLSPPSMLALGFLSFIVAGTLLLKLPISNNGHLSWMDAFFTATSAVTITGLSVINIGQSLTHVGQIILL
FLIQCGGLGFMTFAILAALSLAPQLGLKQQLMAQDSMGQTSLSKVTFIAQAVFIYTLIFELMGTCILTFAWMNQFGFFHA
LYYAFFYSISAFNNAGFSLFPNNLMNFQTHYIACLTISFLYILGGLGFLVIMDIKERKRWKKLSPNSKIVIISIAILNTS
AFLIIWLLEVNNPLTLYSMSFSEQALNAWFQATVPRSSGFNTIDIASMNNSSTLLTMFLMFIGGGSLSTAGGIKVGTFVI
LVFSVIAFLKRHDEVRIFNHSISYENTFKALAVVVITLILIFIGFFSILILEPHKNFLDLFFEIVSAACTVGLSRGITPQ
LNNSSLFVLSLLMYAGRLGPLTLAYLIATPKKSRLKHPSADIQIG

Sequences:

>Translated_445_residues
MKKQKINQKTFNLSPPSMLALGFLSFIVAGTLLLKLPISNNGHLSWMDAFFTATSAVTITGLSVINIGQSLTHVGQIILL
FLIQCGGLGFMTFAILAALSLAPQLGLKQQLMAQDSMGQTSLSKVTFIAQAVFIYTLIFELMGTCILTFAWMNQFGFFHA
LYYAFFYSISAFNNAGFSLFPNNLMNFQTHYIACLTISFLYILGGLGFLVIMDIKERKRWKKLSPNSKIVIISIAILNTS
AFLIIWLLEVNNPLTLYSMSFSEQALNAWFQATVPRSSGFNTIDIASMNNSSTLLTMFLMFIGGGSLSTAGGIKVGTFVI
LVFSVIAFLKRHDEVRIFNHSISYENTFKALAVVVITLILIFIGFFSILILEPHKNFLDLFFEIVSAACTVGLSRGITPQ
LNNSSLFVLSLLMYAGRLGPLTLAYLIATPKKSRLKHPSADIQIG
>Mature_445_residues
MKKQKINQKTFNLSPPSMLALGFLSFIVAGTLLLKLPISNNGHLSWMDAFFTATSAVTITGLSVINIGQSLTHVGQIILL
FLIQCGGLGFMTFAILAALSLAPQLGLKQQLMAQDSMGQTSLSKVTFIAQAVFIYTLIFELMGTCILTFAWMNQFGFFHA
LYYAFFYSISAFNNAGFSLFPNNLMNFQTHYIACLTISFLYILGGLGFLVIMDIKERKRWKKLSPNSKIVIISIAILNTS
AFLIIWLLEVNNPLTLYSMSFSEQALNAWFQATVPRSSGFNTIDIASMNNSSTLLTMFLMFIGGGSLSTAGGIKVGTFVI
LVFSVIAFLKRHDEVRIFNHSISYENTFKALAVVVITLILIFIGFFSILILEPHKNFLDLFFEIVSAACTVGLSRGITPQ
LNNSSLFVLSLLMYAGRLGPLTLAYLIATPKKSRLKHPSADIQIG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 49069; Mature: 49069

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKQKINQKTFNLSPPSMLALGFLSFIVAGTLLLKLPISNNGHLSWMDAFFTATSAVTIT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHEEE
GLSVINIGQSLTHVGQIILLFLIQCGGLGFMTFAILAALSLAPQLGLKQQLMAQDSMGQT
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
SLSKVTFIAQAVFIYTLIFELMGTCILTFAWMNQFGFFHALYYAFFYSISAFNNAGFSLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEC
PNNLMNFQTHYIACLTISFLYILGGLGFLVIMDIKERKRWKKLSPNSKIVIISIAILNTS
CCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHCCCCCCCEEEEEEEECCCC
AFLIIWLLEVNNPLTLYSMSFSEQALNAWFQATVPRSSGFNTIDIASMNNSSTLLTMFLM
CEEEEEEEECCCCEEEEEECHHHHHHHHHHHEECCCCCCCCEEEEEECCCCHHHHHHHHH
FIGGGSLSTAGGIKVGTFVILVFSVIAFLKRHDEVRIFNHSISYENTFKALAVVVITLIL
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
IFIGFFSILILEPHKNFLDLFFEIVSAACTVGLSRGITPQLNNSSLFVLSLLMYAGRLGP
HHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCH
LTLAYLIATPKKSRLKHPSADIQIG
HHHHHHHCCCCHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKQKINQKTFNLSPPSMLALGFLSFIVAGTLLLKLPISNNGHLSWMDAFFTATSAVTIT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHEEE
GLSVINIGQSLTHVGQIILLFLIQCGGLGFMTFAILAALSLAPQLGLKQQLMAQDSMGQT
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCH
SLSKVTFIAQAVFIYTLIFELMGTCILTFAWMNQFGFFHALYYAFFYSISAFNNAGFSLF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEC
PNNLMNFQTHYIACLTISFLYILGGLGFLVIMDIKERKRWKKLSPNSKIVIISIAILNTS
CCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEEHHHHHHHHCCCCCCCEEEEEEEECCCC
AFLIIWLLEVNNPLTLYSMSFSEQALNAWFQATVPRSSGFNTIDIASMNNSSTLLTMFLM
CEEEEEEEECCCCEEEEEECHHHHHHHHHHHEECCCCCCCCEEEEEECCCCHHHHHHHHH
FIGGGSLSTAGGIKVGTFVILVFSVIAFLKRHDEVRIFNHSISYENTFKALAVVVITLIL
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
IFIGFFSILILEPHKNFLDLFFEIVSAACTVGLSRGITPQLNNSSLFVLSLLMYAGRLGP
HHHHHHHHEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCH
LTLAYLIATPKKSRLKHPSADIQIG
HHHHHHHCCCCHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]