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The map label for this gene is argD [H]

Identifier: 50084469

GI number: 50084469

Start: 1286124

End: 1287335

Strand: Direct

Name: argD [H]

Synonym: ACIAD1284

Alternate gene names: 50084469

Gene position: 1286124-1287335 (Clockwise)

Preceding gene: 50084467

Following gene: 50084470

Centisome position: 35.74

GC content: 44.14

Gene sequence:

>1212_bases
ATGAGCATACATCATCTGAATCGTCAGGACTTTAATCAATTTATGGTGCCAGTATTTGCACCAGCTCAATTCATTCCTGT
ACGTGGCCAAGGTTCTCGTCTTTGGGATCAGGACGACAAAGAATATATCGATTTTGCGGGGGGGATTGCAGTCAATGCTT
TAGGTCATGCACATCCTATTGCGGTCAATGCTTTAATCGAACAAGGTCAAAAACTTTGGCACATTGGTAACGGTTATACC
AATGAACCTGTGTTGGCTTTGGCGAAACAATTGGTCGATCACACTTTTGCCGATAAGGTATTTTTCTGTAATTCAGGCGC
CGAGGCAAATGAGGCTGCGCTTAAGTTAGCGCGCAAGATTGGGCTATCTAAAAATAAAAGTAAAATCGTGGCTTTTAATA
ATGCCTTTCATGGCCGTACGTTATTTACCGTAACCGCAGGCGGACAGCCAAAATATTCTCAAGATTTTGCCCCTTTACCC
GCAGGGATTGAACATGTGGCATTCAATGATTTAAATGCAGCGGCGGCAGTGATTGATGATCAAACCTGCGCTGTGATTGT
GGAACCGATTCAGGGCGAGGGTGGTGTCCTTCCAGCCGATCTTGAGTTTTTAAAAGGTTTGCGTCGTTTGTGTGATGAAA
CAGGTGCGGTATTAATTTTTGATGAAGTTCAAACTGGCGTAGGACGTACAGGTGCATTGTATGCCTATATGAATACGGGT
GTTGTCCCCGATATTTTGACGACTGCCAAAGCATTGGGTGGTGGTTTTCCTATTGGCGCCATGATCACGACAGATCAATA
TGCCAATGTGTTTGTGGTGGGTGACCATGGTACAACCTATGGAGGTAATCCTCTGGCCTGTGCGGTTGCTGGGGCTGTCT
TCAATTTTATTAACACGGCCGATGTTTTAGATGGTGTCAAACAACGTTCACAGCAGTTTATTGATGAACTTGAGCAACTC
AATCATACCTATGCTGTATTTCAGGAAATTCGTGGGCAAGGTCTATTGCTAGGCTGTGTACTCAGACCTGAATATGCAGG
TAAAGCAAAAGACATTGTCACATTAGCAGGTGCCGAAGGGCTTCTTGCCTTGATTGCTGGGCCAAATGTAGTGCGTTTTA
CACCTTCTTTAGTGATTTCTGAACAAGAAATTTCAGAAGGTTTACAACGCTTTGGTCGAGCTCTGTCTCAATTTGTGGCT
GTACATCAATAA

Upstream 100 bases:

>100_bases
CAATTTAATCATAATAACAACTTTTTTAAATCAAATTGATTTTTCATACTAGTCAATATCAAAGAACACGTAACAGACCA
AATTGGATTACGAGGGCATC

Downstream 100 bases:

>100_bases
AAGGTCGCTCATTATGTTGATCGTTAGACATGCAGAGTTCCGCGATCTGGATGATATCTTCATCTTGGCAGAGAAATCTG
GCGTCGGCTTAACCTCTTTG

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 403; Mature: 402

Protein sequence:

>403_residues
MSIHHLNRQDFNQFMVPVFAPAQFIPVRGQGSRLWDQDDKEYIDFAGGIAVNALGHAHPIAVNALIEQGQKLWHIGNGYT
NEPVLALAKQLVDHTFADKVFFCNSGAEANEAALKLARKIGLSKNKSKIVAFNNAFHGRTLFTVTAGGQPKYSQDFAPLP
AGIEHVAFNDLNAAAAVIDDQTCAVIVEPIQGEGGVLPADLEFLKGLRRLCDETGAVLIFDEVQTGVGRTGALYAYMNTG
VVPDILTTAKALGGGFPIGAMITTDQYANVFVVGDHGTTYGGNPLACAVAGAVFNFINTADVLDGVKQRSQQFIDELEQL
NHTYAVFQEIRGQGLLLGCVLRPEYAGKAKDIVTLAGAEGLLALIAGPNVVRFTPSLVISEQEISEGLQRFGRALSQFVA
VHQ

Sequences:

>Translated_403_residues
MSIHHLNRQDFNQFMVPVFAPAQFIPVRGQGSRLWDQDDKEYIDFAGGIAVNALGHAHPIAVNALIEQGQKLWHIGNGYT
NEPVLALAKQLVDHTFADKVFFCNSGAEANEAALKLARKIGLSKNKSKIVAFNNAFHGRTLFTVTAGGQPKYSQDFAPLP
AGIEHVAFNDLNAAAAVIDDQTCAVIVEPIQGEGGVLPADLEFLKGLRRLCDETGAVLIFDEVQTGVGRTGALYAYMNTG
VVPDILTTAKALGGGFPIGAMITTDQYANVFVVGDHGTTYGGNPLACAVAGAVFNFINTADVLDGVKQRSQQFIDELEQL
NHTYAVFQEIRGQGLLLGCVLRPEYAGKAKDIVTLAGAEGLLALIAGPNVVRFTPSLVISEQEISEGLQRFGRALSQFVA
VHQ
>Mature_402_residues
SIHHLNRQDFNQFMVPVFAPAQFIPVRGQGSRLWDQDDKEYIDFAGGIAVNALGHAHPIAVNALIEQGQKLWHIGNGYTN
EPVLALAKQLVDHTFADKVFFCNSGAEANEAALKLARKIGLSKNKSKIVAFNNAFHGRTLFTVTAGGQPKYSQDFAPLPA
GIEHVAFNDLNAAAAVIDDQTCAVIVEPIQGEGGVLPADLEFLKGLRRLCDETGAVLIFDEVQTGVGRTGALYAYMNTGV
VPDILTTAKALGGGFPIGAMITTDQYANVFVVGDHGTTYGGNPLACAVAGAVFNFINTADVLDGVKQRSQQFIDELEQLN
HTYAVFQEIRGQGLLLGCVLRPEYAGKAKDIVTLAGAEGLLALIAGPNVVRFTPSLVISEQEISEGLQRFGRALSQFVAV
HQ

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=35.6200527704486, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI284507298, Length=302, Percent_Identity=36.0927152317881, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI13994255, Length=426, Percent_Identity=28.6384976525822, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI37574042, Length=416, Percent_Identity=26.9230769230769, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI226442705, Length=416, Percent_Identity=26.2019230769231, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226442709, Length=381, Percent_Identity=27.0341207349081, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI24119277, Length=392, Percent_Identity=27.2959183673469, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI188536080, Length=436, Percent_Identity=23.8532110091743, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679950, Length=436, Percent_Identity=23.8532110091743, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI38679946, Length=436, Percent_Identity=23.8532110091743, Blast_Score=89, Evalue=7e-18,
Organism=Escherichia coli, GI1788044, Length=398, Percent_Identity=67.0854271356784, Blast_Score=560, Evalue=1e-161,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=59.1939546599496, Blast_Score=507, Evalue=1e-145,
Organism=Escherichia coli, GI145693181, Length=322, Percent_Identity=40.0621118012422, Blast_Score=208, Evalue=5e-55,
Organism=Escherichia coli, GI1789016, Length=402, Percent_Identity=33.8308457711443, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1787560, Length=400, Percent_Identity=33.5, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786349, Length=307, Percent_Identity=34.5276872964169, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786991, Length=322, Percent_Identity=32.2981366459627, Blast_Score=118, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25144271, Length=388, Percent_Identity=32.4742268041237, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=28.9351851851852, Blast_Score=174, Evalue=8e-44,
Organism=Caenorhabditis elegans, GI25144274, Length=279, Percent_Identity=32.9749103942652, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71992977, Length=433, Percent_Identity=27.7136258660508, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17541228, Length=420, Percent_Identity=25.7142857142857, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71981843, Length=153, Percent_Identity=31.3725490196078, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=408, Percent_Identity=41.421568627451, Blast_Score=296, Evalue=3e-81,
Organism=Saccharomyces cerevisiae, GI6323470, Length=406, Percent_Identity=31.2807881773399, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6324386, Length=363, Percent_Identity=28.9256198347107, Blast_Score=112, Evalue=7e-26,
Organism=Saccharomyces cerevisiae, GI6321456, Length=374, Percent_Identity=26.4705882352941, Blast_Score=84, Evalue=5e-17,
Organism=Drosophila melanogaster, GI21357415, Length=385, Percent_Identity=34.8051948051948, Blast_Score=211, Evalue=5e-55,
Organism=Drosophila melanogaster, GI28574759, Length=411, Percent_Identity=30.4136253041363, Blast_Score=161, Evalue=6e-40,
Organism=Drosophila melanogaster, GI161085790, Length=427, Percent_Identity=29.5081967213115, Blast_Score=161, Evalue=7e-40,
Organism=Drosophila melanogaster, GI21356575, Length=419, Percent_Identity=27.6849642004773, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI281366494, Length=304, Percent_Identity=27.3026315789474, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667139, Length=304, Percent_Identity=27.3026315789474, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24667143, Length=304, Percent_Identity=27.3026315789474, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43176; Mature: 43044

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIHHLNRQDFNQFMVPVFAPAQFIPVRGQGSRLWDQDDKEYIDFAGGIAVNALGHAHPI
CCCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCCCCCCHHHHHHCCCEEEECCCCCCHH
AVNALIEQGQKLWHIGNGYTNEPVLALAKQLVDHTFADKVFFCNSGAEANEAALKLARKI
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHH
GLSKNKSKIVAFNNAFHGRTLFTVTAGGQPKYSQDFAPLPAGIEHVAFNDLNAAAAVIDD
CCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHEECCCCHHEEEECC
QTCAVIVEPIQGEGGVLPADLEFLKGLRRLCDETGAVLIFDEVQTGVGRTGALYAYMNTG
CCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCEEEEEECCC
VVPDILTTAKALGGGFPIGAMITTDQYANVFVVGDHGTTYGGNPLACAVAGAVFNFINTA
CCHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
DVLDGVKQRSQQFIDELEQLNHTYAVFQEIRGQGLLLGCVLRPEYAGKAKDIVTLAGAEG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCC
LLALIAGPNVVRFTPSLVISEQEISEGLQRFGRALSQFVAVHQ
EEEEEECCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIHHLNRQDFNQFMVPVFAPAQFIPVRGQGSRLWDQDDKEYIDFAGGIAVNALGHAHPI
CCCCCCHHHHHHHHHHEECCCEEEEECCCCCCCCCCCCHHHHHHCCCEEEECCCCCCHH
AVNALIEQGQKLWHIGNGYTNEPVLALAKQLVDHTFADKVFFCNSGAEANEAALKLARKI
HHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHH
GLSKNKSKIVAFNNAFHGRTLFTVTAGGQPKYSQDFAPLPAGIEHVAFNDLNAAAAVIDD
CCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHEECCCCHHEEEECC
QTCAVIVEPIQGEGGVLPADLEFLKGLRRLCDETGAVLIFDEVQTGVGRTGALYAYMNTG
CCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECHHCCCCCCCEEEEEECCC
VVPDILTTAKALGGGFPIGAMITTDQYANVFVVGDHGTTYGGNPLACAVAGAVFNFINTA
CCHHHHHHHHHHCCCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
DVLDGVKQRSQQFIDELEQLNHTYAVFQEIRGQGLLLGCVLRPEYAGKAKDIVTLAGAEG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEEEEECCCC
LLALIAGPNVVRFTPSLVISEQEISEGLQRFGRALSQFVAVHQ
EEEEEECCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA