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The map label for this gene is gap [H]

Identifier: 50084441

GI number: 50084441

Start: 1254293

End: 1255315

Strand: Direct

Name: gap [H]

Synonym: ACIAD1255

Alternate gene names: 50084441

Gene position: 1254293-1255315 (Clockwise)

Preceding gene: 50084440

Following gene: 50084442

Centisome position: 34.85

GC content: 42.03

Gene sequence:

>1023_bases
ATGCAACGTATCGCCATTAATGGTTTTGGTCGGATTGGTCGGAATGTTTTACGTGCATGGTTTGAAAGCCCGAAATCATT
TAACTTTGATATCGTCGCGATCAATGATATTGCGGATGTAAAAACACTGGTTCATCTTTTTAAATACGACACTACGCATG
GCCCATTTCATGGGGAAGTTCAGGTTGAGTTGGAAAATGAACAAGTTATCTTGCATATTAAAGCAAATAATCGCGTACTC
AAGGTTCAGGTATATCGTGAAGAAGCGCCAGAAAACCTGCCTTGGCGTGCGCTTGAAATTGATGTCGTACTTGAATGTAC
TGGATTATTCCGATCACATTCAGATGCGATTCGACATCTGGGGGCAGGGGCAAATCGTGTGATTATCGGCGCTGCACCTT
TTGATAAGGTAGATGCAGCGATTGTGTATGGTGTTAATCATGCCGATGTAAAACCGACTGATCGGATTATTTCCAGCGTG
TCATGTACCACACAGGCACTCGTTCCTTTGGTCAAAATTATTGATGATGCATTTGGAATTGAAACAGCATTGATGACTGA
GATTCATGCCGTGACTGCAGACCAGTCTGTGCTAGATCATGCACATCGTGATTTACGTCGTGCACGAGCATCTGGTCAAA
ATATTATTCCGACCACATCAAGTGCACTAGGCGCATTAAAACGGGTCTTGCCAAAAATGGAAAATCGTATAGAAGGTTAT
TCTATTCGGGTTCCAACCATTAATGTTGCTGCAATTGATTTAACTTTTGTGGCGCAATCTGCAATGACGATACATCGTCT
CAATGAAGTACTCGTTCAAGCCGCACGACTGGATTATAGTGAAATTATGTCAGTCACAGATGAGCCGCTGGTTTCTAGTG
ATTTTAATCATTCACCCTATTCATTGATTGTCGATTTAACACAAACATTGGTTGTGGGACACCAAGCAAAAGTCTTTGCT
TGGTATGATAATGAGTGGGGATATGCAAATCGGTTGCTGGACTTGTGTGAGTCGTTTGAATAA

Upstream 100 bases:

>100_bases
GAAAGATCCATGACCAGAGTTGAGGTGTGGTTTACTCTATCTTCGATAGAATCAATCCTTTACCATAGTGATTTTATTTT
GGGTACATGAAGGATTCACC

Downstream 100 bases:

>100_bases
ATATTTTTCTAAATTTTAGAATATGATAGCGAAATGAGAGTAATTAATTTGATGTTTCAGTCAAGATATCTGATAAATCA
TAAAATTCTCAGGTGCATGG

Product: glyceraldehyde 3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MQRIAINGFGRIGRNVLRAWFESPKSFNFDIVAINDIADVKTLVHLFKYDTTHGPFHGEVQVELENEQVILHIKANNRVL
KVQVYREEAPENLPWRALEIDVVLECTGLFRSHSDAIRHLGAGANRVIIGAAPFDKVDAAIVYGVNHADVKPTDRIISSV
SCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVLPKMENRIEGY
SIRVPTINVAAIDLTFVAQSAMTIHRLNEVLVQAARLDYSEIMSVTDEPLVSSDFNHSPYSLIVDLTQTLVVGHQAKVFA
WYDNEWGYANRLLDLCESFE

Sequences:

>Translated_340_residues
MQRIAINGFGRIGRNVLRAWFESPKSFNFDIVAINDIADVKTLVHLFKYDTTHGPFHGEVQVELENEQVILHIKANNRVL
KVQVYREEAPENLPWRALEIDVVLECTGLFRSHSDAIRHLGAGANRVIIGAAPFDKVDAAIVYGVNHADVKPTDRIISSV
SCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVLPKMENRIEGY
SIRVPTINVAAIDLTFVAQSAMTIHRLNEVLVQAARLDYSEIMSVTDEPLVSSDFNHSPYSLIVDLTQTLVVGHQAKVFA
WYDNEWGYANRLLDLCESFE
>Mature_340_residues
MQRIAINGFGRIGRNVLRAWFESPKSFNFDIVAINDIADVKTLVHLFKYDTTHGPFHGEVQVELENEQVILHIKANNRVL
KVQVYREEAPENLPWRALEIDVVLECTGLFRSHSDAIRHLGAGANRVIIGAAPFDKVDAAIVYGVNHADVKPTDRIISSV
SCTTQALVPLVKIIDDAFGIETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVLPKMENRIEGY
SIRVPTINVAAIDLTFVAQSAMTIHRLNEVLVQAARLDYSEIMSVTDEPLVSSDFNHSPYSLIVDLTQTLVVGHQAKVFA
WYDNEWGYANRLLDLCESFE

Specific function: Could Play A Role In Pyridoxal 5'-Phosphate Synthesis. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=39.8809523809524, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI7657116, Length=336, Percent_Identity=37.797619047619, Blast_Score=220, Evalue=2e-57,
Organism=Escherichia coli, GI1789295, Length=333, Percent_Identity=44.7447447447448, Blast_Score=300, Evalue=1e-82,
Organism=Escherichia coli, GI1788079, Length=335, Percent_Identity=38.5074626865672, Blast_Score=236, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17534679, Length=336, Percent_Identity=38.6904761904762, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17534677, Length=336, Percent_Identity=38.3928571428571, Blast_Score=227, Evalue=6e-60,
Organism=Caenorhabditis elegans, GI17568413, Length=336, Percent_Identity=39.5833333333333, Blast_Score=225, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI32566163, Length=336, Percent_Identity=39.5833333333333, Blast_Score=225, Evalue=2e-59,
Organism=Saccharomyces cerevisiae, GI6322409, Length=340, Percent_Identity=37.9411764705882, Blast_Score=241, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6321631, Length=344, Percent_Identity=37.7906976744186, Blast_Score=240, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6322468, Length=344, Percent_Identity=37.7906976744186, Blast_Score=236, Evalue=5e-63,
Organism=Drosophila melanogaster, GI85725000, Length=347, Percent_Identity=37.463976945245, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI22023983, Length=347, Percent_Identity=37.463976945245, Blast_Score=224, Evalue=9e-59,
Organism=Drosophila melanogaster, GI17933600, Length=347, Percent_Identity=37.1757925072046, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI18110149, Length=347, Percent_Identity=37.1757925072046, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI19922412, Length=338, Percent_Identity=35.7988165680473, Blast_Score=208, Evalue=5e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37874; Mature: 37874

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIAINGFGRIGRNVLRAWFESPKSFNFDIVAINDIADVKTLVHLFKYDTTHGPFHGEV
CCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEE
QVELENEQVILHIKANNRVLKVQVYREEAPENLPWRALEIDVVLECTGLFRSHSDAIRHL
EEEEECCEEEEEEECCCEEEEEEEEECCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHH
GAGANRVIIGAAPFDKVDAAIVYGVNHADVKPTDRIISSVSCTTQALVPLVKIIDDAFGI
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH
ETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVLPKMENRIEGY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCE
SIRVPTINVAAIDLTFVAQSAMTIHRLNEVLVQAARLDYSEIMSVTDEPLVSSDFNHSPY
EEECCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCH
SLIVDLTQTLVVGHQAKVFAWYDNEWGYANRLLDLCESFE
HHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MQRIAINGFGRIGRNVLRAWFESPKSFNFDIVAINDIADVKTLVHLFKYDTTHGPFHGEV
CCEEEECCCHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCCCCCEE
QVELENEQVILHIKANNRVLKVQVYREEAPENLPWRALEIDVVLECTGLFRSHSDAIRHL
EEEEECCEEEEEEECCCEEEEEEEEECCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHH
GAGANRVIIGAAPFDKVDAAIVYGVNHADVKPTDRIISSVSCTTQALVPLVKIIDDAFGI
CCCCCEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH
ETALMTEIHAVTADQSVLDHAHRDLRRARASGQNIIPTTSSALGALKRVLPKMENRIEGY
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCE
SIRVPTINVAAIDLTFVAQSAMTIHRLNEVLVQAARLDYSEIMSVTDEPLVSSDFNHSPY
EEECCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCH
SLIVDLTQTLVVGHQAKVFAWYDNEWGYANRLLDLCESFE
HHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7763137 [H]