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The map label for this gene is mdmC [H]

Identifier: 50084423

GI number: 50084423

Start: 1236073

End: 1236660

Strand: Reverse

Name: mdmC [H]

Synonym: ACIAD1236

Alternate gene names: 50084423

Gene position: 1236660-1236073 (Counterclockwise)

Preceding gene: 50084424

Following gene: 50084421

Centisome position: 34.36

GC content: 37.76

Gene sequence:

>588_bases
ATGCCAAAATTACCTTTTATACAACGTGTTTCTGATTTATATGATCAGTTTCAAAAACATGATGCAAAGCAGACAGATCG
TTTACTGCGTTATCGCAATATTGAACCCGATTCGGCTCAATTTTTATCTATGTTGATTCGAATACAACACTCAAAAAATA
TTCTTGAAATTGGAACGTCTACAGGTCATTCCACACTGTGGCTAGCAGAAGCTGCACAACAAACTCAAGGAAAAGTAACT
ACACTTGAAATAGAGCCTGCACGAAGCCAACAGGCTGCAATGTTTGCACAAGAACTCGGCGTAAATCAATACGTTGATTT
TTGGATAGGTGATGCAGCAGATTATTTAAGTGAGTCCATTGAAGTTTTTGATTTGATTCTTCTTGATGCCGAGAGAAGCT
TTTATTCAGGTTACTGGGAAGATTTAAAGCGTTTGATAAAACCACATGGTGGTATATTAATTGTTGATAACGTCATTTCT
CATGCGACAGAAGTGAAGCCATTTCTTGAAATCATTCGTCATGACTCACGATTTATGAGTACAACCATCGCACTGGGTGC
GGGACTATTTATGGTCGTTTCACAATAA

Upstream 100 bases:

>100_bases
CGTAGAAGTGGACCAGCATATTATTCCACGTTTCCAATTTCTCCACCCAGTAGAATAATAATAATCTTTTAAATAATGAA
TAACTTATGAGAATTTGAAA

Downstream 100 bases:

>100_bases
GTAGAAATTTTATAAAATTGAAACCCTGTTAAAGTGCAAATCAAATTCGATATATTTATGAACAAAAGCGGCCTTATCGT
GTGCCCTTAATAAATTGTCA

Product: O-methyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MPKLPFIQRVSDLYDQFQKHDAKQTDRLLRYRNIEPDSAQFLSMLIRIQHSKNILEIGTSTGHSTLWLAEAAQQTQGKVT
TLEIEPARSQQAAMFAQELGVNQYVDFWIGDAADYLSESIEVFDLILLDAERSFYSGYWEDLKRLIKPHGGILIVDNVIS
HATEVKPFLEIIRHDSRFMSTTIALGAGLFMVVSQ

Sequences:

>Translated_195_residues
MPKLPFIQRVSDLYDQFQKHDAKQTDRLLRYRNIEPDSAQFLSMLIRIQHSKNILEIGTSTGHSTLWLAEAAQQTQGKVT
TLEIEPARSQQAAMFAQELGVNQYVDFWIGDAADYLSESIEVFDLILLDAERSFYSGYWEDLKRLIKPHGGILIVDNVIS
HATEVKPFLEIIRHDSRFMSTTIALGAGLFMVVSQ
>Mature_194_residues
PKLPFIQRVSDLYDQFQKHDAKQTDRLLRYRNIEPDSAQFLSMLIRIQHSKNILEIGTSTGHSTLWLAEAAQQTQGKVTT
LEIEPARSQQAAMFAQELGVNQYVDFWIGDAADYLSESIEVFDLILLDAERSFYSGYWEDLKRLIKPHGGILIVDNVISH
ATEVKPFLEIIRHDSRFMSTTIALGAGLFMVVSQ

Specific function: 4-O-methyltransferase for the lactone ring of midecamycin and other macrolide antibiotics [H]

COG id: COG4122

COG function: function code R; Predicted O-methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. Type 3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002935 [H]

Pfam domain/function: PF01596 Methyltransf_3 [H]

EC number: NA

Molecular weight: Translated: 22218; Mature: 22086

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLPFIQRVSDLYDQFQKHDAKQTDRLLRYRNIEPDSAQFLSMLIRIQHSKNILEIGTS
CCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCC
TGHSTLWLAEAAQQTQGKVTTLEIEPARSQQAAMFAQELGVNQYVDFWIGDAADYLSESI
CCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
EVFDLILLDAERSFYSGYWEDLKRLIKPHGGILIVDNVISHATEVKPFLEIIRHDSRFMS
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHH
TTIALGAGLFMVVSQ
HHHHHHCCCEEEECC
>Mature Secondary Structure 
PKLPFIQRVSDLYDQFQKHDAKQTDRLLRYRNIEPDSAQFLSMLIRIQHSKNILEIGTS
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEECCC
TGHSTLWLAEAAQQTQGKVTTLEIEPARSQQAAMFAQELGVNQYVDFWIGDAADYLSESI
CCCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHH
EVFDLILLDAERSFYSGYWEDLKRLIKPHGGILIVDNVISHATEVKPFLEIIRHDSRFMS
HHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCHHHHH
TTIALGAGLFMVVSQ
HHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1629172 [H]