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The map label for this gene is surE

Identifier: 50084415

GI number: 50084415

Start: 1228919

End: 1229686

Strand: Direct

Name: surE

Synonym: ACIAD1227

Alternate gene names: 50084415

Gene position: 1228919-1229686 (Clockwise)

Preceding gene: 50084405

Following gene: 50084416

Centisome position: 34.15

GC content: 43.88

Gene sequence:

>768_bases
GTGAATATTTTAATTGCGAATGATGACGGTGTATTTGCACCCGGGATACAAGCACTTGCACACGCACTAAAACCATTAGG
TCGTGTCGTAATTGTGGCACCAGAAAGTGAAAGAAGTGGTTATTCAAGCGCATTAACACTTGATCGCCCTTTGCGCCCAA
TCCAAATCTCGGAAGATGTTTGGGCTGTAAATGGAACACCAGCAGATTGCGTCTATCTATCCATGAATGGATTGTTTGAC
TTTGAGTTTGATCTGGTGGTCAGCGGGATTAATAGTGGAGCTAATCTCGGAGATGATGTGCTTTATTCGGGGACGGTTGG
GGCCGCATTTGAAGGTCGCTTGATGAAACAGCCAGCTATTGCTGTATCGCTAGCAGGAAGTAATGTGCGTTCTTATGAGC
ATGCTCATGATTATGCAGTAGCAGCAAAATGGGTACATGATTTTATTCAGAAAGGCCTGCCCAATTTACCACCACGTCAT
ATTCTTAATATTAATATCCCAGATGTTGCAGCATTAAAAGGCGAGAGAGTGACTTATCAGGGATTACGTGCTCAATCCAA
GCCGATTACCAGTCATGTCGATCCGCGTGGTCGCCAGGTATACTGGATTGGTCTGGCTGGTGAAGCAGTGACAGACCCGA
AAAAAACGTCATCTCATATTCAGTCTGATTTTTTTGCAGTTGCAAATGGTTACGTGAGTATTACACCTATTCAGATGGAC
GCGACCAATTACGATATCTTGGAAGACTTACAAACATATATAGGCTAG

Upstream 100 bases:

>100_bases
TAATTGGTTGTTGTATGTATGATAAATCTTGATTGTGCTACCAAAGATAAAGATATAATCAGGCCCTCATTTTACTCTTA
GATGAATCGAGTCAACTGCT

Downstream 100 bases:

>100_bases
AGCTATAACTGTACGTCATTTAAGTGTTGTAACTTTGTGAAAAAAAGAATGAGAAACTCGTTTATTCATTCTTTTTTGGT
AATCTTAGTGCAAATATTTG

Product: survival protein (acid phosphatase)

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MNILIANDDGVFAPGIQALAHALKPLGRVVIVAPESERSGYSSALTLDRPLRPIQISEDVWAVNGTPADCVYLSMNGLFD
FEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGSNVRSYEHAHDYAVAAKWVHDFIQKGLPNLPPRH
ILNINIPDVAALKGERVTYQGLRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPKKTSSHIQSDFFAVANGYVSITPIQMD
ATNYDILEDLQTYIG

Sequences:

>Translated_255_residues
MNILIANDDGVFAPGIQALAHALKPLGRVVIVAPESERSGYSSALTLDRPLRPIQISEDVWAVNGTPADCVYLSMNGLFD
FEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGSNVRSYEHAHDYAVAAKWVHDFIQKGLPNLPPRH
ILNINIPDVAALKGERVTYQGLRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPKKTSSHIQSDFFAVANGYVSITPIQMD
ATNYDILEDLQTYIG
>Mature_255_residues
MNILIANDDGVFAPGIQALAHALKPLGRVVIVAPESERSGYSSALTLDRPLRPIQISEDVWAVNGTPADCVYLSMNGLFD
FEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAIAVSLAGSNVRSYEHAHDYAVAAKWVHDFIQKGLPNLPPRH
ILNINIPDVAALKGERVTYQGLRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPKKTSSHIQSDFFAVANGYVSITPIQMD
ATNYDILEDLQTYIG

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=263, Percent_Identity=46.3878326996198, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_ACIAD (Q6FCV6)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045925.1
- ProteinModelPortal:   Q6FCV6
- SMR:   Q6FCV6
- STRING:   Q6FCV6
- GeneID:   2879242
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1227
- NMPDR:   fig|62977.3.peg.246
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q6FCV6
- ProtClustDB:   CLSK707247
- BioCyc:   ASP62977:ACIAD1227-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27575; Mature: 27575

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILIANDDGVFAPGIQALAHALKPLGRVVIVAPESERSGYSSALTLDRPLRPIQISEDV
CEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCEEECCCE
WAVNGTPADCVYLSMNGLFDFEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAI
EEECCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCEECCCCE
AVSLAGSNVRSYEHAHDYAVAAKWVHDFIQKGLPNLPPRHILNINIPDVAALKGERVTYQ
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHCCCCEEEEC
GLRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPKKTSSHIQSDFFAVANGYVSITPIQMD
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEECCEEEEEEEEEC
ATNYDILEDLQTYIG
CCCHHHHHHHHHHCC
>Mature Secondary Structure
MNILIANDDGVFAPGIQALAHALKPLGRVVIVAPESERSGYSSALTLDRPLRPIQISEDV
CEEEEECCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCCCCCEEECCCE
WAVNGTPADCVYLSMNGLFDFEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAI
EEECCCCCCEEEEEECCCEEEEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCEECCCCE
AVSLAGSNVRSYEHAHDYAVAAKWVHDFIQKGLPNLPPRHILNINIPDVAALKGERVTYQ
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHCCCCEEEEC
GLRAQSKPITSHVDPRGRQVYWIGLAGEAVTDPKKTSSHIQSDFFAVANGYVSITPIQMD
CCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEECCEEEEEEEEEC
ATNYDILEDLQTYIG
CCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA