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The map label for this gene is sohB [H]

Identifier: 50084405

GI number: 50084405

Start: 1220297

End: 1221259

Strand: Direct

Name: sohB [H]

Synonym: ACIAD1216

Alternate gene names: 50084405

Gene position: 1220297-1221259 (Clockwise)

Preceding gene: 50084404

Following gene: 50084415

Centisome position: 33.91

GC content: 40.6

Gene sequence:

>963_bases
ATGTTATTTCATTTACCCAAACTTCCTGCCGAATTACGTGTAAGTCATTTAAATGCGCGTGTAAATGAACAACGAAAAAA
GATCGCACAAACAACAGCATCTAAGCTCGAATTTTTACAATTAACTCAACAGCTTGTAAAAGAAGCGAAGATTCGCAAAA
AAAATAATCAGAAAATTTTTGTGCTTGATTTTAAGGGGGACATTCAAGCCTCTGCTGTAGACCAGTTGCGTGAAGAAATC
ACATTAATCCTTGCCACAGCAAAATCTGGTAAAGATCGCGTGGTGTTGCGTCTTGAAAGCCCTGGCGGAATGGTACATGG
TTATGGTCTAGCTGCTGCACAGCTTGTGCGATTACGTGATGCTGGTTTTCATTTGACCATTGTAGTCGATAAAGTCGCTG
CCAGTGGTGGTTACATGATGGCTTGTATCGCTAATGAAATCGTGTCAGCCCCATTTGCAATTTTAGGTTCAATTGGTGTG
GTTGCTCAAGTTCCAAATTTCAATCGTTTGCTTAAAGAGCATAATGTTGATTTCGAATTGTATACGGCAGGAGAGTACAA
ACGTACTGTAACCATGTTTGGTGAAAATACACCAGAAGGTAAAGCCAAGTTTGAAGAAGAGTTAAAGCAAACACATGCAT
TGTTTAAACATTTTGTTGAAAAGTATCGCCCTCAGTTAAATGTAGAAAAAGTTGCGACGGGTGAGCATTGGTACGGGCAG
GATGCATTGGATCTGAATCTGGTCGATAAGTTGCAAACGTCGGACGAATATTTGCTAAGTCTGCTTCCTCAACATGACGT
GTATGTGATTACAACGCGTAAAAAGCCAACGCTTGGCGAAAGATTAGGGCTTCAAGCTGCTCAGCTTGCAGATAGCTTTA
TTCCAGCAGTCATGAATAAAGTGGTTGAAAGTCTGGTGAACGCAAATAGTCATTTGGTTCAGATGCGCGATCCTAAAATT
TAA

Upstream 100 bases:

>100_bases
CCAAGATCATGATCACATCATTTTCAAAATAGATATTGAATTCTGGATTAAATGACCTCATCTTAGTTTAAATACAGCGA
AATTAGAGAATAGCCAAACT

Downstream 100 bases:

>100_bases
TTTTTCTCATCTAAATACTAAAGCACTCGATTAAGAGTGCTTTTTATTGCCTAGTAATTGCAACAAACCGAACATAAGAG
TGCCAATCGTCGCCATAAGC

Product: periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MLFHLPKLPAELRVSHLNARVNEQRKKIAQTTASKLEFLQLTQQLVKEAKIRKKNNQKIFVLDFKGDIQASAVDQLREEI
TLILATAKSGKDRVVLRLESPGGMVHGYGLAAAQLVRLRDAGFHLTIVVDKVAASGGYMMACIANEIVSAPFAILGSIGV
VAQVPNFNRLLKEHNVDFELYTAGEYKRTVTMFGENTPEGKAKFEEELKQTHALFKHFVEKYRPQLNVEKVATGEHWYGQ
DALDLNLVDKLQTSDEYLLSLLPQHDVYVITTRKKPTLGERLGLQAAQLADSFIPAVMNKVVESLVNANSHLVQMRDPKI

Sequences:

>Translated_320_residues
MLFHLPKLPAELRVSHLNARVNEQRKKIAQTTASKLEFLQLTQQLVKEAKIRKKNNQKIFVLDFKGDIQASAVDQLREEI
TLILATAKSGKDRVVLRLESPGGMVHGYGLAAAQLVRLRDAGFHLTIVVDKVAASGGYMMACIANEIVSAPFAILGSIGV
VAQVPNFNRLLKEHNVDFELYTAGEYKRTVTMFGENTPEGKAKFEEELKQTHALFKHFVEKYRPQLNVEKVATGEHWYGQ
DALDLNLVDKLQTSDEYLLSLLPQHDVYVITTRKKPTLGERLGLQAAQLADSFIPAVMNKVVESLVNANSHLVQMRDPKI
>Mature_320_residues
MLFHLPKLPAELRVSHLNARVNEQRKKIAQTTASKLEFLQLTQQLVKEAKIRKKNNQKIFVLDFKGDIQASAVDQLREEI
TLILATAKSGKDRVVLRLESPGGMVHGYGLAAAQLVRLRDAGFHLTIVVDKVAASGGYMMACIANEIVSAPFAILGSIGV
VAQVPNFNRLLKEHNVDFELYTAGEYKRTVTMFGENTPEGKAKFEEELKQTHALFKHFVEKYRPQLNVEKVATGEHWYGQ
DALDLNLVDKLQTSDEYLLSLLPQHDVYVITTRKKPTLGERLGLQAAQLADSFIPAVMNKVVESLVNANSHLVQMRDPKI

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=237, Percent_Identity=60.7594936708861, Blast_Score=303, Evalue=8e-84,
Organism=Escherichia coli, GI1788064, Length=243, Percent_Identity=27.1604938271605, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 35810; Mature: 35810

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFHLPKLPAELRVSHLNARVNEQRKKIAQTTASKLEFLQLTQQLVKEAKIRKKNNQKIF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VLDFKGDIQASAVDQLREEITLILATAKSGKDRVVLRLESPGGMVHGYGLAAAQLVRLRD
EEEECCCCCHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHC
AGFHLTIVVDKVAASGGYMMACIANEIVSAPFAILGSIGVVAQVPNFNRLLKEHNVDFEL
CCEEEEEEEEEECCCCCEEHHHHHHHHHHCCHHHHHCCCCEEECCCHHHHHHHCCCCEEE
YTAGEYKRTVTMFGENTPEGKAKFEEELKQTHALFKHFVEKYRPQLNVEKVATGEHWYGQ
EECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCCC
DALDLNLVDKLQTSDEYLLSLLPQHDVYVITTRKKPTLGERLGLQAAQLADSFIPAVMNK
CCCCHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHH
VVESLVNANSHLVQMRDPKI
HHHHHHCCCCEEEEECCCCC
>Mature Secondary Structure
MLFHLPKLPAELRVSHLNARVNEQRKKIAQTTASKLEFLQLTQQLVKEAKIRKKNNQKIF
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VLDFKGDIQASAVDQLREEITLILATAKSGKDRVVLRLESPGGMVHGYGLAAAQLVRLRD
EEEECCCCCHHHHHHHHHHHEEEEEECCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHC
AGFHLTIVVDKVAASGGYMMACIANEIVSAPFAILGSIGVVAQVPNFNRLLKEHNVDFEL
CCEEEEEEEEEECCCCCEEHHHHHHHHHHCCHHHHHCCCCEEECCCHHHHHHHCCCCEEE
YTAGEYKRTVTMFGENTPEGKAKFEEELKQTHALFKHFVEKYRPQLNVEKVATGEHWYGQ
EECCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEECCCCCCCC
DALDLNLVDKLQTSDEYLLSLLPQHDVYVITTRKKPTLGERLGLQAAQLADSFIPAVMNK
CCCCHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHH
VVESLVNANSHLVQMRDPKI
HHHHHHCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]