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The map label for this gene is hchA [H]

Identifier: 50084355

GI number: 50084355

Start: 1162236

End: 1163105

Strand: Direct

Name: hchA [H]

Synonym: ACIAD1164

Alternate gene names: 50084355

Gene position: 1162236-1163105 (Clockwise)

Preceding gene: 50084354

Following gene: 50084356

Centisome position: 32.3

GC content: 36.09

Gene sequence:

>870_bases
ATGAGTGAATTAAGTAAAACACCTACTCCAGACCAAGCTGAAGATAATGCTTTTTTCCCATCACCTTATTCATTAAGCCA
ATATACTTCTTCTAAAACGGACTATGACGGAAGCACATACGACAAACCCTATCAAGGCGATAAAAAAATTCTGATGATTG
CAACGGATGAACGTTACATTCTGATGCAAAATGAAAAATTTTTCTCTACAGGAAACCATCCAGTCGAAATGTTACTTCCA
ATGTTTCATCTAGACAATGCTGGTTTTAAATTTGATGTTGCAACTTTATCTGGTAACCCTGTCAAACTCGAAATGTGGGC
TATGCCAAGTGAAGAAAAAGTTGTATTAGATACTTATAACAAATATCTTGAACAGTTGAAGCAACCGTTAAAACTTGCAG
ATATTCTTAAAGAAGCCATTGGTGAAAACTCTCCATATGCGGGTGTGTTTATTCCTGGTGGGCATGGCGTATTAGCAAAA
ATCCCTGAGAGTTCAGAAGTAAAACAAGTTCTGAAATGGGCAATGGATCATAATAAATATGTAATTACATTGTGTCATGG
GCCTGCTTCTCTACTTGCAGCGGCTGTTGATGAATCATCAGAAAACTACATCTTCAAGGGTTATGAAATTTGTGTATTCC
CAGATTCATTAGATAAGGGTGCAAATATTGATATTGGTTATATGCCTGGTAAATTGCAGTGGTTAGTTGGTGAAAATCTG
GAGAAATTAGGTGTCAAAGTTTTAAATAAAGGCATTACGGGTCAAGTTCATAAAGATCGAAAATTGTTGACTGGTGATAG
TCCTTTGGCATCAAATAATTTAGGTAAATTGGCTGCAGAAACATTATTGGCAGATCCTGAATTTGCATAA

Upstream 100 bases:

>100_bases
GTACAAGTAAGGGATTTCCCTTATATAAATGCTTTGGTGAAGCTGACTATACTGTGGCTACCTATCAATTCCTTGATAAA
TGTTATTATGGAGCATAACC

Downstream 100 bases:

>100_bases
TCCATGATATCTTTAGAAAAATAGTCTCAGAACGAGGCTATTTTTTATTAAAAATTGATTTTTAAAAATTTTCATCAATT
ATATAGGTGGCATTATGTAT

Product: chaperone protein HchA

Products: NA

Alternate protein names: Hsp31 [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MSELSKTPTPDQAEDNAFFPSPYSLSQYTSSKTDYDGSTYDKPYQGDKKILMIATDERYILMQNEKFFSTGNHPVEMLLP
MFHLDNAGFKFDVATLSGNPVKLEMWAMPSEEKVVLDTYNKYLEQLKQPLKLADILKEAIGENSPYAGVFIPGGHGVLAK
IPESSEVKQVLKWAMDHNKYVITLCHGPASLLAAAVDESSENYIFKGYEICVFPDSLDKGANIDIGYMPGKLQWLVGENL
EKLGVKVLNKGITGQVHKDRKLLTGDSPLASNNLGKLAAETLLADPEFA

Sequences:

>Translated_289_residues
MSELSKTPTPDQAEDNAFFPSPYSLSQYTSSKTDYDGSTYDKPYQGDKKILMIATDERYILMQNEKFFSTGNHPVEMLLP
MFHLDNAGFKFDVATLSGNPVKLEMWAMPSEEKVVLDTYNKYLEQLKQPLKLADILKEAIGENSPYAGVFIPGGHGVLAK
IPESSEVKQVLKWAMDHNKYVITLCHGPASLLAAAVDESSENYIFKGYEICVFPDSLDKGANIDIGYMPGKLQWLVGENL
EKLGVKVLNKGITGQVHKDRKLLTGDSPLASNNLGKLAAETLLADPEFA
>Mature_288_residues
SELSKTPTPDQAEDNAFFPSPYSLSQYTSSKTDYDGSTYDKPYQGDKKILMIATDERYILMQNEKFFSTGNHPVEMLLPM
FHLDNAGFKFDVATLSGNPVKLEMWAMPSEEKVVLDTYNKYLEQLKQPLKLADILKEAIGENSPYAGVFIPGGHGVLAKI
PESSEVKQVLKWAMDHNKYVITLCHGPASLLAAAVDESSENYIFKGYEICVFPDSLDKGANIDIGYMPGKLQWLVGENLE
KLGVKVLNKGITGQVHKDRKLLTGDSPLASNNLGKLAAETLLADPEFA

Specific function: Uses temperature-induced exposure of structured hydrophobic domains to capture and stabilize early unfolding protein intermediates under severe thermal stress. It rapidly releases them once stress has abated [H]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C56 family. HchA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788278, Length=282, Percent_Identity=53.5460992907801, Blast_Score=311, Evalue=3e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017283
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 31978; Mature: 31847

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELSKTPTPDQAEDNAFFPSPYSLSQYTSSKTDYDGSTYDKPYQGDKKILMIATDERYI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEE
LMQNEKFFSTGNHPVEMLLPMFHLDNAGFKFDVATLSGNPVKLEMWAMPSEEKVVLDTYN
EEECCEEECCCCCCHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEECCCCCEEEHHHHH
KYLEQLKQPLKLADILKEAIGENSPYAGVFIPGGHGVLAKIPESSEVKQVLKWAMDHNKY
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCE
VITLCHGPASLLAAAVDESSENYIFKGYEICVFPDSLDKGANIDIGYMPGKLQWLVGENL
EEEEECCHHHHHHHHHCCCCCCEEEECEEEEEECCCCCCCCCEEEEECCCEEEEEECCCH
EKLGVKVLNKGITGQVHKDRKLLTGDSPLASNNLGKLAAETLLADPEFA
HHHHHHHHCCCCCCCEECCCEEECCCCCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SELSKTPTPDQAEDNAFFPSPYSLSQYTSSKTDYDGSTYDKPYQGDKKILMIATDERYI
CCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCEEE
LMQNEKFFSTGNHPVEMLLPMFHLDNAGFKFDVATLSGNPVKLEMWAMPSEEKVVLDTYN
EEECCEEECCCCCCHHHHHHHHEECCCCCEEEEEEECCCCEEEEEEECCCCCEEEHHHHH
KYLEQLKQPLKLADILKEAIGENSPYAGVFIPGGHGVLAKIPESSEVKQVLKWAMDHNKY
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHHCCCCE
VITLCHGPASLLAAAVDESSENYIFKGYEICVFPDSLDKGANIDIGYMPGKLQWLVGENL
EEEEECCHHHHHHHHHCCCCCCEEEECEEEEEECCCCCCCCCEEEEECCCEEEEEECCCH
EKLGVKVLNKGITGQVHKDRKLLTGDSPLASNNLGKLAAETLLADPEFA
HHHHHHHHCCCCCCCEECCCEEECCCCCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA