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The map label for this gene is nahR [H]

Identifier: 50084280

GI number: 50084280

Start: 1078291

End: 1079280

Strand: Reverse

Name: nahR [H]

Synonym: ACIAD1082

Alternate gene names: 50084280

Gene position: 1079280-1078291 (Counterclockwise)

Preceding gene: 50084283

Following gene: 50084279

Centisome position: 29.99

GC content: 40.61

Gene sequence:

>990_bases
ATGAATCTGGAGCGAGTCGACCTCAATCTATTAATTTATCTTGATGTACTACTTCGCGAAAAGAACGTTACTCGTGCAGC
TGAACAGCTAGGTGTGACACAACCCGCCATGAGTAATATCTTACGCCGTTTGCGTAATTTGTTTAATGATCCATTATTAA
TCCGTTCTTCTGAAGGTATGACGCCAACTGAACGTGCACTGGAATTACAACCACGTATTCGAGATGCCTTGTCAGACCTT
TCCATGATTCTTGAACCAAGAACAGAATTTAGACCTTATACCAGCAGTCGTGTATTTAGAATCATGACATCAGACTATGC
CGAGGCAACTCTCATTCCTCGTCTGATTAAAGCTTTACGTTCTGAAGCACCCAATGTAGTTTTAGATTTTTTAACACCAA
GTGATGTCTCTTACCGAGATATGGAACAAGGTAAAGTCGATTTGGCAATCAATCGCTTTAATGATATCCCTCAAAGCTTC
CATCAGGTGTTGGTATGGCGCGATAGCTTTAGCTGCTTACTGAATGACAAACATCCAGCAGTACAACATCTTAATTTAAA
AAGTTATCTGGATGCACAACATATCTGGGTCTCTAAAACAGGTATGGGTGTGGGTTTTGGCGTTAATCCAGATAAACAGG
CTGGTTTAGGCTGGATTGATCAAGCGCTAGAGCGAATTGGTCAAAAACGCAAAATCTCTGTATTTACCCGTCACTATCAA
ATGCCTGCACTCTTAGCTCAGAATGTAGATTTAATTGCAACCTTGCCAACCCGTATCGCGCGCTTACAAGCGCAAAATCC
AAAACTGGTCATCAAAGACCCACCATTTTATATTCCAGAATTTGAACTAAAAATGGCATGGTGCCCACTTCTACATCATC
ATCCAGCGCATCGTTGGTTACGTCAATTGATTCTGTTTGTAGCACGTCAGATGATTGAAGAAGAAAATCGTGAATTTATG
GTCAATAATTCACAATTTTCTCACTACTAA

Upstream 100 bases:

>100_bases
CAATAAAGTTGTTTCTTTTTTGAGTTTACTTTCACACAAAGCAATTTAACTGTGGCATAATCCTAAACAATTTCTCAATT
TTATTCTCGGTATTTTTTTT

Downstream 100 bases:

>100_bases
ATCAAATTTTTCTTAAATTCTTCTTTTTTCAAGCTTATACTAATTTTATCTGGAGGTAGTCCTATCTGCCTCCCCGCTTT
CTATTTAAATTTTCGCACAA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNLERVDLNLLIYLDVLLREKNVTRAAEQLGVTQPAMSNILRRLRNLFNDPLLIRSSEGMTPTERALELQPRIRDALSDL
SMILEPRTEFRPYTSSRVFRIMTSDYAEATLIPRLIKALRSEAPNVVLDFLTPSDVSYRDMEQGKVDLAINRFNDIPQSF
HQVLVWRDSFSCLLNDKHPAVQHLNLKSYLDAQHIWVSKTGMGVGFGVNPDKQAGLGWIDQALERIGQKRKISVFTRHYQ
MPALLAQNVDLIATLPTRIARLQAQNPKLVIKDPPFYIPEFELKMAWCPLLHHHPAHRWLRQLILFVARQMIEEENREFM
VNNSQFSHY

Sequences:

>Translated_329_residues
MNLERVDLNLLIYLDVLLREKNVTRAAEQLGVTQPAMSNILRRLRNLFNDPLLIRSSEGMTPTERALELQPRIRDALSDL
SMILEPRTEFRPYTSSRVFRIMTSDYAEATLIPRLIKALRSEAPNVVLDFLTPSDVSYRDMEQGKVDLAINRFNDIPQSF
HQVLVWRDSFSCLLNDKHPAVQHLNLKSYLDAQHIWVSKTGMGVGFGVNPDKQAGLGWIDQALERIGQKRKISVFTRHYQ
MPALLAQNVDLIATLPTRIARLQAQNPKLVIKDPPFYIPEFELKMAWCPLLHHHPAHRWLRQLILFVARQMIEEENREFM
VNNSQFSHY
>Mature_329_residues
MNLERVDLNLLIYLDVLLREKNVTRAAEQLGVTQPAMSNILRRLRNLFNDPLLIRSSEGMTPTERALELQPRIRDALSDL
SMILEPRTEFRPYTSSRVFRIMTSDYAEATLIPRLIKALRSEAPNVVLDFLTPSDVSYRDMEQGKVDLAINRFNDIPQSF
HQVLVWRDSFSCLLNDKHPAVQHLNLKSYLDAQHIWVSKTGMGVGFGVNPDKQAGLGWIDQALERIGQKRKISVFTRHYQ
MPALLAQNVDLIATLPTRIARLQAQNPKLVIKDPPFYIPEFELKMAWCPLLHHHPAHRWLRQLILFVARQMIEEENREFM
VNNSQFSHY

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=312, Percent_Identity=25.3205128205128, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081766, Length=261, Percent_Identity=24.1379310344828, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1786820, Length=79, Percent_Identity=40.5063291139241, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38160; Mature: 38160

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50931 HTH_LYSR ; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLERVDLNLLIYLDVLLREKNVTRAAEQLGVTQPAMSNILRRLRNLFNDPLLIRSSEGM
CCCCEEEHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
TPTERALELQPRIRDALSDLSMILEPRTEFRPYTSSRVFRIMTSDYAEATLIPRLIKALR
CHHHHHHHCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHH
SEAPNVVLDFLTPSDVSYRDMEQGKVDLAINRFNDIPQSFHQVLVWRDSFSCLLNDKHPA
CCCCCEEEEECCCCCCCHHHHHCCCEEEEEHHHHCCHHHHHHHHHCCCCHHEEECCCCCH
VQHLNLKSYLDAQHIWVSKTGMGVGFGVNPDKQAGLGWIDQALERIGQKRKISVFTRHYQ
HHHCCHHHHHCHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHH
MPALLAQNVDLIATLPTRIARLQAQNPKLVIKDPPFYIPEFELKMAWCPLLHHHPAHRWL
HHHHHHCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHH
RQLILFVARQMIEEENREFMVNNSQFSHY
HHHHHHHHHHHHHHCCCEEEEECCCCCCC
>Mature Secondary Structure
MNLERVDLNLLIYLDVLLREKNVTRAAEQLGVTQPAMSNILRRLRNLFNDPLLIRSSEGM
CCCCEEEHHHHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCC
TPTERALELQPRIRDALSDLSMILEPRTEFRPYTSSRVFRIMTSDYAEATLIPRLIKALR
CHHHHHHHCCHHHHHHHHHHHHHHCCCHHCCCCCCCCEEEEHHHCHHHHHHHHHHHHHHH
SEAPNVVLDFLTPSDVSYRDMEQGKVDLAINRFNDIPQSFHQVLVWRDSFSCLLNDKHPA
CCCCCEEEEECCCCCCCHHHHHCCCEEEEEHHHHCCHHHHHHHHHCCCCHHEEECCCCCH
VQHLNLKSYLDAQHIWVSKTGMGVGFGVNPDKQAGLGWIDQALERIGQKRKISVFTRHYQ
HHHCCHHHHHCHHHEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEHHHHHHHH
MPALLAQNVDLIATLPTRIARLQAQNPKLVIKDPPFYIPEFELKMAWCPLLHHHPAHRWL
HHHHHHCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCHHHHHH
RQLILFVARQMIEEENREFMVNNSQFSHY
HHHHHHHHHHHHHHCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]