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The map label for this gene is mtgA

Identifier: 50084261

GI number: 50084261

Start: 1056689

End: 1057363

Strand: Direct

Name: mtgA

Synonym: ACIAD1061

Alternate gene names: 50084261

Gene position: 1056689-1057363 (Clockwise)

Preceding gene: 50084259

Following gene: 50084262

Centisome position: 29.36

GC content: 38.52

Gene sequence:

>675_bases
ATGAAAAGATTTATTGTTCGCGCAGTGTTAATTCTTGTCAGTTTTGTGCTGTTAATACAATTATGGATTTTTTGTAGTCT
GGCGTGGTGGAGAACACACCCTGTAGAAACGACCATGTTTATGCGTTTAGATTACTGGTCTGACTCTTCTAAACCCATTC
AACAGCAATGGCGAGATTATGACGAAATTAGTGATAATTTTAAAAAGGCTGTGGTGGCAGCCGAAGATGGCAAATTTGTT
CATCATCATGGTTTTGACTGGGAAGGAATTCAATACGCTTTAGAAAAGAATGAAAAGTCAGGTGAAGTCGTAAATGGTGG
ATCTACAATTTCCCAGCAGCTTGCCAAAAACTTGTTTTTATATAATCAACGATCATTGATTCGAAAGGGACAAGAAGCGA
TAGCCACTTGGATGATGGAGCGCATGTGGTCTAAGCAGCGTATTTTGGAAGTTTATATGAACTCTGTTCAATTTGGTGAT
CATCTCTATGGGGTAGAAGCAGCTTCACATTACTATTTTCATCGGAGCGCGCAAAACTTAACACGTGATCAGGCTGCATT
TCTGGCTGCACTTTTACCCAATCCAAAATATTATCAAGAAAACCGTAATGATCCACGCTTTAAATTTAAGAAGCGCTTTA
CTCTAAAATATATGCGTTATAGTGAGATTCCGTAA

Upstream 100 bases:

>100_bases
CGGAGGTGTAAGTTCAGACATGCTATGCTTTTGTTATACATGGATAAGATTTCGATTAGCTTAGCATGAATTATCAATAT
TTCTGGAGAAACAAACTGGC

Downstream 100 bases:

>100_bases
AAAGATAAACTTTGGATAAAAAACATAAAAAAACACGTTTAAGGGGTGTTTTTTTATGTAATTGAAATAATTTTGAAGCA
TACTAATTACAGAATTTTGC

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKRFIVRAVLILVSFVLLIQLWIFCSLAWWRTHPVETTMFMRLDYWSDSSKPIQQQWRDYDEISDNFKKAVVAAEDGKFV
HHHGFDWEGIQYALEKNEKSGEVVNGGSTISQQLAKNLFLYNQRSLIRKGQEAIATWMMERMWSKQRILEVYMNSVQFGD
HLYGVEAASHYYFHRSAQNLTRDQAAFLAALLPNPKYYQENRNDPRFKFKKRFTLKYMRYSEIP

Sequences:

>Translated_224_residues
MKRFIVRAVLILVSFVLLIQLWIFCSLAWWRTHPVETTMFMRLDYWSDSSKPIQQQWRDYDEISDNFKKAVVAAEDGKFV
HHHGFDWEGIQYALEKNEKSGEVVNGGSTISQQLAKNLFLYNQRSLIRKGQEAIATWMMERMWSKQRILEVYMNSVQFGD
HLYGVEAASHYYFHRSAQNLTRDQAAFLAALLPNPKYYQENRNDPRFKFKKRFTLKYMRYSEIP
>Mature_224_residues
MKRFIVRAVLILVSFVLLIQLWIFCSLAWWRTHPVETTMFMRLDYWSDSSKPIQQQWRDYDEISDNFKKAVVAAEDGKFV
HHHGFDWEGIQYALEKNEKSGEVVNGGSTISQQLAKNLFLYNQRSLIRKGQEAIATWMMERMWSKQRILEVYMNSVQFGD
HLYGVEAASHYYFHRSAQNLTRDQAAFLAALLPNPKYYQENRNDPRFKFKKRFTLKYMRYSEIP

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=223, Percent_Identity=39.9103139013453, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI87082258, Length=138, Percent_Identity=39.1304347826087, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786343, Length=152, Percent_Identity=39.4736842105263, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788867, Length=165, Percent_Identity=29.6969696969697, Blast_Score=68, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_ACIAD (O24849)

Other databases:

- EMBL:   Z46863
- EMBL:   CR543861
- RefSeq:   YP_045771.1
- ProteinModelPortal:   O24849
- SMR:   O24849
- STRING:   O24849
- GeneID:   2879151
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD1061
- NMPDR:   fig|62977.3.peg.1156
- eggNOG:   COG0744
- HOGENOM:   HBG685698
- OMA:   RISIHLK
- PhylomeDB:   O24849
- ProtClustDB:   CLSK707184
- BioCyc:   ASP62977:ACIAD1061-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 26713; Mature: 26713

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1621f974)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRFIVRAVLILVSFVLLIQLWIFCSLAWWRTHPVETTMFMRLDYWSDSSKPIQQQWRDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHCCH
DEISDNFKKAVVAAEDGKFVHHHGFDWEGIQYALEKNEKSGEVVNGGSTISQQLAKNLFL
HHHHHHHHHHEEEECCCCEEECCCCCHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHH
YNQRSLIRKGQEAIATWMMERMWSKQRILEVYMNSVQFGDHLYGVEAASHYYFHRSAQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TRDQAAFLAALLPNPKYYQENRNDPRFKFKKRFTLKYMRYSEIP
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure
MKRFIVRAVLILVSFVLLIQLWIFCSLAWWRTHPVETTMFMRLDYWSDSSKPIQQQWRDY
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHCCH
DEISDNFKKAVVAAEDGKFVHHHGFDWEGIQYALEKNEKSGEVVNGGSTISQQLAKNLFL
HHHHHHHHHHEEEECCCCEEECCCCCHHHHHHHHHCCCCCCCEECCCHHHHHHHHHHHHH
YNQRSLIRKGQEAIATWMMERMWSKQRILEVYMNSVQFGDHLYGVEAASHYYFHRSAQNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
TRDQAAFLAALLPNPKYYQENRNDPRFKFKKRFTLKYMRYSEIP
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7670642; 9074511