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The map label for this gene is pfeA [H]

Identifier: 50084253

GI number: 50084253

Start: 1045245

End: 1047422

Strand: Direct

Name: pfeA [H]

Synonym: ACIAD1053

Alternate gene names: 50084253

Gene position: 1045245-1047422 (Clockwise)

Preceding gene: 50084252

Following gene: 50084254

Centisome position: 29.05

GC content: 38.11

Gene sequence:

>2178_bases
ATGTATAAGCCGCTATTTCGTACAGTTTTATCAATAGCAATATTAAGTAGTATGTTTTCAGTCGCTTATGCAGAAGAAAC
TGAGCAAAAAGATACCCAAAAATTAGAAAAAATTATACTCACGGCGGAAGAACAGATTAAGCAATCCTTGGGAGTATCTG
TGATCACTGCTGAAGATTTAGAACGTATTCCAGTGGTCAATGATATTTCAGAATATTTGCGAAAAATGCCTGGCGTAAAT
TTAACTGGAAATAGTTCAACGGGACAACGTGGGAATAATCGTCAGATTGATATTCGAGGTATGGGACCAGAAAATACTTT
AATTTTAATTGATGGTAAACCTGTCACTTCACGTAACTCTGTACGTTATGGTTGGAGAGGAGAGCGAGATACTCGAGGCG
ATTCAAATTGGGTACCAGCCGATGCAATCGAATCTATTGAGGTAATTCGGGGGCCAGCCGCTGCACGTTATGGTAATGGT
GCAATGGGTGGAGTTGTAAATATAAAAACCAAGAAAGTTACCAATGAAGCTCATGGCACATTAGAGTTGTATACGAATCA
GCCTGAAAATAGTAAAGAAGGCGATACAAACCGTGTCAGTCTGAACTTAAGCGGTCCACTGATTAAAGATATCCTCTCTT
ACCGAATCTATGGCAATTTTAATAAAACAAAAAACGATGCCGTAGATATTAATCCTCTTATTCCAAGTTCAGGGTATCGG
GCCGCAGGACGTGAAGGCTTTGAAAATAAAGATCTAAATGCACGTTTTGCATGGCAGTCAACAGATAACCAAACGATCTT
GTTTGATTTAGGATCGAGTCGCCAAGGCAACTTATATGCGGGTGATTCTCAAAATAGTAATCTGGACCCTACTGCAAATG
CGATTTTATCGGAATTAATTGACAAGGAAACCAATACAATCTGGAAAGATAGTTACGCGATTACGCATGAAGGAAAATGG
CAATGGGGAGACAGCCGCGTTATTGCACAATTTGATCGAACTAAAAATAAACGTTTTGCCGAAGGTACAGCAGGTGCAGC
AGAAGGGCGAATCAATAATTTGGATAATCGTACAACTTCAACGCTTGATACTATTCGTTTAAATGGTGAAGTTAATATTC
CATTAGATATCTATGTGCCCCAGAATTTGACGCTAGGTACAGAATGGGTGGAGGATCACTTTAAAGATCCAGGTAATACA
ACTCAAGGTACAGGTTCATATGCAGATTCATTGACCAGTGGAGATCGTAGCAAAATGAACTCTCGCATCGCTTCTGCCTA
TATTGAAGATAACTTGAAAATCACAGATTCTACAGATTTTGTAATGGGTCTAAGATTCGATGATCATAGTAAATCAGGAT
CAAATTGGAGTCCCAGTTTAAATATTACGCAACGTTTAGGTGACTATTTCACTTTAAAAGGTGGAATTGCTAGAGCTTAT
AAGGCACCGAACCTTTATCAAAATGCTTCAGGCTATCTACTTGCAACCAATGGTAATGGTTGTCCAATTGGTTTAACTCA
ATGCGTATTACAGGGCAATGACAATTTAAAACCAGAGACATCAGTAAATAAAGAAATAGGGATTCAGTTTCAAAAAGACA
TCGTCAATGCAAGCTTAGCCTGGTTCCGTAATGATTATAAAGATAAAATCAGTTCTGGTAATGAAGTTACTCAGCAAGTA
ACAATTGGGGGCATCACATATAACGTTTTACAGTGGACCAATATTCCAAAGGCGCTCGTTCAAGGGGTAGAAGGAAATAT
TAGTCTGGATTGGGGTAATATTAGCTGGACGAATAATCTGACATATATGGTAGATTCTGTTGATAAACAGACTGGTAACC
CGCTGTCTGTTATTCCAAAATATACGATTAACTCGATTCTGAATTATCAAATTACGGATAAAACAGATGTGAACTTTGTC
TATACAATGTATGGCCGTCAAAAACCACGTCAATATGTAGAAACAAATCTAGAGAATAGCCGGGGTATTGCTACTCAAAG
CATCAGGAGTTATAGCATTGCGGGAATTAACCTAGGTTATAAATTTACTGATCATATGAGTGGTCGAGTAGGTATTAGCA
ATATTTTTGATGAAGATAAATTACGTGATCTTTCGGTCAGCCAAACTTATAATGAACCTGGTCGTGCGTATTATGCCAGC
TTAAAATATCAGTTTTAA

Upstream 100 bases:

>100_bases
TTGATAATAATTCTCAATATTATTTGTAATTTAATTTATTTTTGTTAGAATTGCCACGAAATTTAAGATTCATTTAATAT
TTGTAACAAAGGGGAAATGA

Downstream 100 bases:

>100_bases
GTACTTTTAAAAAGCCGTTTAACTTCATTAGATATTCCAAATATCGTGAGGTCAAATTACAAAGGCGGCTTTTTGTATTC
AAATATATTTATCATATTGC

Product: outer membrane receptor FepA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 725

Protein sequence:

>725_residues
MYKPLFRTVLSIAILSSMFSVAYAEETEQKDTQKLEKIILTAEEQIKQSLGVSVITAEDLERIPVVNDISEYLRKMPGVN
LTGNSSTGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRYGWRGERDTRGDSNWVPADAIESIEVIRGPAAARYGNG
AMGGVVNIKTKKVTNEAHGTLELYTNQPENSKEGDTNRVSLNLSGPLIKDILSYRIYGNFNKTKNDAVDINPLIPSSGYR
AAGREGFENKDLNARFAWQSTDNQTILFDLGSSRQGNLYAGDSQNSNLDPTANAILSELIDKETNTIWKDSYAITHEGKW
QWGDSRVIAQFDRTKNKRFAEGTAGAAEGRINNLDNRTTSTLDTIRLNGEVNIPLDIYVPQNLTLGTEWVEDHFKDPGNT
TQGTGSYADSLTSGDRSKMNSRIASAYIEDNLKITDSTDFVMGLRFDDHSKSGSNWSPSLNITQRLGDYFTLKGGIARAY
KAPNLYQNASGYLLATNGNGCPIGLTQCVLQGNDNLKPETSVNKEIGIQFQKDIVNASLAWFRNDYKDKISSGNEVTQQV
TIGGITYNVLQWTNIPKALVQGVEGNISLDWGNISWTNNLTYMVDSVDKQTGNPLSVIPKYTINSILNYQITDKTDVNFV
YTMYGRQKPRQYVETNLENSRGIATQSIRSYSIAGINLGYKFTDHMSGRVGISNIFDEDKLRDLSVSQTYNEPGRAYYAS
LKYQF

Sequences:

>Translated_725_residues
MYKPLFRTVLSIAILSSMFSVAYAEETEQKDTQKLEKIILTAEEQIKQSLGVSVITAEDLERIPVVNDISEYLRKMPGVN
LTGNSSTGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRYGWRGERDTRGDSNWVPADAIESIEVIRGPAAARYGNG
AMGGVVNIKTKKVTNEAHGTLELYTNQPENSKEGDTNRVSLNLSGPLIKDILSYRIYGNFNKTKNDAVDINPLIPSSGYR
AAGREGFENKDLNARFAWQSTDNQTILFDLGSSRQGNLYAGDSQNSNLDPTANAILSELIDKETNTIWKDSYAITHEGKW
QWGDSRVIAQFDRTKNKRFAEGTAGAAEGRINNLDNRTTSTLDTIRLNGEVNIPLDIYVPQNLTLGTEWVEDHFKDPGNT
TQGTGSYADSLTSGDRSKMNSRIASAYIEDNLKITDSTDFVMGLRFDDHSKSGSNWSPSLNITQRLGDYFTLKGGIARAY
KAPNLYQNASGYLLATNGNGCPIGLTQCVLQGNDNLKPETSVNKEIGIQFQKDIVNASLAWFRNDYKDKISSGNEVTQQV
TIGGITYNVLQWTNIPKALVQGVEGNISLDWGNISWTNNLTYMVDSVDKQTGNPLSVIPKYTINSILNYQITDKTDVNFV
YTMYGRQKPRQYVETNLENSRGIATQSIRSYSIAGINLGYKFTDHMSGRVGISNIFDEDKLRDLSVSQTYNEPGRAYYAS
LKYQF
>Mature_725_residues
MYKPLFRTVLSIAILSSMFSVAYAEETEQKDTQKLEKIILTAEEQIKQSLGVSVITAEDLERIPVVNDISEYLRKMPGVN
LTGNSSTGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNSVRYGWRGERDTRGDSNWVPADAIESIEVIRGPAAARYGNG
AMGGVVNIKTKKVTNEAHGTLELYTNQPENSKEGDTNRVSLNLSGPLIKDILSYRIYGNFNKTKNDAVDINPLIPSSGYR
AAGREGFENKDLNARFAWQSTDNQTILFDLGSSRQGNLYAGDSQNSNLDPTANAILSELIDKETNTIWKDSYAITHEGKW
QWGDSRVIAQFDRTKNKRFAEGTAGAAEGRINNLDNRTTSTLDTIRLNGEVNIPLDIYVPQNLTLGTEWVEDHFKDPGNT
TQGTGSYADSLTSGDRSKMNSRIASAYIEDNLKITDSTDFVMGLRFDDHSKSGSNWSPSLNITQRLGDYFTLKGGIARAY
KAPNLYQNASGYLLATNGNGCPIGLTQCVLQGNDNLKPETSVNKEIGIQFQKDIVNASLAWFRNDYKDKISSGNEVTQQV
TIGGITYNVLQWTNIPKALVQGVEGNISLDWGNISWTNNLTYMVDSVDKQTGNPLSVIPKYTINSILNYQITDKTDVNFV
YTMYGRQKPRQYVETNLENSRGIATQSIRSYSIAGINLGYKFTDHMSGRVGISNIFDEDKLRDLSVSQTYNEPGRAYYAS
LKYQF

Specific function: Specific receptor for the siderophore ferric enterobactin [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786798, Length=755, Percent_Identity=46.887417218543, Blast_Score=635, Evalue=0.0,
Organism=Escherichia coli, GI1788478, Length=745, Percent_Identity=30.8724832214765, Blast_Score=278, Evalue=9e-76,
Organism=Escherichia coli, GI1790405, Length=240, Percent_Identity=30.8333333333333, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 80533; Mature: 80533

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKPLFRTVLSIAILSSMFSVAYAEETEQKDTQKLEKIILTAEEQIKQSLGVSVITAEDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHH
ERIPVVNDISEYLRKMPGVNLTGNSSTGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNS
HHCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCC
VRYGWRGERDTRGDSNWVPADAIESIEVIRGPAAARYGNGAMGGVVNIKTKKVTNEAHGT
EEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEEEECCCCCCE
LELYTNQPENSKEGDTNRVSLNLSGPLIKDILSYRIYGNFNKTKNDAVDINPLIPSSGYR
EEEEECCCCCCCCCCCCEEEEEECCHHHHHHHHEEEEECCCCCCCCCEEECCCCCCCCCC
AAGREGFENKDLNARFAWQSTDNQTILFDLGSSRQGNLYAGDSQNSNLDPTANAILSELI
CCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
DKETNTIWKDSYAITHEGKWQWGDSRVIAQFDRTKNKRFAEGTAGAAEGRINNLDNRTTS
HCCCCCEECCCEEEEECCCEEECCCCEEEEEHHCCCCEECCCCCCCCCCCCCCCCCCCCC
TLDTIRLNGEVNIPLDIYVPQNLTLGTEWVEDHFKDPGNTTQGTGSYADSLTSGDRSKMN
CEEEEEECCEEECCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHH
SRIASAYIEDNLKITDSTDFVMGLRFDDHSKSGSNWSPSLNITQRLGDYFTLKGGIARAY
HHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCCEEEECCCHHHHH
KAPNLYQNASGYLLATNGNGCPIGLTQCVLQGNDNLKPETSVNKEIGIQFQKDIVNASLA
CCCCCCCCCCCEEEEECCCCCCCCHHHHEEECCCCCCCCCCCCHHHCCEEHHHHHHHHHH
WFRNDYKDKISSGNEVTQQVTIGGITYNVLQWTNIPKALVQGVEGNISLDWGNISWTNNL
HHHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCHHHHCCCCCCEEEECCCEEECCCE
TYMVDSVDKQTGNPLSVIPKYTINSILNYQITDKTDVNFVYTMYGRQKPRQYVETNLENS
EEEEECCCCCCCCCEEEECCHHHHHHEEEEECCCCCCCEEEEECCCCCCHHHHHCCCCCC
RGIATQSIRSYSIAGINLGYKFTDHMSGRVGISNIFDEDKLRDLSVSQTYNEPGRAYYAS
CCCCHHHHCEEEEEEEEECEEECCCCCCCCCHHHHCCCHHHCCCCHHHCCCCCCCEEEEE
LKYQF
EEECC
>Mature Secondary Structure
MYKPLFRTVLSIAILSSMFSVAYAEETEQKDTQKLEKIILTAEEQIKQSLGVSVITAEDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHH
ERIPVVNDISEYLRKMPGVNLTGNSSTGQRGNNRQIDIRGMGPENTLILIDGKPVTSRNS
HHCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCC
VRYGWRGERDTRGDSNWVPADAIESIEVIRGPAAARYGNGAMGGVVNIKTKKVTNEAHGT
EEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCHHCCCCCCCCCEEEEEEEEECCCCCCE
LELYTNQPENSKEGDTNRVSLNLSGPLIKDILSYRIYGNFNKTKNDAVDINPLIPSSGYR
EEEEECCCCCCCCCCCCEEEEEECCHHHHHHHHEEEEECCCCCCCCCEEECCCCCCCCCC
AAGREGFENKDLNARFAWQSTDNQTILFDLGSSRQGNLYAGDSQNSNLDPTANAILSELI
CCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCEEECCCCCCCCCHHHHHHHHHHH
DKETNTIWKDSYAITHEGKWQWGDSRVIAQFDRTKNKRFAEGTAGAAEGRINNLDNRTTS
HCCCCCEECCCEEEEECCCEEECCCCEEEEEHHCCCCEECCCCCCCCCCCCCCCCCCCCC
TLDTIRLNGEVNIPLDIYVPQNLTLGTEWVEDHFKDPGNTTQGTGSYADSLTSGDRSKMN
CEEEEEECCEEECCEEEEECCCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHCCCCHHHHH
SRIASAYIEDNLKITDSTDFVMGLRFDDHSKSGSNWSPSLNITQRLGDYFTLKGGIARAY
HHHHHHHHHCCCEEECCCCEEEEEEECCCCCCCCCCCCCCCHHHHCCCEEEECCCHHHHH
KAPNLYQNASGYLLATNGNGCPIGLTQCVLQGNDNLKPETSVNKEIGIQFQKDIVNASLA
CCCCCCCCCCCEEEEECCCCCCCCHHHHEEECCCCCCCCCCCCHHHCCEEHHHHHHHHHH
WFRNDYKDKISSGNEVTQQVTIGGITYNVLQWTNIPKALVQGVEGNISLDWGNISWTNNL
HHHHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCHHHHCCCCCCEEEECCCEEECCCE
TYMVDSVDKQTGNPLSVIPKYTINSILNYQITDKTDVNFVYTMYGRQKPRQYVETNLENS
EEEEECCCCCCCCCEEEECCHHHHHHEEEEECCCCCCCEEEEECCCCCCHHHHHCCCCCC
RGIATQSIRSYSIAGINLGYKFTDHMSGRVGISNIFDEDKLRDLSVSQTYNEPGRAYYAS
CCCCHHHHCEEEEEEEEECEEECCCCCCCCCHHHHCCCHHHCCCCHHHCCCCCCCEEEEE
LKYQF
EEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419284; 10984043 [H]