BacMap

Definition	Acinetobacter sp. ADP1 chromosome, complete genome.
Accession	NC_005966
Length	3,598,621

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The map label for this gene is fbp [H]

Identifier: 50084230

GI number: 50084230

Start: 1019796

End: 1020131

Strand: Direct

Name: fbp [H]

Synonym: ACIAD1028

Alternate gene names: 50084230

Gene position: 1019796-1020131 (Clockwise)

Preceding gene: 50084229

Following gene: 50084231

Centisome position: 28.34

GC content: 37.8

Gene sequence:

>336_bases
ATGCAAGAATTACAGATTATTGATTTAAAAGTAGGTGAAGGTAAAGAAGCGGTAAAAGGTGCTTTAATTACAACGCACTA
CACAGGATGGCTCGAAGATGGCACTAAATTTGATGCTTCTATAGATCGCGGTAATTACTTTGAATGTGTAATTGGTACTG
GACGAGTCATTAAAGGCTGGGATCAGGGTATTATAGGTATGAAAGTAGGCGGAAAACGTAAGTTGATCGTGCCTGCACAT
CTGGCTTACGGTGAGCGCAAGATGGGAAACATCATTCCTGCAAATTCTAATTTGATTTTTGAAATTGAATTATTTGATGT
AAAAACCCGTGATTAA

Upstream 100 bases:

>100_bases
TTATTGAATGATCATGAACAGGTTGATGTTTCATGGACAAAATTGCATTAAGTACAACATGGTTTAAATAGACAGAATTT
ATATTAAAGGTAGACATGCT

Downstream 100 bases:

>100_bases
ACCAGGATTATAAAAAAGCCCATTCTGGGCTTTTTTATAGTCACTATAATTTTTAGATTATATTAATGAGTTTTATATTT
TAAATTTTGATAAGCTTATT

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MQELQIIDLKVGEGKEAVKGALITTHYTGWLEDGTKFDASIDRGNYFECVIGTGRVIKGWDQGIIGMKVGGKRKLIVPAH
LAYGERKMGNIIPANSNLIFEIELFDVKTRD

Sequences:

>Translated_111_residues
MQELQIIDLKVGEGKEAVKGALITTHYTGWLEDGTKFDASIDRGNYFECVIGTGRVIKGWDQGIIGMKVGGKRKLIVPAH
LAYGERKMGNIIPANSNLIFEIELFDVKTRD
>Mature_111_residues
MQELQIIDLKVGEGKEAVKGALITTHYTGWLEDGTKFDASIDRGNYFECVIGTGRVIKGWDQGIIGMKVGGKRKLIVPAH
LAYGERKMGNIIPANSNLIFEIELFDVKTRD

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cytoplasm And Periplasmic Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=92, Percent_Identity=51.0869565217391, Blast_Score=103, Evalue=3e-23,
Organism=Homo sapiens, GI17149844, Length=92, Percent_Identity=51.0869565217391, Blast_Score=103, Evalue=3e-23,
Organism=Homo sapiens, GI17149842, Length=92, Percent_Identity=51.0869565217391, Blast_Score=103, Evalue=3e-23,
Organism=Homo sapiens, GI192448443, Length=97, Percent_Identity=42.2680412371134, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI4503729, Length=101, Percent_Identity=45.5445544554455, Blast_Score=87, Evalue=4e-18,
Organism=Homo sapiens, GI17149836, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI4503725, Length=106, Percent_Identity=38.6792452830189, Blast_Score=85, Evalue=2e-17,
Organism=Homo sapiens, GI33469985, Length=88, Percent_Identity=45.4545454545455, Blast_Score=83, Evalue=4e-17,
Organism=Homo sapiens, GI4758380, Length=106, Percent_Identity=37.7358490566038, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI224809329, Length=109, Percent_Identity=42.2018348623853, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI224809327, Length=109, Percent_Identity=42.2018348623853, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI4758384, Length=109, Percent_Identity=42.2018348623853, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI224809331, Length=103, Percent_Identity=42.7184466019417, Blast_Score=76, Evalue=6e-15,
Organism=Homo sapiens, GI150010552, Length=110, Percent_Identity=40.9090909090909, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI206725547, Length=97, Percent_Identity=42.2680412371134, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI8923659, Length=95, Percent_Identity=43.1578947368421, Blast_Score=70, Evalue=3e-13,
Organism=Homo sapiens, GI31317231, Length=98, Percent_Identity=41.8367346938776, Blast_Score=68, Evalue=2e-12,
Organism=Homo sapiens, GI7706131, Length=92, Percent_Identity=36.9565217391304, Blast_Score=67, Evalue=3e-12,
Organism=Homo sapiens, GI4503727, Length=97, Percent_Identity=36.0824742268041, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI87082390, Length=104, Percent_Identity=42.3076923076923, Blast_Score=80, Evalue=2e-17,
Organism=Escherichia coli, GI1789745, Length=100, Percent_Identity=39, Blast_Score=60, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17540882, Length=93, Percent_Identity=48.3870967741936, Blast_Score=93, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71993519, Length=88, Percent_Identity=52.2727272727273, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17561782, Length=109, Percent_Identity=40.3669724770642, Blast_Score=80, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17561778, Length=90, Percent_Identity=42.2222222222222, Blast_Score=68, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71993555, Length=75, Percent_Identity=45.3333333333333, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324194, Length=107, Percent_Identity=48.5981308411215, Blast_Score=107, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320727, Length=95, Percent_Identity=52.6315789473684, Blast_Score=103, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6323566, Length=103, Percent_Identity=43.6893203883495, Blast_Score=86, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6323482, Length=103, Percent_Identity=42.7184466019417, Blast_Score=83, Evalue=1e-17,
Organism=Drosophila melanogaster, GI281363946, Length=94, Percent_Identity=47.8723404255319, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17352457, Length=94, Percent_Identity=47.8723404255319, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24655568, Length=106, Percent_Identity=45.2830188679245, Blast_Score=100, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24647110, Length=101, Percent_Identity=45.5445544554455, Blast_Score=92, Evalue=6e-20,
Organism=Drosophila melanogaster, GI21356629, Length=98, Percent_Identity=45.9183673469388, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24583150, Length=104, Percent_Identity=41.3461538461538, Blast_Score=79, Evalue=7e-16,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 12309; Mature: 12309

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQELQIIDLKVGEGKEAVKGALITTHYTGWLEDGTKFDASIDRGNYFECVIGTGRVIKGW
CCCEEEEEEEECCCCHHHCCEEEEEEEEEECCCCCEEEEEECCCCEEEEEEECCEEEECC
DQGIIGMKVGGKRKLIVPAHLAYGERKMGNIIPANSNLIFEIELFDVKTRD
CCCEEEEEECCCEEEEEECCCCCCCCCCCCEEECCCCEEEEEEEEEEEECC
>Mature Secondary Structure
MQELQIIDLKVGEGKEAVKGALITTHYTGWLEDGTKFDASIDRGNYFECVIGTGRVIKGW
CCCEEEEEEEECCCCHHHCCEEEEEEEEEECCCCCEEEEEECCCCEEEEEEECCEEEECC
DQGIIGMKVGGKRKLIVPAHLAYGERKMGNIIPANSNLIFEIELFDVKTRD
CCCEEEEEECCCEEEEEECCCCCCCCCCCCEEECCCCEEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]