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The map label for this gene is nadX

Identifier: 50084200

GI number: 50084200

Start: 981843

End: 982634

Strand: Direct

Name: nadX

Synonym: ACIAD0997

Alternate gene names: 50084200

Gene position: 981843-982634 (Clockwise)

Preceding gene: 50084199

Following gene: 50084201

Centisome position: 27.28

GC content: 45.71

Gene sequence:

>792_bases
ATGAAGCAATTAATGATGATTGGTTTTGGTGCAATGGCCTCGGAAGTCTATGCACATTTACCACAAGATCTTGAGTTGAA
GTGGATTGTGGTTCCCGAGCGGAGTGTTGAAAGCGTCAAGCAAAAAGTTGATCGCCACATACAGGTGATTTCCGATATCA
ATCAGTGTGACGGTGCGCCAGATTATGTGATTGAGGTGGCAGGGCAGGCAGCAGTAAAAGAGCATGCAAAAAACGTACTG
GCGCATGGCTGGAATATAGGGTTGATTTCGGTTGGAACCTTGGCAGATAGCGAGTTTTTTACGGAATTACAGCAAACAGC
AGAACAAAATGGTGCGCATTTACATCTACTTGCAGGTGCAATTGCTGGGATTGATGGAATTGCAGCAGCGAAAGAAGGCG
GCTTGGAAAAAGTGACCTACAAAGGCTGCAAAAGTCCAAATAGTTGGCGTGGCAGTTATGCCGAGCAGTTAATTGATTTG
GATCAGGTACATACAGTGACCATGTTCTATCGAGGAACTGCGCGTGAGGCTGCACAAAAATTTCCTGCAAATGCCAATGT
TGCAGCAACCATTGCACTGGCAGGCGTTGGCATGGACAACACTATCGTAGAACTGACTGTTGATCCAGATACCACTCAAA
ACAAACATACTATTGTTGCCGAAGGTCGATTTGGTCAAATGACCATTGAAATGGTCGGTGTACCACTCGCATCTAACCCA
AAAACATCGACACTGGCTGCACTCAGCGTGATTCGTGCTTGCCGTAACAGTGTTGAAGCCATTCAGATTTAA

Upstream 100 bases:

>100_bases
GTGCCTTGGTCTTTCTGGCTTCGCCATTGGCCTCTTATACCACGGGCTCAACCATTGATGTCTCTGGTGGTTTCAACAAA
CACTTATAAGGGTGAGCGCA

Downstream 100 bases:

>100_bases
GAGGGATATTCAGATGGTTAAGGAACTTTATATTGCAGGTGAATGGCGTTTGGGTCGAGGAAAGGTTATCCAAAGTACTT
TTCCAGCAGATAATTCTGTA

Product: L-aspartate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MKQLMMIGFGAMASEVYAHLPQDLELKWIVVPERSVESVKQKVDRHIQVISDINQCDGAPDYVIEVAGQAAVKEHAKNVL
AHGWNIGLISVGTLADSEFFTELQQTAEQNGAHLHLLAGAIAGIDGIAAAKEGGLEKVTYKGCKSPNSWRGSYAEQLIDL
DQVHTVTMFYRGTAREAAQKFPANANVAATIALAGVGMDNTIVELTVDPDTTQNKHTIVAEGRFGQMTIEMVGVPLASNP
KTSTLAALSVIRACRNSVEAIQI

Sequences:

>Translated_263_residues
MKQLMMIGFGAMASEVYAHLPQDLELKWIVVPERSVESVKQKVDRHIQVISDINQCDGAPDYVIEVAGQAAVKEHAKNVL
AHGWNIGLISVGTLADSEFFTELQQTAEQNGAHLHLLAGAIAGIDGIAAAKEGGLEKVTYKGCKSPNSWRGSYAEQLIDL
DQVHTVTMFYRGTAREAAQKFPANANVAATIALAGVGMDNTIVELTVDPDTTQNKHTIVAEGRFGQMTIEMVGVPLASNP
KTSTLAALSVIRACRNSVEAIQI
>Mature_263_residues
MKQLMMIGFGAMASEVYAHLPQDLELKWIVVPERSVESVKQKVDRHIQVISDINQCDGAPDYVIEVAGQAAVKEHAKNVL
AHGWNIGLISVGTLADSEFFTELQQTAEQNGAHLHLLAGAIAGIDGIAAAKEGGLEKVTYKGCKSPNSWRGSYAEQLIDL
DQVHTVTMFYRGTAREAAQKFPANANVAATIALAGVGMDNTIVELTVDPDTTQNKHTIVAEGRFGQMTIEMVGVPLASNP
KTSTLAALSVIRACRNSVEAIQI

Specific function: Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate

COG id: COG1712

COG function: function code R; Predicted dinucleotide-utilizing enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L-aspartate dehydrogenase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ASPD_ACIAD (Q6FDH0)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045710.1
- ProteinModelPortal:   Q6FDH0
- SMR:   Q6FDH0
- STRING:   Q6FDH0
- GeneID:   2880590
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0997
- NMPDR:   fig|62977.3.peg.1048
- eggNOG:   COG1712
- HOGENOM:   HBG649642
- OMA:   ECAGHSA
- ProtClustDB:   PRK13303
- BioCyc:   ASP62977:ACIAD0997-MONOMER
- HAMAP:   MF_01265
- InterPro:   IPR005106
- InterPro:   IPR002811
- InterPro:   IPR011182
- InterPro:   IPR020626
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF005227

Pfam domain/function: PF01958 DUF108; PF03447 NAD_binding_3

EC number: =1.4.1.21

Molecular weight: Translated: 28222; Mature: 28222

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: ACT_SITE 216-216 BINDING 120-120 BINDING 186-186

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLMMIGFGAMASEVYAHLPQDLELKWIVVPERSVESVKQKVDRHIQVISDINQCDGAP
CCCEEEECCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCC
DYVIEVAGQAAVKEHAKNVLAHGWNIGLISVGTLADSEFFTELQQTAEQNGAHLHLLAGA
CCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHH
IAGIDGIAAAKEGGLEKVTYKGCKSPNSWRGSYAEQLIDLDQVHTVTMFYRGTAREAAQK
HHCCCHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHH
FPANANVAATIALAGVGMDNTIVELTVDPDTTQNKHTIVAEGRFGQMTIEMVGVPLASNP
CCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEEEECCCCCEEEEEEEECCCCCCC
KTSTLAALSVIRACRNSVEAIQI
CHHHHHHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MKQLMMIGFGAMASEVYAHLPQDLELKWIVVPERSVESVKQKVDRHIQVISDINQCDGAP
CCCEEEECCHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCC
DYVIEVAGQAAVKEHAKNVLAHGWNIGLISVGTLADSEFFTELQQTAEQNGAHLHLLAGA
CCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEHHH
IAGIDGIAAAKEGGLEKVTYKGCKSPNSWRGSYAEQLIDLDQVHTVTMFYRGTAREAAQK
HHCCCHHHHHCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHEEEEEEECCCHHHHHHH
FPANANVAATIALAGVGMDNTIVELTVDPDTTQNKHTIVAEGRFGQMTIEMVGVPLASNP
CCCCCCCEEEEEEEECCCCCEEEEEEECCCCCCCCEEEEECCCCCEEEEEEEECCCCCCC
KTSTLAALSVIRACRNSVEAIQI
CHHHHHHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA