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The map label for this gene is foxA [H]

Identifier: 50084177

GI number: 50084177

Start: 959235

End: 961349

Strand: Direct

Name: foxA [H]

Synonym: ACIAD0973

Alternate gene names: 50084177

Gene position: 959235-961349 (Clockwise)

Preceding gene: 50084173

Following gene: 50084179

Centisome position: 26.66

GC content: 39.57

Gene sequence:

>2115_bases
ATGACGACTTTCTCTTCTCAATCAATATTCGGTATGACTTGTTTATGGTTAAGTATTCAACTGGTATATGCGCAAGATCT
ACAGGTCTTGAATGCAATTCAGTTGACTGCAACAGCTCAAAAAAATTCGTTTTTAGAGGAGCCTGAAAGCGCGGCTACGA
AGTTTGTGCTAGATCCATTAAAAACGCCGCAAAATGTACAGGTCGTCAATCAGAAAATGATTGAGGATATAAACGCTCAA
CGTATCAGTGATGTGGTTGGCCTAGTGAGTGGTGTCAGTTTACTTAATCCAACAGGAGGAATATGGGATAACTATTCATT
TCGAGGATTCAACACAGACCAAACCATTGGTGTAGCAAGCCTTAGAAATGGATTAACGTCATATTTAGGGTTTAATGTTG
CACATGATCTGGTCAATGTAGAACGAATTGAATTTTTAAAAGGGCCAGAGGCAGCATTATATGGTGCTGGAGAGCCTGGT
GGTGTTTTAAATATTGTGACCAAAAAGCCAGAATTTGAACCACACCATAGCATTGAATTACGAGGCGGATCTTATAACCA
GTATCGTAGTGCTATAGATTCAACCAATGCGATTACAGAAACAATCGCCTATCGTTTGGGTGTGGCTTATGAAAATAACA
AAAGCTTCCGTGATGAAGTGCAAAACAATAAATTATTTGTTGCACCACAACTGACATGGAAGCCAAGTGACACTACTCAG
GTTGATTACGACAGTGAATATACCGTGCTAAATACGTTGTTTGATCGTGGAGTTCTTGCAGTCAATCAGCAGTTAGGAGC
GATTCCGAACTCAAGATTTCTGGGCGAAAAAGACGATGGTCTGATGACCGTGAATGACTATTTACAACAGGTCAGAATCC
AGCATCAGTGGAATCCAATGTGGTCGACTCAGACCATCCTCAACTATAAAGATAATACATGGCGTGGTTTTTCTTCGGAA
GCTTATCAGCTCTTAAATGCACAAGGTGATTTAAACCGTGAACGCCGTTATCGTATCTATGACACCACCAGCTATTTGTT
CAGTCATGATTTAACTGGGCAGTTCAATACAGGTTCGTTAAATCATCGACTTTTTATAGGCATGACCTATAGTGATTTAA
AAGTACAGAATCATTTGCTTAGATACAGAAAAAAGGGATCGACGAGCAGTGAAATCAATATTTATGATCCTATCTATGGC
GTTAATCTTCCAGCCGTTACTTCGGTCTATAACACGCTTGAGCGTCAAAAAAATGCAGCTTTGAGTTTAAGTGATTACAT
CGAGATTAATCCAAAATGGGCAGTTTTACTGGGTGGACGTTACGATTACTATCAGCAAGACTATCGTGAATTTATTGCGG
GCATTCAGGGCGGTCAGTATTTCATGCATTTTAGCCCTAAAGTCGCTGTCAATTATTTGCTTGATGATCATGCTTCACTG
TTTGCCAGCGTGGGACAGTCGTTTCATCTTAATTCAGGACTGGATATTCAGCAGCAACCATTCAAACCCGAAAAAGCATG
GACTTATGAGCTAGGCACCAAAGCAAAATGGCTAGATGATCGTATCATGGCTTCTGTATCACTTTTTCATGTCAAAAAGC
AGAATGTCTTGACGACTAATCCATTGAATTCGGCTTATATGATGCCAGTGGGCCAAGAAACGAGTCGTGGTATTGAATTT
GATCTCACTGCACAGCCAGTCGACCCGCTTAACTTAAAGTTTGCATATGCCTATACGGATGCGATTGTTTCTAAAAGCGA
AGAAAGCTCAGGAATTGCAAAGGGCAGTGCTTTACTCAATAGCCCTAAACATCATCTTAACTTATTGGTGATGTATGATG
TATGGCAAGCAGGAGCAAGTAAAATTGGCTTAGGCGGGAATATTCAGTATGTTTCGGCGCGTACAGGTAATGTCTATGAC
AATGGTTTTAATTTACCATCTTATACCTTGTTGAACTTAAATAGTTACTATCAGATGAATCCAAAACTCAAATTACAGCT
TAATTTGAATAATCTATTTAACACTATATATTATACTGCCAGTGTAAAGGATGAATGGGTGGCCCCAGGGCATCCGAGAG
AAATATTTCTAAGCATCAATTATCAATTTAATTAA

Upstream 100 bases:

>100_bases
GAAAACTAAGAAGACCAGTAAGTCAATTAACTTATACAATCTTGTGTACAAGATGGTATTTTATTGTAATTTACCACAAT
TGCAACATTCGGTTTTTTTC

Downstream 100 bases:

>100_bases
ATAGATTAAACCAGAAGCATAATACTTCTGGTTTTTTCAAGTTCAATGGATTGGCATGCGGTACTGGATCATTTCAGATT
TTTCAGCGACCCAGTTATAG

Product: ferrichrome-iron receptor protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 704; Mature: 703

Protein sequence:

>704_residues
MTTFSSQSIFGMTCLWLSIQLVYAQDLQVLNAIQLTATAQKNSFLEEPESAATKFVLDPLKTPQNVQVVNQKMIEDINAQ
RISDVVGLVSGVSLLNPTGGIWDNYSFRGFNTDQTIGVASLRNGLTSYLGFNVAHDLVNVERIEFLKGPEAALYGAGEPG
GVLNIVTKKPEFEPHHSIELRGGSYNQYRSAIDSTNAITETIAYRLGVAYENNKSFRDEVQNNKLFVAPQLTWKPSDTTQ
VDYDSEYTVLNTLFDRGVLAVNQQLGAIPNSRFLGEKDDGLMTVNDYLQQVRIQHQWNPMWSTQTILNYKDNTWRGFSSE
AYQLLNAQGDLNRERRYRIYDTTSYLFSHDLTGQFNTGSLNHRLFIGMTYSDLKVQNHLLRYRKKGSTSSEINIYDPIYG
VNLPAVTSVYNTLERQKNAALSLSDYIEINPKWAVLLGGRYDYYQQDYREFIAGIQGGQYFMHFSPKVAVNYLLDDHASL
FASVGQSFHLNSGLDIQQQPFKPEKAWTYELGTKAKWLDDRIMASVSLFHVKKQNVLTTNPLNSAYMMPVGQETSRGIEF
DLTAQPVDPLNLKFAYAYTDAIVSKSEESSGIAKGSALLNSPKHHLNLLVMYDVWQAGASKIGLGGNIQYVSARTGNVYD
NGFNLPSYTLLNLNSYYQMNPKLKLQLNLNNLFNTIYYTASVKDEWVAPGHPREIFLSINYQFN

Sequences:

>Translated_704_residues
MTTFSSQSIFGMTCLWLSIQLVYAQDLQVLNAIQLTATAQKNSFLEEPESAATKFVLDPLKTPQNVQVVNQKMIEDINAQ
RISDVVGLVSGVSLLNPTGGIWDNYSFRGFNTDQTIGVASLRNGLTSYLGFNVAHDLVNVERIEFLKGPEAALYGAGEPG
GVLNIVTKKPEFEPHHSIELRGGSYNQYRSAIDSTNAITETIAYRLGVAYENNKSFRDEVQNNKLFVAPQLTWKPSDTTQ
VDYDSEYTVLNTLFDRGVLAVNQQLGAIPNSRFLGEKDDGLMTVNDYLQQVRIQHQWNPMWSTQTILNYKDNTWRGFSSE
AYQLLNAQGDLNRERRYRIYDTTSYLFSHDLTGQFNTGSLNHRLFIGMTYSDLKVQNHLLRYRKKGSTSSEINIYDPIYG
VNLPAVTSVYNTLERQKNAALSLSDYIEINPKWAVLLGGRYDYYQQDYREFIAGIQGGQYFMHFSPKVAVNYLLDDHASL
FASVGQSFHLNSGLDIQQQPFKPEKAWTYELGTKAKWLDDRIMASVSLFHVKKQNVLTTNPLNSAYMMPVGQETSRGIEF
DLTAQPVDPLNLKFAYAYTDAIVSKSEESSGIAKGSALLNSPKHHLNLLVMYDVWQAGASKIGLGGNIQYVSARTGNVYD
NGFNLPSYTLLNLNSYYQMNPKLKLQLNLNNLFNTIYYTASVKDEWVAPGHPREIFLSINYQFN
>Mature_703_residues
TTFSSQSIFGMTCLWLSIQLVYAQDLQVLNAIQLTATAQKNSFLEEPESAATKFVLDPLKTPQNVQVVNQKMIEDINAQR
ISDVVGLVSGVSLLNPTGGIWDNYSFRGFNTDQTIGVASLRNGLTSYLGFNVAHDLVNVERIEFLKGPEAALYGAGEPGG
VLNIVTKKPEFEPHHSIELRGGSYNQYRSAIDSTNAITETIAYRLGVAYENNKSFRDEVQNNKLFVAPQLTWKPSDTTQV
DYDSEYTVLNTLFDRGVLAVNQQLGAIPNSRFLGEKDDGLMTVNDYLQQVRIQHQWNPMWSTQTILNYKDNTWRGFSSEA
YQLLNAQGDLNRERRYRIYDTTSYLFSHDLTGQFNTGSLNHRLFIGMTYSDLKVQNHLLRYRKKGSTSSEINIYDPIYGV
NLPAVTSVYNTLERQKNAALSLSDYIEINPKWAVLLGGRYDYYQQDYREFIAGIQGGQYFMHFSPKVAVNYLLDDHASLF
ASVGQSFHLNSGLDIQQQPFKPEKAWTYELGTKAKWLDDRIMASVSLFHVKKQNVLTTNPLNSAYMMPVGQETSRGIEFD
LTAQPVDPLNLKFAYAYTDAIVSKSEESSGIAKGSALLNSPKHHLNLLVMYDVWQAGASKIGLGGNIQYVSARTGNVYDN
GFNLPSYTLLNLNSYYQMNPKLKLQLNLNNLFNTIYYTASVKDEWVAPGHPREIFLSINYQFN

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=681, Percent_Identity=24.0822320117474, Blast_Score=173, Evalue=4e-44,
Organism=Escherichia coli, GI1787024, Length=768, Percent_Identity=21.875, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1787344, Length=279, Percent_Identity=26.5232974910394, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1790743, Length=345, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79464; Mature: 79333

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFSSQSIFGMTCLWLSIQLVYAQDLQVLNAIQLTATAQKNSFLEEPESAATKFVLDPL
CCCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHEEEEEECHHCCCCCCCHHHHHHEEECCC
KTPQNVQVVNQKMIEDINAQRISDVVGLVSGVSLLNPTGGIWDNYSFRGFNTDQTIGVAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCEECCCCCCCCCHHHH
LRNGLTSYLGFNVAHDLVNVERIEFLKGPEAALYGAGEPGGVLNIVTKKPEFEPHHSIEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCCCCCEEEE
RGGSYNQYRSAIDSTNAITETIAYRLGVAYENNKSFRDEVQNNKLFVAPQLTWKPSDTTQ
ECCCCHHHHHHHCCCHHHHHHHHHHHEEEECCCCHHHHHHCCCEEEEEEEEEECCCCCCE
VDYDSEYTVLNTLFDRGVLAVNQQLGAIPNSRFLGEKDDGLMTVNDYLQQVRIQHQWNPM
ECCCCCHHHHHHHHHCCEEEECHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCC
WSTQTILNYKDNTWRGFSSEAYQLLNAQGDLNRERRYRIYDTTSYLFSHDLTGQFNTGSL
CCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECHHHHHCCCCCCCCCCCCC
NHRLFIGMTYSDLKVQNHLLRYRKKGSTSSEINIYDPIYGVNLPAVTSVYNTLERQKNAA
CCEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCE
LSLSDYIEINPKWAVLLGGRYDYYQQDYREFIAGIQGGQYFMHFSPKVAVNYLLDDHASL
EEEEHEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEHHHHHHH
FASVGQSFHLNSGLDIQQQPFKPEKAWTYELGTKAKWLDDRIMASVSLFHVKKQNVLTTN
HHHCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHEEEEECCCEEEEC
PLNSAYMMPVGQETSRGIEFDLTAQPVDPLNLKFAYAYTDAIVSKSEESSGIAKGSALLN
CCCCEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHCCCCCCCCCCCCHHHHC
SPKHHLNLLVMYDVWQAGASKIGLGGNIQYVSARTGNVYDNGFNLPSYTLLNLNSYYQMN
CCHHHEEEEEEEEEHHCCCCEECCCCCEEEEEECCCCEECCCCCCCCEEEEECCCEEEEC
PKLKLQLNLNNLFNTIYYTASVKDEWVAPGHPREIFLSINYQFN
CCEEEEEEHHHHEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
TTFSSQSIFGMTCLWLSIQLVYAQDLQVLNAIQLTATAQKNSFLEEPESAATKFVLDPL
CCCCCCCHHHHHEEEHHHHHHHHHHHHHHHHEEEEEECHHCCCCCCCHHHHHHEEECCC
KTPQNVQVVNQKMIEDINAQRISDVVGLVSGVSLLNPTGGIWDNYSFRGFNTDQTIGVAS
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCCCCCEECCCCCCCCCHHHH
LRNGLTSYLGFNVAHDLVNVERIEFLKGPEAALYGAGEPGGVLNIVTKKPEFEPHHSIEL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEEECCCCCCCCCEEEE
RGGSYNQYRSAIDSTNAITETIAYRLGVAYENNKSFRDEVQNNKLFVAPQLTWKPSDTTQ
ECCCCHHHHHHHCCCHHHHHHHHHHHEEEECCCCHHHHHHCCCEEEEEEEEEECCCCCCE
VDYDSEYTVLNTLFDRGVLAVNQQLGAIPNSRFLGEKDDGLMTVNDYLQQVRIQHQWNPM
ECCCCCHHHHHHHHHCCEEEECHHHCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCC
WSTQTILNYKDNTWRGFSSEAYQLLNAQGDLNRERRYRIYDTTSYLFSHDLTGQFNTGSL
CCCEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCEEEEEECHHHHHCCCCCCCCCCCCC
NHRLFIGMTYSDLKVQNHLLRYRKKGSTSSEINIYDPIYGVNLPAVTSVYNTLERQKNAA
CCEEEEEEEHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCE
LSLSDYIEINPKWAVLLGGRYDYYQQDYREFIAGIQGGQYFMHFSPKVAVNYLLDDHASL
EEEEHEEEECCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEHHHHHHH
FASVGQSFHLNSGLDIQQQPFKPEKAWTYELGTKAKWLDDRIMASVSLFHVKKQNVLTTN
HHHCCCCEECCCCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHEEEEECCCEEEEC
PLNSAYMMPVGQETSRGIEFDLTAQPVDPLNLKFAYAYTDAIVSKSEESSGIAKGSALLN
CCCCEEEECCCCCCCCCEEEEEECCCCCCCCEEEEEEEHHHHHCCCCCCCCCCCCHHHHC
SPKHHLNLLVMYDVWQAGASKIGLGGNIQYVSARTGNVYDNGFNLPSYTLLNLNSYYQMN
CCHHHEEEEEEEEEHHCCCCEECCCCCEEEEEECCCCEECCCCCCCCEEEEECCCEEEEC
PKLKLQLNLNNLFNTIYYTASVKDEWVAPGHPREIFLSINYQFN
CCEEEEEEHHHHEEEEEEEEECCCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]