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The map label for this gene is fabD [H]

Identifier: 50084081

GI number: 50084081

Start: 854146

End: 855132

Strand: Direct

Name: fabD [H]

Synonym: ACIAD0870

Alternate gene names: 50084081

Gene position: 854146-855132 (Clockwise)

Preceding gene: 50084080

Following gene: 50084082

Centisome position: 23.74

GC content: 45.19

Gene sequence:

>987_bases
ATGTCTGCTAAACGACTCGATCAAGTCGCTCAAGCAACTAAAACTGCATTTGTGTTTCCTGGTCAGGGTTCGCAAAAAGT
CGGCATGCTCGCTGAACTTGCAGAACAGTTTAGTGGTGTGCAAGAAACCTTTGCCGAGGCTTCTGATGCAGTCGGTTTTG
ATTTGTGGCACATTGCGCAAAGTGGTGAAGGGTTAGATCAAACTGAAAATACTCAACCCGTGTTACTAACTGCCAGTATT
GCATTGTGGCGTGTATGGCTAGACTTGGGTGGTTTAGCGCCTAAATATATGGCTGGACACTCTTTGGGTGAATACAGTGC
TTTGGTTGCCGCAGGTGCTTTATCATTAGGTGATGCAGCAAAGCTTGTTAATCTGCGCGGTAAACTGATGCAGAGTGCTG
TACCTCAGGGTGTTGGTGCAATGGCTGCAATTTTGGGGTTGCCTGACGAAAAAGTCATTGAATTGTGTCAGGCTGTCACT
GCTTCAGGTGACGGTTCTGTTGAGGCTGCCAATTATAATTCACAAGGTCAGGTGGTGATTGCTGGTTCTGCTGCTTTGGT
CAATGAAGTCATGACTCAGGCAAAAGAGCAGTCGGGCAAAGCCATTGCATTGCCTGTTTCGGTTCCATCACACTGTTCAT
TGATGAAGCCAGCGGCAGAAAAATTTGCCGAAGCATTGGAACAAACTGCCATTGAGCTACCAAGCCTTCCTGTAATACAA
AATGTAAATGCAGGAATTGCGACAGATGTGACTCAATTGCGCCAAGCTTTAACTGCGCAATTGTATCAGTCTGTACAGTG
GACTCGTACCATGCAATATTTGCAAGATCAGGGAATTCAGTACGTGGTTGAATGTGGTCCCGGTACAGTACTGAGTAATC
TTGCAAAACGTTTACCAAATATAGAAAAAGCATTTGCGATTGATAGCAAAAGTCGTATGGAAGATGCCCTAAACGCAGTT
TTAGTGGCTGAAGGAAAAATTGCATGA

Upstream 100 bases:

>100_bases
AAGCTCCCTTTTTTTGTTGTTTTTCGCAATTATAAAATCTTTTAAATAATGATAAATTCCCCCAACAGAAATAAGTAAAG
ACCAAATAAAGGATTTTTAT

Downstream 100 bases:

>100_bases
CACAACAACGTAAAGTTGCATTAGTCACAGGCGCAAGCCGTGGAATTGGTGCAGCAATTGCAGAACAGCTCATTCAAGAC
GGTTTTTTTGTTGTTGGAAC

Product: malonyl-CoA-[acyl-carrier-protein] transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MSAKRLDQVAQATKTAFVFPGQGSQKVGMLAELAEQFSGVQETFAEASDAVGFDLWHIAQSGEGLDQTENTQPVLLTASI
ALWRVWLDLGGLAPKYMAGHSLGEYSALVAAGALSLGDAAKLVNLRGKLMQSAVPQGVGAMAAILGLPDEKVIELCQAVT
ASGDGSVEAANYNSQGQVVIAGSAALVNEVMTQAKEQSGKAIALPVSVPSHCSLMKPAAEKFAEALEQTAIELPSLPVIQ
NVNAGIATDVTQLRQALTAQLYQSVQWTRTMQYLQDQGIQYVVECGPGTVLSNLAKRLPNIEKAFAIDSKSRMEDALNAV
LVAEGKIA

Sequences:

>Translated_328_residues
MSAKRLDQVAQATKTAFVFPGQGSQKVGMLAELAEQFSGVQETFAEASDAVGFDLWHIAQSGEGLDQTENTQPVLLTASI
ALWRVWLDLGGLAPKYMAGHSLGEYSALVAAGALSLGDAAKLVNLRGKLMQSAVPQGVGAMAAILGLPDEKVIELCQAVT
ASGDGSVEAANYNSQGQVVIAGSAALVNEVMTQAKEQSGKAIALPVSVPSHCSLMKPAAEKFAEALEQTAIELPSLPVIQ
NVNAGIATDVTQLRQALTAQLYQSVQWTRTMQYLQDQGIQYVVECGPGTVLSNLAKRLPNIEKAFAIDSKSRMEDALNAV
LVAEGKIA
>Mature_327_residues
SAKRLDQVAQATKTAFVFPGQGSQKVGMLAELAEQFSGVQETFAEASDAVGFDLWHIAQSGEGLDQTENTQPVLLTASIA
LWRVWLDLGGLAPKYMAGHSLGEYSALVAAGALSLGDAAKLVNLRGKLMQSAVPQGVGAMAAILGLPDEKVIELCQAVTA
SGDGSVEAANYNSQGQVVIAGSAALVNEVMTQAKEQSGKAIALPVSVPSHCSLMKPAAEKFAEALEQTAIELPSLPVIQN
VNAGIATDVTQLRQALTAQLYQSVQWTRTMQYLQDQGIQYVVECGPGTVLSNLAKRLPNIEKAFAIDSKSRMEDALNAVL
VAEGKIA

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=305, Percent_Identity=32.1311475409836, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI1787334, Length=308, Percent_Identity=50.6493506493506, Blast_Score=295, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17550940, Length=298, Percent_Identity=24.8322147651007, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71984332, Length=294, Percent_Identity=28.9115646258503, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24665753, Length=293, Percent_Identity=33.1058020477816, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34453; Mature: 34322

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKRLDQVAQATKTAFVFPGQGSQKVGMLAELAEQFSGVQETFAEASDAVGFDLWHIAQ
CCHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGEGLDQTENTQPVLLTASIALWRVWLDLGGLAPKYMAGHSLGEYSALVAAGALSLGDAA
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCHHH
KLVNLRGKLMQSAVPQGVGAMAAILGLPDEKVIELCQAVTASGDGSVEAANYNSQGQVVI
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEE
AGSAALVNEVMTQAKEQSGKAIALPVSVPSHCSLMKPAAEKFAEALEQTAIELPSLPVIQ
ECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NVNAGIATDVTQLRQALTAQLYQSVQWTRTMQYLQDQGIQYVVECGPGTVLSNLAKRLPN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCC
IEKAFAIDSKSRMEDALNAVLVAEGKIA
HHHHHCCCCHHHHHHHHHEEEEECCCCC
>Mature Secondary Structure 
SAKRLDQVAQATKTAFVFPGQGSQKVGMLAELAEQFSGVQETFAEASDAVGFDLWHIAQ
CHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SGEGLDQTENTQPVLLTASIALWRVWLDLGGLAPKYMAGHSLGEYSALVAAGALSLGDAA
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHCHHH
KLVNLRGKLMQSAVPQGVGAMAAILGLPDEKVIELCQAVTASGDGSVEAANYNSQGQVVI
HHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEECCCCCCCCEEE
AGSAALVNEVMTQAKEQSGKAIALPVSVPSHCSLMKPAAEKFAEALEQTAIELPSLPVIQ
ECCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHH
NVNAGIATDVTQLRQALTAQLYQSVQWTRTMQYLQDQGIQYVVECGPGTVLSNLAKRLPN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHCCC
IEKAFAIDSKSRMEDALNAVLVAEGKIA
HHHHHCCCCHHHHHHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]