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The map label for this gene is coaX

Identifier: 50084053

GI number: 50084053

Start: 827888

End: 828619

Strand: Reverse

Name: coaX

Synonym: ACIAD0840

Alternate gene names: 50084053

Gene position: 828619-827888 (Counterclockwise)

Preceding gene: 50084054

Following gene: 50084051

Centisome position: 23.03

GC content: 43.44

Gene sequence:

>732_bases
ATGAAGCAATTATGGCTCGATATTGGCAATACACGGCTAAAATACTGGATTACCCAAAATGAAACGGTGATTGAACACGC
TGCCGAACTGCATTTGCAATCGCCATCCGATTTACTTTTGGGCTTAATTCAGCATTTTAATCATCAAAATATTCAAAAAG
TGGGCGTCTCTTCGGTTCTGGATCAACACAATAATGACCGTATTCGCAGCATCCTAAAACGGCTTCATATTCCGATGATC
ATGGCAAAGGTACATCAGGAATATGCTGCTCTTCGCTGTGGTTATGATCATCCCGAACAGCTCGGGATTGATCGGTGGCT
TCAGGTACTTGCTGTTGCACAGCCTGATCGAAATGTATGTGTGATCGGATGTGGTACAGCGCTGACCATCGATCTGGTCA
AAGGTTATCAGCATTTAGGTGGTTACATTCTGCCAAATCTATATTTGCAACGTGATGCGCTGATTCAAAACACCAAAGGC
ATTAAAATTCCAGATTCTGCATTTGATGATCTGGAACCTGGGCACAACACCATTGATGCTGTACATCATGGTATTTTGCT
TGGCTTGGTGAGCACGATTCAAACCATCATGCAGCAGTCTCCCCAGCAGCTCGTATTGACGGGCGGAGATGCACCGTTGT
TTGCCAAATTTTTACAACCTTATCATCCCCAAATTGAACCTGATTTATTACTAAAGGGCTTGCAGCATTATGTAAGGCAT
CAATTACCCTAG

Upstream 100 bases:

>100_bases
TAATCATGAGGGTGCAGTGCTAATCCGAACGCCAGAACAATTGCATCATTTTTATCAAGGCCGTATGCGCCGTATCGAAA
ACACTTCAGGATAAATCAAT

Downstream 100 bases:

>100_bases
TAAAGATTCTAATATCCACGAAAAAGGCGCATCAAGCGCCTTTTTGAGTTTAACTGATGAGTTCAGCTTACTTTTTGTCG
TCTTTACCACCGCCAAACAA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MKQLWLDIGNTRLKYWITQNETVIEHAAELHLQSPSDLLLGLIQHFNHQNIQKVGVSSVLDQHNNDRIRSILKRLHIPMI
MAKVHQEYAALRCGYDHPEQLGIDRWLQVLAVAQPDRNVCVIGCGTALTIDLVKGYQHLGGYILPNLYLQRDALIQNTKG
IKIPDSAFDDLEPGHNTIDAVHHGILLGLVSTIQTIMQQSPQQLVLTGGDAPLFAKFLQPYHPQIEPDLLLKGLQHYVRH
QLP

Sequences:

>Translated_243_residues
MKQLWLDIGNTRLKYWITQNETVIEHAAELHLQSPSDLLLGLIQHFNHQNIQKVGVSSVLDQHNNDRIRSILKRLHIPMI
MAKVHQEYAALRCGYDHPEQLGIDRWLQVLAVAQPDRNVCVIGCGTALTIDLVKGYQHLGGYILPNLYLQRDALIQNTKG
IKIPDSAFDDLEPGHNTIDAVHHGILLGLVSTIQTIMQQSPQQLVLTGGDAPLFAKFLQPYHPQIEPDLLLKGLQHYVRH
QLP
>Mature_243_residues
MKQLWLDIGNTRLKYWITQNETVIEHAAELHLQSPSDLLLGLIQHFNHQNIQKVGVSSVLDQHNNDRIRSILKRLHIPMI
MAKVHQEYAALRCGYDHPEQLGIDRWLQVLAVAQPDRNVCVIGCGTALTIDLVKGYQHLGGYILPNLYLQRDALIQNTKG
IKIPDSAFDDLEPGHNTIDAVHHGILLGLVSTIQTIMQQSPQQLVLTGGDAPLFAKFLQPYHPQIEPDLLLKGLQHYVRH
QLP

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_ACIAD (Q6FDW7)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045563.1
- ProteinModelPortal:   Q6FDW7
- STRING:   Q6FDW7
- GeneID:   2881086
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0840
- NMPDR:   fig|62977.3.peg.753
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   SIYLQRE
- ProtClustDB:   PRK13322
- BioCyc:   ASP62977:ACIAD0840-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 27470; Mature: 27470

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: ACT_SITE 104-104 BINDING 95-95 BINDING 126-126 BINDING 177-177

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLWLDIGNTRLKYWITQNETVIEHAAELHLQSPSDLLLGLIQHFNHQNIQKVGVSSVL
CCCEEEECCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
DQHNNDRIRSILKRLHIPMIMAKVHQEYAALRCGYDHPEQLGIDRWLQVLAVAQPDRNVC
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCCCCEE
VIGCGTALTIDLVKGYQHLGGYILPNLYLQRDALIQNTKGIKIPDSAFDDLEPGHNTIDA
EEECCHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
VHHGILLGLVSTIQTIMQQSPQQLVLTGGDAPLFAKFLQPYHPQIEPDLLLKGLQHYVRH
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QLP
CCC
>Mature Secondary Structure
MKQLWLDIGNTRLKYWITQNETVIEHAAELHLQSPSDLLLGLIQHFNHQNIQKVGVSSVL
CCCEEEECCCCEEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHH
DQHNNDRIRSILKRLHIPMIMAKVHQEYAALRCGYDHPEQLGIDRWLQVLAVAQPDRNVC
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCHHHHHHHHHHCCCCCCEE
VIGCGTALTIDLVKGYQHLGGYILPNLYLQRDALIQNTKGIKIPDSAFDDLEPGHNTIDA
EEECCHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHH
VHHGILLGLVSTIQTIMQQSPQQLVLTGGDAPLFAKFLQPYHPQIEPDLLLKGLQHYVRH
HHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
QLP
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA