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The map label for this gene is alsR [H]

Identifier: 50084027

GI number: 50084027

Start: 804477

End: 805400

Strand: Direct

Name: alsR [H]

Synonym: ACIAD0813

Alternate gene names: 50084027

Gene position: 804477-805400 (Clockwise)

Preceding gene: 50084023

Following gene: 50084029

Centisome position: 22.36

GC content: 40.58

Gene sequence:

>924_bases
ATGATTGATATTCACAAATTGAATGCGTTTGTTGCAGTGGTTGAGGAAAGCAACATTTCCAGAGCTGCAAATCGTTTGCA
TATGCAACAGCCACCTTTGACACGTTTAATCCAGAGTCTTGAGCAAGACCTGAATACGACCTTGCTCAAACGTTTGCCAC
GTGGTGTTGAGGTGACAGAGGCTGGTAAAGTGCTTTATCAGGAAGCTGTAACCATCTTGGCTCATGCCAGTTCTATCCCA
CAAAGAGTACAAAATATTGCGCAAGGCAAAGAAGGCCAGATTAATATTGGATTCACTCACTCTATTGGTTTACATCCTTT
TTTACCGACATTACTGCGTCACTTTAGAGAAAAATTTCCAGCAGTTTCGATTCATCTTGAAGAAGACAGCAGCAGTGCTT
TAACGGATGCGGTGATTAATGAAAAACTCGATATCGTATTTCTACGCAAGCCAGCACCCAAGCATACTGCCGTGCAAACC
ATGCATGTGCTCAATGAGACTTTAATTGTTGCGCTACCAAGTAATCATCCTTTAGCAATGCAACAGGGCGCAATTCATTT
ACCCGATTTAGAACCTTATGAGTTTGTACTTTATCGCCGTTTAGCGGGACAAGACTTATTTGATAATATTCTGGCAAATT
GCTATCAGGCGGGCTTTAGTCCTAACATTGTACAAGAAGCACCCCGATTAACGTCGAGTCTAAATTTAATTGCAGCGGGA
ATTGGGCTTTCAATTGTTCCCGCGTCTATCCAAGACTTTTGGAATAAACAAATTATTTACCGTCCTTTGGAAGCAAAGAA
ACCTTGCATTGCACCGATTTATGCAATTTATAGCGCCAAAGATAATAATATCCGTGTGGCGCATTTTTTAAATCTATTGA
AAGCCAGCCAATCATCTGGAAATGTATTTCATATTAATGAGTAA

Upstream 100 bases:

>100_bases
TAATTACCTCATCTTCAAACGATATATGCATAGCATGAGCCGATCATGGTATATTTACAAATGCTATTTTTGGCAATAAA
CATACTAAAAAAGTATCGTT

Downstream 100 bases:

>100_bases
ACTGGTAGAAATTTAAAATTGGGCCAACCAAATGTTGTTGTGATTTATCTAACGTGACTTTGATTTCTCGGAAGTTAAAG
TCACCATCATCATGATATTT

Product: transcriptional regulator

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MIDIHKLNAFVAVVEESNISRAANRLHMQQPPLTRLIQSLEQDLNTTLLKRLPRGVEVTEAGKVLYQEAVTILAHASSIP
QRVQNIAQGKEGQINIGFTHSIGLHPFLPTLLRHFREKFPAVSIHLEEDSSSALTDAVINEKLDIVFLRKPAPKHTAVQT
MHVLNETLIVALPSNHPLAMQQGAIHLPDLEPYEFVLYRRLAGQDLFDNILANCYQAGFSPNIVQEAPRLTSSLNLIAAG
IGLSIVPASIQDFWNKQIIYRPLEAKKPCIAPIYAIYSAKDNNIRVAHFLNLLKASQSSGNVFHINE

Sequences:

>Translated_307_residues
MIDIHKLNAFVAVVEESNISRAANRLHMQQPPLTRLIQSLEQDLNTTLLKRLPRGVEVTEAGKVLYQEAVTILAHASSIP
QRVQNIAQGKEGQINIGFTHSIGLHPFLPTLLRHFREKFPAVSIHLEEDSSSALTDAVINEKLDIVFLRKPAPKHTAVQT
MHVLNETLIVALPSNHPLAMQQGAIHLPDLEPYEFVLYRRLAGQDLFDNILANCYQAGFSPNIVQEAPRLTSSLNLIAAG
IGLSIVPASIQDFWNKQIIYRPLEAKKPCIAPIYAIYSAKDNNIRVAHFLNLLKASQSSGNVFHINE
>Mature_307_residues
MIDIHKLNAFVAVVEESNISRAANRLHMQQPPLTRLIQSLEQDLNTTLLKRLPRGVEVTEAGKVLYQEAVTILAHASSIP
QRVQNIAQGKEGQINIGFTHSIGLHPFLPTLLRHFREKFPAVSIHLEEDSSSALTDAVINEKLDIVFLRKPAPKHTAVQT
MHVLNETLIVALPSNHPLAMQQGAIHLPDLEPYEFVLYRRLAGQDLFDNILANCYQAGFSPNIVQEAPRLTSSLNLIAAG
IGLSIVPASIQDFWNKQIIYRPLEAKKPCIAPIYAIYSAKDNNIRVAHFLNLLKASQSSGNVFHINE

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=299, Percent_Identity=30.7692307692308, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1788887, Length=279, Percent_Identity=30.8243727598566, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI2367136, Length=278, Percent_Identity=29.136690647482, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788297, Length=260, Percent_Identity=28.4615384615385, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI157672245, Length=254, Percent_Identity=29.1338582677165, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790399, Length=277, Percent_Identity=26.7148014440433, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693105, Length=246, Percent_Identity=25.2032520325203, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=33.5570469798658, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788748, Length=252, Percent_Identity=24.6031746031746, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789506, Length=298, Percent_Identity=23.489932885906, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788481, Length=211, Percent_Identity=25.5924170616114, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787806, Length=254, Percent_Identity=24.0157480314961, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787530, Length=254, Percent_Identity=23.2283464566929, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786508, Length=139, Percent_Identity=25.8992805755396, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790208, Length=251, Percent_Identity=23.9043824701195, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786713, Length=275, Percent_Identity=23.6363636363636, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786401, Length=141, Percent_Identity=29.0780141843972, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082184, Length=256, Percent_Identity=23.046875, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789440, Length=121, Percent_Identity=33.8842975206612, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1789204, Length=276, Percent_Identity=22.1014492753623, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34156; Mature: 34156

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIHKLNAFVAVVEESNISRAANRLHMQQPPLTRLIQSLEQDLNTTLLKRLPRGVEVTE
CCCHHHHCEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AGKVLYQEAVTILAHASSIPQRVQNIAQGKEGQINIGFTHSIGLHPFLPTLLRHFREKFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCC
AVSIHLEEDSSSALTDAVINEKLDIVFLRKPAPKHTAVQTMHVLNETLIVALPSNHPLAM
EEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHH
QQGAIHLPDLEPYEFVLYRRLAGQDLFDNILANCYQAGFSPNIVQEAPRLTSSLNLIAAG
CCCCEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
IGLSIVPASIQDFWNKQIIYRPLEAKKPCIAPIYAIYSAKDNNIRVAHFLNLLKASQSSG
CCCEEECHHHHHHHCCCEEECCCCCCCCCHHHHHHEEECCCCCEEHHHHHHHHHHCCCCC
NVFHINE
CEEEECC
>Mature Secondary Structure
MIDIHKLNAFVAVVEESNISRAANRLHMQQPPLTRLIQSLEQDLNTTLLKRLPRGVEVTE
CCCHHHHCEEEEEEECCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHH
AGKVLYQEAVTILAHASSIPQRVQNIAQGKEGQINIGFTHSIGLHPFLPTLLRHFREKFP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCC
AVSIHLEEDSSSALTDAVINEKLDIVFLRKPAPKHTAVQTMHVLNETLIVALPSNHPLAM
EEEEEEECCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCHH
QQGAIHLPDLEPYEFVLYRRLAGQDLFDNILANCYQAGFSPNIVQEAPRLTSSLNLIAAG
CCCCEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
IGLSIVPASIQDFWNKQIIYRPLEAKKPCIAPIYAIYSAKDNNIRVAHFLNLLKASQSSG
CCCEEECHHHHHHHCCCEEECCCCCCCCCHHHHHHEEECCCCCEEHHHHHHHHHHCCCCC
NVFHINE
CEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]