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The map label for this gene is pilH [H]

Identifier: 50084002

GI number: 50084002

Start: 775620

End: 775991

Strand: Direct

Name: pilH [H]

Synonym: ACIAD0787

Alternate gene names: 50084002

Gene position: 775620-775991 (Clockwise)

Preceding gene: 50084001

Following gene: 50084003

Centisome position: 21.55

GC content: 45.7

Gene sequence:

>372_bases
ATGGCACGTATTTTGATTGTTGATGATTCACCAACGGAAACTTATCGTTTTCGTGACATACTGACCAGACATGGCTACCA
AGTGTTAGAGGCGACCAATGGCGCAGATGGGGTAACACTTGCGCAGGCAGAACAGCCTGATTTGGTGCTTATGGATGTGG
TGATGCCAGGTGTAAATGGTTTTCAGGCAACACGTCAGATTTGTCGGGGTGAGCAAACCAAGCATATACCTGTGGTGATT
GTGAGTACCAAAGACCAAGCGACAGATCGTATCTGGGGTAAACGTCAGGGTGCCCGTGAATATCTCACCAAACCCATTGA
TGAAAATCAGCTGATTGAAGTCATCCAGCAATATATTCATACGGATGATTAA

Upstream 100 bases:

>100_bases
GCTCAGATGAGTATCTGATTAAACCTTTTAGTAAAGATGAATTGCTCACCGCAATTCGTAATCACGTCAGTGTATAACAC
GATATTGTTTTGAGGTCTTT

Downstream 100 bases:

>100_bases
AAGATGAGCTCTGCAACCACATCTGCTGGTTTGGAGCAACTTGATGCTGATCAGCATCATGAGATTGATCAAGATCAGCG
TTGGACAGGCATTGCTTTTG

Product: twitching motility protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 123; Mature: 122

Protein sequence:

>123_residues
MARILIVDDSPTETYRFRDILTRHGYQVLEATNGADGVTLAQAEQPDLVLMDVVMPGVNGFQATRQICRGEQTKHIPVVI
VSTKDQATDRIWGKRQGAREYLTKPIDENQLIEVIQQYIHTDD

Sequences:

>Translated_123_residues
MARILIVDDSPTETYRFRDILTRHGYQVLEATNGADGVTLAQAEQPDLVLMDVVMPGVNGFQATRQICRGEQTKHIPVVI
VSTKDQATDRIWGKRQGAREYLTKPIDENQLIEVIQQYIHTDD
>Mature_122_residues
ARILIVDDSPTETYRFRDILTRHGYQVLEATNGADGVTLAQAEQPDLVLMDVVMPGVNGFQATRQICRGEQTKHIPVVIV
STKDQATDRIWGKRQGAREYLTKPIDENQLIEVIQQYIHTDD

Specific function: May be a part of a signal-transduction system that regulates twitching motility by controlling pilus function (extension and retraction) [H]

COG id: COG0784

COG function: function code T; FOG: CheY-like receiver

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=114, Percent_Identity=32.4561403508772, Blast_Score=72, Evalue=1e-14,
Organism=Escherichia coli, GI1790863, Length=108, Percent_Identity=31.4814814814815, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1787229, Length=109, Percent_Identity=31.1926605504587, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788905, Length=114, Percent_Identity=32.4561403508772, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=110, Percent_Identity=29.0909090909091, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1788394, Length=114, Percent_Identity=30.7017543859649, Blast_Score=62, Evalue=1e-11,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=28.8135593220339, Blast_Score=60, Evalue=4e-11,
Organism=Escherichia coli, GI1788713, Length=129, Percent_Identity=31.7829457364341, Blast_Score=59, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 13937; Mature: 13806

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARILIVDDSPTETYRFRDILTRHGYQVLEATNGADGVTLAQAEQPDLVLMDVVMPGVNG
CEEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCCEEEEEEHHCCCCH
FQATRQICRGEQTKHIPVVIVSTKDQATDRIWGKRQGAREYLTKPIDENQLIEVIQQYIH
HHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHC
TDD
CCC
>Mature Secondary Structure 
ARILIVDDSPTETYRFRDILTRHGYQVLEATNGADGVTLAQAEQPDLVLMDVVMPGVNG
EEEEEEECCCCCHHHHHHHHHHCCEEEEEECCCCCCEEEECCCCCCEEEEEEHHCCCCH
FQATRQICRGEQTKHIPVVIVSTKDQATDRIWGKRQGAREYLTKPIDENQLIEVIQQYIH
HHHHHHHHCCCCCCCCCEEEEECCCCHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHC
TDD
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7908398; 10984043 [H]