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The map label for this gene is mtnN [H]

Identifier: 50083988

GI number: 50083988

Start: 758483

End: 759358

Strand: Direct

Name: mtnN [H]

Synonym: ACIAD0773

Alternate gene names: 50083988

Gene position: 758483-759358 (Clockwise)

Preceding gene: 50083987

Following gene: 50083990

Centisome position: 21.08

GC content: 43.26

Gene sequence:

>876_bases
ATGAAGTTTAAAGCGTTGTTTACTGCACTTGGATTATGCTCAGGTTTGTTTTTGACCGCATGTAGTAGCCATTATGTTGC
ATCTACTCCCTCAGTTGAAGTGAAGTCAGCATTGAAACCGATTATTATTCAGGGTGCTTTACCCGTCGAGTCTGAGCAAA
TGGCATCCAAACTCAGTGATGTCAGTGTAGAAACAATTGGTGGATGGAAATTCTGGAAAGGCACGTATCACGGTTATCCA
GTGATTATCTCTAAAACCCGTATGGGCATGAGTAACTCAGCCGCTGCAACTGCGATTGCGATTGAGCGCTATCAACCTGT
TGCGATTATCAATCAGGGCACATCGGGCGGACATGATCCGAAGCTCAATGTGTACGACATTGTGCTTGGCCAATACACCA
CGAATATTGGTGCATTTAAAACGCCTCATCGTCCAGTAGGCGGCGGTTCAGATGCATTGACATGGAACGAAGCTTTTGAT
GTATTACCAAAAGATGAATCTGATCCAGAACCAATCGCAATTCGTAAATTTACAGCAGATCAGGGCTTAATGGCTGCTGC
TCAGCGTGTAAAATCGACTTACAGCAAAGGCAAAGTGGTAGAAGGTACGATTGGTTCAGCAGATGTTTGGAATAACGAAC
TTGACCGTATCAAATTCTTCAACACACGTTATGGTACATCTGTAGAAGAGATGGAAGCGGCATCGGTTGCACAAATCGCT
AGCCAGTTTAATGTTCCATTTATTGGCATTCGCGTGGTGTCAAACAACATCACGAATAATGGCAAGTATGATGGCGGTAC
AGGTGAAGCGTGTCAGGAATATGTTTTACATGTCGCTGAAGATTACATGAAAAATCTGAAAGCAAAAACCAATTAA

Upstream 100 bases:

>100_bases
TCATGCTATCTATCTGATTATTTAAATTTTATTGATTAGTTTTTTTGAACGATTGGCATAAAATTTGCTAATTATTTGTT
TTTGAATTTAAGGATAACGA

Downstream 100 bases:

>100_bases
TTACTTAAGGTCGAACTGCGGTTCGGCCTTTTTTTGACGTCTTTTTTGACGGTGTCGCATGATACTCCAGCGCCAGAAAA
TTTCTGTGGCTGCATATAGG

Product: MTA/SAH nucleosidase

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MKFKALFTALGLCSGLFLTACSSHYVASTPSVEVKSALKPIIIQGALPVESEQMASKLSDVSVETIGGWKFWKGTYHGYP
VIISKTRMGMSNSAAATAIAIERYQPVAIINQGTSGGHDPKLNVYDIVLGQYTTNIGAFKTPHRPVGGGSDALTWNEAFD
VLPKDESDPEPIAIRKFTADQGLMAAAQRVKSTYSKGKVVEGTIGSADVWNNELDRIKFFNTRYGTSVEEMEAASVAQIA
SQFNVPFIGIRVVSNNITNNGKYDGGTGEACQEYVLHVAEDYMKNLKAKTN

Sequences:

>Translated_291_residues
MKFKALFTALGLCSGLFLTACSSHYVASTPSVEVKSALKPIIIQGALPVESEQMASKLSDVSVETIGGWKFWKGTYHGYP
VIISKTRMGMSNSAAATAIAIERYQPVAIINQGTSGGHDPKLNVYDIVLGQYTTNIGAFKTPHRPVGGGSDALTWNEAFD
VLPKDESDPEPIAIRKFTADQGLMAAAQRVKSTYSKGKVVEGTIGSADVWNNELDRIKFFNTRYGTSVEEMEAASVAQIA
SQFNVPFIGIRVVSNNITNNGKYDGGTGEACQEYVLHVAEDYMKNLKAKTN
>Mature_291_residues
MKFKALFTALGLCSGLFLTACSSHYVASTPSVEVKSALKPIIIQGALPVESEQMASKLSDVSVETIGGWKFWKGTYHGYP
VIISKTRMGMSNSAAATAIAIERYQPVAIINQGTSGGHDPKLNVYDIVLGQYTTNIGAFKTPHRPVGGGSDALTWNEAFD
VLPKDESDPEPIAIRKFTADQGLMAAAQRVKSTYSKGKVVEGTIGSADVWNNELDRIKFFNTRYGTSVEEMEAASVAQIA
SQFNVPFIGIRVVSNNITNNGKYDGGTGEACQEYVLHVAEDYMKNLKAKTN

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 31432; Mature: 31432

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00237 G_PROTEIN_RECEP_F1_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFKALFTALGLCSGLFLTACSSHYVASTPSVEVKSALKPIIIQGALPVESEQMASKLSD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHH
VSVETIGGWKFWKGTYHGYPVIISKTRMGMSNSAAATAIAIERYQPVAIINQGTSGGHDP
CCEEEECCEEEECCCCCCCEEEEEECCCCCCCCCHHHEEEHCCCCCEEEEECCCCCCCCC
KLNVYDIVLGQYTTNIGAFKTPHRPVGGGSDALTWNEAFDVLPKDESDPEPIAIRKFTAD
CCEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCCCCCCEEEEEECCC
QGLMAAAQRVKSTYSKGKVVEGTIGSADVWNNELDRIKFFNTRYGTSVEEMEAASVAQIA
CHHHHHHHHHHHHHHCCCEEECCCCCCHHCCCCHHHEEEECCCCCCCHHHHHHHHHHHHH
SQFNVPFIGIRVVSNNITNNGKYDGGTGEACQEYVLHVAEDYMKNLKAKTN
HHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MKFKALFTALGLCSGLFLTACSSHYVASTPSVEVKSALKPIIIQGALPVESEQMASKLSD
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEECCCCCCHHHHHHHHHH
VSVETIGGWKFWKGTYHGYPVIISKTRMGMSNSAAATAIAIERYQPVAIINQGTSGGHDP
CCEEEECCEEEECCCCCCCEEEEEECCCCCCCCCHHHEEEHCCCCCEEEEECCCCCCCCC
KLNVYDIVLGQYTTNIGAFKTPHRPVGGGSDALTWNEAFDVLPKDESDPEPIAIRKFTAD
CCEEEEEEEEHHHCCCCCCCCCCCCCCCCCCCEEHHHHHCCCCCCCCCCCCEEEEEECCC
QGLMAAAQRVKSTYSKGKVVEGTIGSADVWNNELDRIKFFNTRYGTSVEEMEAASVAQIA
CHHHHHHHHHHHHHHCCCEEECCCCCCHHCCCCHHHEEEECCCCCCCHHHHHHHHHHHHH
SQFNVPFIGIRVVSNNITNNGKYDGGTGEACQEYVLHVAEDYMKNLKAKTN
HHCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA