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The map label for this gene is tsx [H]

Identifier: 50083985

GI number: 50083985

Start: 754824

End: 755669

Strand: Reverse

Name: tsx [H]

Synonym: ACIAD0769

Alternate gene names: 50083985

Gene position: 755669-754824 (Counterclockwise)

Preceding gene: 50083989

Following gene: 50083984

Centisome position: 21.0

GC content: 41.84

Gene sequence:

>846_bases
ATGTCTCTTAAATCGTTAAGCACTGTTTTTTTAGCTGCAACCACTTTGCTGGGTGTACAACAGGCCAATGCCGATGTGAA
TGCTACACTTTGGGGTATTTATAGCAATAACATCAAATTTTCTCCAAAAACGGTAGAAAATGCTTATCTTGAGCTTGAAT
ATTATGGTCAAACTGGGCCAATCGATTGGTATGGTTATTTTGATGCGCCAAAATATTTTGGTGGTAATGACAACATCAAA
GGCGTTTGGGACAAAGACGGTTCTAAACTATTTGCTGAAAACCAGCCAAAAGTTTCGTTCAATCGTTTAACGGGTAAAGA
TCTCTCTGTTGGGCCATTTAAAGACTGGTTCTTTGCAACTGACTGGATCGTAGACGCTGGTGGTCACTCGAATAACAGCC
AAAATACCTTGTACTATGGTTTGGGTACCTCAATTGACACCCACACCAAACTTGGTATGAATGTAAACGTGTTTGCAAAA
CAGCAATGGGAAAACTACGGCGCGCCAAACTCATATACCTCAGATGATGGCGGACGTTTACAGGTTCAGTTTTTCTACCC
GCTTTATTCATTTAATAATGGCGCATCGCTCAACTATTTCACCTTTACCAACTATGACTTTGGTTCAAAACTTGGCGATA
AAGACCCGAACCGTACCAATGAAGCTTTGGTTTCAACGCATGTTTTTTCTTATAACATGAAGCATCTGCGTTTATTCACT
GCTGCACGTTATTTCCATAATGGCGGTCAGTTTAAAGACGGCGCGATTGCCAACTGGGGCAACGGTGACTTTGTGCAAAA
TAGCAATGGTTGGGGCTACTACGTCGCTGCGGGTTACCAGTTCTAA

Upstream 100 bases:

>100_bases
CATTGCTTAGCTTTGCTTGCGTTCGTTTTTTCTAAAGAATTAACTGATTTGGCATCTTCCGATATGCCTCGAATTTTATG
ATGTTGGAGTAGTTCTAATA

Downstream 100 bases:

>100_bases
GTATTTCATCTCTTGATTTATCTCCCTCAAGCCTGCTCGCAGGCTTGAGTTGTTTTAAGCGTTTCATCTAAGTGCTCTTT
TTTAATTTTCCCTTCTCTGT

Product: nucleoside-specific channel-forming protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MSLKSLSTVFLAATTLLGVQQANADVNATLWGIYSNNIKFSPKTVENAYLELEYYGQTGPIDWYGYFDAPKYFGGNDNIK
GVWDKDGSKLFAENQPKVSFNRLTGKDLSVGPFKDWFFATDWIVDAGGHSNNSQNTLYYGLGTSIDTHTKLGMNVNVFAK
QQWENYGAPNSYTSDDGGRLQVQFFYPLYSFNNGASLNYFTFTNYDFGSKLGDKDPNRTNEALVSTHVFSYNMKHLRLFT
AARYFHNGGQFKDGAIANWGNGDFVQNSNGWGYYVAAGYQF

Sequences:

>Translated_281_residues
MSLKSLSTVFLAATTLLGVQQANADVNATLWGIYSNNIKFSPKTVENAYLELEYYGQTGPIDWYGYFDAPKYFGGNDNIK
GVWDKDGSKLFAENQPKVSFNRLTGKDLSVGPFKDWFFATDWIVDAGGHSNNSQNTLYYGLGTSIDTHTKLGMNVNVFAK
QQWENYGAPNSYTSDDGGRLQVQFFYPLYSFNNGASLNYFTFTNYDFGSKLGDKDPNRTNEALVSTHVFSYNMKHLRLFT
AARYFHNGGQFKDGAIANWGNGDFVQNSNGWGYYVAAGYQF
>Mature_280_residues
SLKSLSTVFLAATTLLGVQQANADVNATLWGIYSNNIKFSPKTVENAYLELEYYGQTGPIDWYGYFDAPKYFGGNDNIKG
VWDKDGSKLFAENQPKVSFNRLTGKDLSVGPFKDWFFATDWIVDAGGHSNNSQNTLYYGLGTSIDTHTKLGMNVNVFAKQ
QWENYGAPNSYTSDDGGRLQVQFFYPLYSFNNGASLNYFTFTNYDFGSKLGDKDPNRTNEALVSTHVFSYNMKHLRLFTA
ARYFHNGGQFKDGAIANWGNGDFVQNSNGWGYYVAAGYQF

Specific function: Constitutes the receptor for colicin K and phage T6, and functions as substrate-specific channel for nucleosides and deoxynucleosides [H]

COG id: COG3248

COG function: function code M; Nucleoside-binding outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786612, Length=254, Percent_Identity=43.7007874015748, Blast_Score=207, Evalue=6e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003055
- InterPro:   IPR018013 [H]

Pfam domain/function: PF03502 Channel_Tsx [H]

EC number: NA

Molecular weight: Translated: 31539; Mature: 31408

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKSLSTVFLAATTLLGVQQANADVNATLWGIYSNNIKFSPKTVENAYLELEYYGQTGP
CCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEECCCCCCCEEEEEEEECCCCC
IDWYGYFDAPKYFGGNDNIKGVWDKDGSKLFAENQPKVSFNRLTGKDLSVGPFKDWFFAT
EEEEEEECCCCEECCCCCCCEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCHHEEEE
DWIVDAGGHSNNSQNTLYYGLGTSIDTHTKLGMNVNVFAKQQWENYGAPNSYTSDDGGRL
EEEEECCCCCCCCCCEEEEECCCCCCCCEECCCEEEEEEEEHHHCCCCCCCCCCCCCCEE
QVQFFYPLYSFNNGASLNYFTFTNYDFGSKLGDKDPNRTNEALVSTHVFSYNMKHLRLFT
EEEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHEEEEEEEEECCHHHEEEH
AARYFHNGGQFKDGAIANWGNGDFVQNSNGWGYYVAAGYQF
HHHHHHCCCCCCCCCEEECCCCCEEECCCCCEEEEEEECCC
>Mature Secondary Structure 
SLKSLSTVFLAATTLLGVQQANADVNATLWGIYSNNIKFSPKTVENAYLELEYYGQTGP
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCEEECCCCCCCEEEEEEEECCCCC
IDWYGYFDAPKYFGGNDNIKGVWDKDGSKLFAENQPKVSFNRLTGKDLSVGPFKDWFFAT
EEEEEEECCCCEECCCCCCCEEECCCCCEEEECCCCCEEEEEECCCCCCCCCCCHHEEEE
DWIVDAGGHSNNSQNTLYYGLGTSIDTHTKLGMNVNVFAKQQWENYGAPNSYTSDDGGRL
EEEEECCCCCCCCCCEEEEECCCCCCCCEECCCEEEEEEEEHHHCCCCCCCCCCCCCCEE
QVQFFYPLYSFNNGASLNYFTFTNYDFGSKLGDKDPNRTNEALVSTHVFSYNMKHLRLFT
EEEEEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCHHEEEEEEEEECCHHHEEEH
AARYFHNGGQFKDGAIANWGNGDFVQNSNGWGYYVAAGYQF
HHHHHHCCCCCCCCCEEECCCCCEEECCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]