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The map label for this gene is rhtC [H]

Identifier: 50083976

GI number: 50083976

Start: 744567

End: 745190

Strand: Direct

Name: rhtC [H]

Synonym: ACIAD0759

Alternate gene names: 50083976

Gene position: 744567-745190 (Clockwise)

Preceding gene: 50083975

Following gene: 50083977

Centisome position: 20.69

GC content: 40.06

Gene sequence:

>624_bases
TTGGATAGCTTAATTCCGCTCTTTTCGATTGCTGCTGCATTGATGCTAGGCGCAATGAGTCCTGGTCCAAGTTTTATCTA
TGTTGCTCAAAACTCAATCGCCAAATCGCGTAAACACGGTTTATTTACAGCATTGGGAACAGGTACAGGTGCTGCAATCT
TCGGTTTTTTAGCAGTTATGGGATTACAGGCTGTTTTGCTGGCCGTTCCTTCAGCCTATATGATTTTGAAAATTGGGGGC
GGTCTATACTTGCTGTGGATGTCATTTAAAATTTTGAAATATGCCAAGCAGCCAATGGAAACAGGAAGCGCTGTTGCGAC
GCAGATGACGTATTCTAGTGCATATCGCTATGGCCTATTGACTCAGCTTAGTAATCCTAAAATTGCAATTGTTTTGGCAA
GTGTTTTTACGGCTTTGTTACCTAAAGAGATTCCAGGCTATTATTATATTGCTTTGCCTGTAATCTGTTTTATGATTGAT
GCTGGATGGTATTCACTGGTTGCATTACTGCTTTCTTCTGAAAAGCCAAGAACTTTTTACATTAAAGCTAAAACCATGAT
TGACCGTGTGACGGGTGGCATTGTCACAATTTTAGGTTTAAAGCTAATTTTTTCTAGCCGTTAA

Upstream 100 bases:

>100_bases
GATGATGGTTCATTTCGAAGCGAGGTGATGTATTTGGTACTCAGCAAATCTTCTTGAACCTGTTAGAATGTATACCTGTT
TTTTGATTGAGATATAAATC

Downstream 100 bases:

>100_bases
TTCTGACGATACCAAATTCTACACTATAAAAAGTATGGATTTTATCTGTACTTTTTTATTTAATATAAATTGAAATAGAT
TAAAGGATGCATCTGAGCAT

Product: threonine efflux protein (RhtC)

Products: Proton [Cytoplasm]; L-threonine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MDSLIPLFSIAAALMLGAMSPGPSFIYVAQNSIAKSRKHGLFTALGTGTGAAIFGFLAVMGLQAVLLAVPSAYMILKIGG
GLYLLWMSFKILKYAKQPMETGSAVATQMTYSSAYRYGLLTQLSNPKIAIVLASVFTALLPKEIPGYYYIALPVICFMID
AGWYSLVALLLSSEKPRTFYIKAKTMIDRVTGGIVTILGLKLIFSSR

Sequences:

>Translated_207_residues
MDSLIPLFSIAAALMLGAMSPGPSFIYVAQNSIAKSRKHGLFTALGTGTGAAIFGFLAVMGLQAVLLAVPSAYMILKIGG
GLYLLWMSFKILKYAKQPMETGSAVATQMTYSSAYRYGLLTQLSNPKIAIVLASVFTALLPKEIPGYYYIALPVICFMID
AGWYSLVALLLSSEKPRTFYIKAKTMIDRVTGGIVTILGLKLIFSSR
>Mature_207_residues
MDSLIPLFSIAAALMLGAMSPGPSFIYVAQNSIAKSRKHGLFTALGTGTGAAIFGFLAVMGLQAVLLAVPSAYMILKIGG
GLYLLWMSFKILKYAKQPMETGSAVATQMTYSSAYRYGLLTQLSNPKIAIVLASVFTALLPKEIPGYYYIALPVICFMID
AGWYSLVALLLSSEKPRTFYIKAKTMIDRVTGGIVTILGLKLIFSSR

Specific function: Conducts the efflux of threonine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994978, Length=205, Percent_Identity=29.2682926829268, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1786522, Length=205, Percent_Identity=24.8780487804878, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788099, Length=178, Percent_Identity=25.2808988764045, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22300; Mature: 22300

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLIPLFSIAAALMLGAMSPGPSFIYVAQNSIAKSRKHGLFTALGTGTGAAIFGFLAVM
CCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCEEEECCCCHHHHHHHHHHH
GLQAVLLAVPSAYMILKIGGGLYLLWMSFKILKYAKQPMETGSAVATQMTYSSAYRYGLL
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TQLSNPKIAIVLASVFTALLPKEIPGYYYIALPVICFMIDAGWYSLVALLLSSEKPRTFY
HHCCCCCCEEHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEE
IKAKTMIDRVTGGIVTILGLKLIFSSR
EEHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDSLIPLFSIAAALMLGAMSPGPSFIYVAQNSIAKSRKHGLFTALGTGTGAAIFGFLAVM
CCCCHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCEEEECCCCHHHHHHHHHHH
GLQAVLLAVPSAYMILKIGGGLYLLWMSFKILKYAKQPMETGSAVATQMTYSSAYRYGLL
HHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
TQLSNPKIAIVLASVFTALLPKEIPGYYYIALPVICFMIDAGWYSLVALLLSSEKPRTFY
HHCCCCCCEEHHHHHHHHHHHHHCCCEEHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEE
IKAKTMIDRVTGGIVTILGLKLIFSSR
EEHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-threonine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + L-threonine [Cytoplasm] = Proton [Cytoplasm] + L-threonine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]