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The map label for this gene is rstA [H]

Identifier: 50083946

GI number: 50083946

Start: 710825

End: 711541

Strand: Direct

Name: rstA [H]

Synonym: ACIAD0726

Alternate gene names: 50083946

Gene position: 710825-711541 (Clockwise)

Preceding gene: 50083943

Following gene: 50083947

Centisome position: 19.75

GC content: 43.1

Gene sequence:

>717_bases
ATGAGCCAAGAAGAAAAGTTACCCAAGATTTTAATTGTTGAAGATGATGAGCGTCTGGCACGTCTGACACAAGAATATTT
AATCCGTAACGGATTGGAAGTGGGTGTTGAAACTGACGGTAATCGCGCCATTCGTCGCATTATTAGTGAACAGCCTGATT
TGGTCGTACTTGATGTGATGTTGCCAGGTGCAGACGGCTTAACGGTTTGTCGTGAAGTGCGTCCACATTATCATCAGCCG
ATTTTGATGCTTACAGCCAGAACTGAAGATATGGATCAGGTTTTGGGTCTGGAAATGGGTGCAGATGACTATGTTGCTAA
ACCTGTTCAGCCACGTGTATTACTGGCACGAATTCGTGCTTTGTTGCGTCGTACAGACAAGACTGTTGAGGATGAAGTTG
CTCAACGTATCGAATTTGATGATTTAGTCATTGATAATGGTGGTCGTTCGGTAACTTTAAATGGCGAGCTGGTCGATTTT
ACCAGTGCCGAATATGATTTATTGTGGTTACTCGCTTCAAACGCGGGCCGGATCCTATCGCGTGAAGATATTTTTGAGCG
TCTTCGTGGCATTGAATATGATGGTCAAGATCGTTCGATTGACGTTCGTATTTCACGTATTCGTCCAAAAATTGGTGATG
ATCCTGAAAATCCAAAACGTATCAAAACTGTGCGCAGTAAAGGTTACTTGTTTGTGAAGGAAACCAATGGCTTGTAA

Upstream 100 bases:

>100_bases
ACTTGTTTACAATGTAAACGTGTGTATATTGCAATCTATTAAGTCAGTGTATCTGCTGGATTTTGATAGATACACTCCAA
TAGATCATAGGGGCAAAAGT

Downstream 100 bases:

>100_bases
AAGCAAGTAATGGTGATGAGTAAAACTTCCATTTAAGGCTGATCGAGTGTTTAAACACAGTATTTTTTTGCGCATTTATG
CAGGCTTGGTCGTTCTGGTC

Product: two-component regulatory system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSQEEKLPKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVMLPGADGLTVCREVRPHYHQP
ILMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRALLRRTDKTVEDEVAQRIEFDDLVIDNGGRSVTLNGELVDF
TSAEYDLLWLLASNAGRILSREDIFERLRGIEYDGQDRSIDVRISRIRPKIGDDPENPKRIKTVRSKGYLFVKETNGL

Sequences:

>Translated_238_residues
MSQEEKLPKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVMLPGADGLTVCREVRPHYHQP
ILMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRALLRRTDKTVEDEVAQRIEFDDLVIDNGGRSVTLNGELVDF
TSAEYDLLWLLASNAGRILSREDIFERLRGIEYDGQDRSIDVRISRIRPKIGDDPENPKRIKTVRSKGYLFVKETNGL
>Mature_237_residues
SQEEKLPKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVMLPGADGLTVCREVRPHYHQPI
LMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRALLRRTDKTVEDEVAQRIEFDDLVIDNGGRSVTLNGELVDFT
SAEYDLLWLLASNAGRILSREDIFERLRGIEYDGQDRSIDVRISRIRPKIGDDPENPKRIKTVRSKGYLFVKETNGL

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=231, Percent_Identity=43.7229437229437, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=42.1052631578947, Blast_Score=171, Evalue=5e-44,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=37.6106194690265, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=38.5281385281385, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=36.6071428571429, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=35.1931330472103, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=34.061135371179, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.7142857142857, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1789402, Length=222, Percent_Identity=35.5855855855856, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.0884955752212, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=33.9366515837104, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787229, Length=211, Percent_Identity=34.1232227488152, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790552, Length=234, Percent_Identity=35.8974358974359, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32.4444444444444, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788550, Length=101, Percent_Identity=32.6732673267327, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27136; Mature: 27005

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQEEKLPKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVM
CCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEEEE
LPGADGLTVCREVRPHYHQPILMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRA
ECCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHCCCCCCCCHHCCCCCHHHHHHHHHH
LLRRTDKTVEDEVAQRIEFDDLVIDNGGRSVTLNGELVDFTSAEYDLLWLLASNAGRILS
HHHHHCCCHHHHHHHHCCCCCEEEECCCCEEEECCEEEEECCCCEEEEEEEECCCCCCCC
REDIFERLRGIEYDGQDRSIDVRISRIRPKIGDDPENPKRIKTVRSKGYLFVKETNGL
HHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEEECCCC
>Mature Secondary Structure 
SQEEKLPKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVM
CCCCCCCEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEEEEE
LPGADGLTVCREVRPHYHQPILMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRA
ECCCCHHHHHHHHCCCCCCCEEEEEECCCCHHHHHCCCCCCCCHHCCCCCHHHHHHHHHH
LLRRTDKTVEDEVAQRIEFDDLVIDNGGRSVTLNGELVDFTSAEYDLLWLLASNAGRILS
HHHHHCCCHHHHHHHHCCCCCEEEECCCCEEEECCEEEEECCCCEEEEEEEECCCCCCCC
REDIFERLRGIEYDGQDRSIDVRISRIRPKIGDDPENPKRIKTVRSKGYLFVKETNGL
HHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCHHHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]