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The map label for this gene is dsbC [H]

Identifier: 50083935

GI number: 50083935

Start: 700198

End: 700905

Strand: Reverse

Name: dsbC [H]

Synonym: ACIAD0713

Alternate gene names: 50083935

Gene position: 700905-700198 (Counterclockwise)

Preceding gene: 50083936

Following gene: 50083934

Centisome position: 19.48

GC content: 41.1

Gene sequence:

>708_bases
ATGAAAACTTGGTTAACTACACTTATTTTAAGTCTATCGACTTTGGGGCTGGCACATGCAGATGTTGCGACAACACAGCA
AAACTTAAAGAAAAACTTTCCAGAGATTCCAGTTTCTGCGGTCAATACTACGCCTGTTAAGGGGGTTTATGAAGTCATCA
CTGAAGGCCAAATTGTCTATACCAATGACGATGCACAGTACTTTTTCGTAGGTAATCTGGTCGATCCTAAAAATCAGCGG
AACCTGACAGCCGAACGCATGCAGCAACTCAATAAAATTGATGTCAGCACATTACCCTTAAACCAAGCGATCAAACACGT
CAAAGGTAATGGCAAAAGAACACTGTATATTTTTAGTGACCCTGACTGTCCTTATTGCCAGCGCCTCGAAAAAGAACTTA
CTGCGGTAGATAATGTGACCATCTATTTATTTTTGTTCCCGTTGACGACGTTGCATCCAAATGCAGAAACCATAGCAACT
CAGATCTGGTGTTCAAAAAATCAATATCAGGCATGGCAAGATTATTTACTCAATCATAAAGCACCAACAGCCTCTCAAAA
ATGTAGCACCCCGATCCAAAAAAATCTGGCGTTAGGACAAAAACTCAACATTAATGGCACACCTACCATGTACCTCAAAA
ATGGAGAACGCATTGCGGGTGCTATGCAAGCAGGTCAATTAAATACGTTGCTGGATCAAGCCCAATAA

Upstream 100 bases:

>100_bases
TTAGTTATGCTAAGCGATGAACAACTTCACACATTTTTTTACGAAAGTTGCTTTATATTTTAGGCATTATTCTCACAATA
AAACGATCACTGGAATCATG

Downstream 100 bases:

>100_bases
TCCCATAGCATCACTCATGGGTATAACAACTTCTGAATAATTAACTTTATTAAAAAATCATGATTGAATGTTAATGGTGA
CGTATCTTTCTTCAAAAGCT

Product: thiol:disulfide interchange protein (DsbC-like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MKTWLTTLILSLSTLGLAHADVATTQQNLKKNFPEIPVSAVNTTPVKGVYEVITEGQIVYTNDDAQYFFVGNLVDPKNQR
NLTAERMQQLNKIDVSTLPLNQAIKHVKGNGKRTLYIFSDPDCPYCQRLEKELTAVDNVTIYLFLFPLTTLHPNAETIAT
QIWCSKNQYQAWQDYLLNHKAPTASQKCSTPIQKNLALGQKLNINGTPTMYLKNGERIAGAMQAGQLNTLLDQAQ

Sequences:

>Translated_235_residues
MKTWLTTLILSLSTLGLAHADVATTQQNLKKNFPEIPVSAVNTTPVKGVYEVITEGQIVYTNDDAQYFFVGNLVDPKNQR
NLTAERMQQLNKIDVSTLPLNQAIKHVKGNGKRTLYIFSDPDCPYCQRLEKELTAVDNVTIYLFLFPLTTLHPNAETIAT
QIWCSKNQYQAWQDYLLNHKAPTASQKCSTPIQKNLALGQKLNINGTPTMYLKNGERIAGAMQAGQLNTLLDQAQ
>Mature_235_residues
MKTWLTTLILSLSTLGLAHADVATTQQNLKKNFPEIPVSAVNTTPVKGVYEVITEGQIVYTNDDAQYFFVGNLVDPKNQR
NLTAERMQQLNKIDVSTLPLNQAIKHVKGNGKRTLYIFSDPDCPYCQRLEKELTAVDNVTIYLFLFPLTTLHPNAETIAT
QIWCSKNQYQAWQDYLLNHKAPTASQKCSTPIQKNLALGQKLNINGTPTMYLKNGERIAGAMQAGQLNTLLDQAQ

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=236, Percent_Identity=28.8135593220339, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 26284; Mature: 26284

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTWLTTLILSLSTLGLAHADVATTQQNLKKNFPEIPVSAVNTTPVKGVYEVITEGQIVY
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEE
TNDDAQYFFVGNLVDPKNQRNLTAERMQQLNKIDVSTLPLNQAIKHVKGNGKRTLYIFSD
ECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECC
PDCPYCQRLEKELTAVDNVTIYLFLFPLTTLHPNAETIATQIWCSKNQYQAWQDYLLNHK
CCCHHHHHHHHHHHHHCCEEEEEEEEEHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCC
APTASQKCSTPIQKNLALGQKLNINGTPTMYLKNGERIAGAMQAGQLNTLLDQAQ
CCCCCHHCCCCHHHHHCCCCEECCCCCCEEEEECCCHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKTWLTTLILSLSTLGLAHADVATTQQNLKKNFPEIPVSAVNTTPVKGVYEVITEGQIVY
CHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCEEEE
TNDDAQYFFVGNLVDPKNQRNLTAERMQQLNKIDVSTLPLNQAIKHVKGNGKRTLYIFSD
ECCCCEEEEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCEEEEEECC
PDCPYCQRLEKELTAVDNVTIYLFLFPLTTLHPNAETIATQIWCSKNQYQAWQDYLLNHK
CCCHHHHHHHHHHHHHCCEEEEEEEEEHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCC
APTASQKCSTPIQKNLALGQKLNINGTPTMYLKNGERIAGAMQAGQLNTLLDQAQ
CCCCCHHCCCCHHHHHCCCCEECCCCCCEEEEECCCHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]