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The map label for this gene is omp38 [H]

Identifier: 50083922

GI number: 50083922

Start: 684455

End: 685522

Strand: Direct

Name: omp38 [H]

Synonym: ACIAD0697

Alternate gene names: 50083922

Gene position: 684455-685522 (Clockwise)

Preceding gene: 50083918

Following gene: 50083926

Centisome position: 19.02

GC content: 42.79

Gene sequence:

>1068_bases
ATGAAATTGAGTCGTATTGCACTTGCTACTATGCTTGTTGCTGCTCCACTAGCTGCTGCTAACGCGGGTGTAACAGTAAC
TCCATTATTACTTGGTTACACATTCCAAGATTCACAACACAACAATGGTGGTGATAAAGGTAACCTAACAAATGGTCCTG
AACTTCAAGACGACCTTTTTGTTGGTGCTGCTCTTGGTGTTGAATTAACACCATGGTTAGGTTTTGAAGCTGAATATAAC
CAAGTTAAAGGTGATGTTGATGGTGCTGCTGCTGGCGCTGAATACAAACAACAACAAATCAATGGTAACTTCTACGTTAC
TTCTGATTTGATCACTAAAAACTATGACAGCAAAATCAAGCCTTACGTATTGTTAGGTGCTGGTCACTATAAGTATGACT
TTGACGGTGTAGACCGTGGTTACCGTGGTAACAAAGAAGAAGGTACTCTTGGTAACGCGGGTATCGGTGCTTTCTGGCGT
TTGAATGATGCATTGTCTCTTCGTACAGAAGCGCGTGCAACTTATAACGCTGATGAAGAGTTCTGGAACTACACAGCACT
TGCTGGTCTAAACGTTGTTCTTGGCGGTCACTTGAAGCCTGCTGCTCCAGTAGTAGAAGTTGCTCCAGTTGAGCCTGCTC
CAGTTGTTCAACCTCAGCAACCACAAGAGTTGACTGAAGATTTGAACATGGAATTGCGTGTATTCTTTGATACAAACAAA
TCAAACATCAAAGACCAATACAAACCAGAAATTGCAAAAGTTGCTGAAAAATTGGTTGAATATCCAAATGCAACTGCTCG
CATCGATGGTCACACAGACAACACTGGTCCACGTAAGTTGAACGAACGTTTGTCATTGGCTCGTGCTAACTCTGTTAAGT
CTGCACTTGTAAATGAATACAACATCGATCCAGCTCGTTTGGCTACTCAAGGTTTTGCATGGGATCAACCAATTGCTGAC
AACAGCACTAAAGAAGGTCGTGCAATGAACCGTCGTGTATTCGCTACAATCACTGGTAGCCGTACAGTAACAGTTCAACC
TGGTCAACAAGCTCCTGCTGCTCAATAA

Upstream 100 bases:

>100_bases
TAAAAAAAAAACTGGGGTACAAAAAGCTTATCTCAGGAAGCCAAAAAAATTTTAGGCTGAGCTTGAACAACAAACAATTT
GTTATCTCTGGAGGATATCC

Downstream 100 bases:

>100_bases
TTTGAGTTTGATCAGATAAAAAAAAGCAGCTCTTCGGAGCTGCTTTTTTATTTGTGCTAAAATTTTCATGTTTTATTCCT
TCATTTAAATCTATTGATCA

Product: Outer membrane protein precursor (OmpA-like)

Products: NA

Alternate protein names: Outer membrane protein ompA; Outer membrane protein ompAb [H]

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDSQHNNGGDKGNLTNGPELQDDLFVGAALGVELTPWLGFEAEYN
QVKGDVDGAAAGAEYKQQQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYDFDGVDRGYRGNKEEGTLGNAGIGAFWR
LNDALSLRTEARATYNADEEFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPAPVVQPQQPQELTEDLNMELRVFFDTNK
SNIKDQYKPEIAKVAEKLVEYPNATARIDGHTDNTGPRKLNERLSLARANSVKSALVNEYNIDPARLATQGFAWDQPIAD
NSTKEGRAMNRRVFATITGSRTVTVQPGQQAPAAQ

Sequences:

>Translated_355_residues
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDSQHNNGGDKGNLTNGPELQDDLFVGAALGVELTPWLGFEAEYN
QVKGDVDGAAAGAEYKQQQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYDFDGVDRGYRGNKEEGTLGNAGIGAFWR
LNDALSLRTEARATYNADEEFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPAPVVQPQQPQELTEDLNMELRVFFDTNK
SNIKDQYKPEIAKVAEKLVEYPNATARIDGHTDNTGPRKLNERLSLARANSVKSALVNEYNIDPARLATQGFAWDQPIAD
NSTKEGRAMNRRVFATITGSRTVTVQPGQQAPAAQ
>Mature_355_residues
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDSQHNNGGDKGNLTNGPELQDDLFVGAALGVELTPWLGFEAEYN
QVKGDVDGAAAGAEYKQQQINGNFYVTSDLITKNYDSKIKPYVLLGAGHYKYDFDGVDRGYRGNKEEGTLGNAGIGAFWR
LNDALSLRTEARATYNADEEFWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPAPVVQPQQPQELTEDLNMELRVFFDTNK
SNIKDQYKPEIAKVAEKLVEYPNATARIDGHTDNTGPRKLNERLSLARANSVKSALVNEYNIDPARLATQGFAWDQPIAD
NSTKEGRAMNRRVFATITGSRTVTVQPGQQAPAAQ

Specific function: Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochr

COG id: COG2885

COG function: function code M; Outer membrane protein and related peptidoglycan-associated (lipo)proteins

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

Organism=Escherichia coli, GI48994946, Length=111, Percent_Identity=44.1441441441441, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788957, Length=112, Percent_Identity=40.1785714285714, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 38528; Mature: 38528

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDSQHNNGGDKGNLTNGPELQDDLF
CCCHHHHHHHHHHHHHHHHCCCCCEEEHEEEEEEECCCCCCCCCCCCCCCCCCCCCHHEE
VGAALGVELTPWLGFEAEYNQVKGDVDGAAAGAEYKQQQINGNFYVTSDLITKNYDSKIK
EEEECCEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCC
PYVLLGAGHYKYDFDGVDRGYRGNKEEGTLGNAGIGAFWRLNDALSLRTEARATYNADEE
CEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHH
FWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPAPVVQPQQPQELTEDLNMELRVFFDTNK
HHCCHHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCEEEEEEECCC
SNIKDQYKPEIAKVAEKLVEYPNATARIDGHTDNTGPRKLNERLSLARANSVKSALVNEY
CCCCHHHCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NIDPARLATQGFAWDQPIADNSTKEGRAMNRRVFATITGSRTVTVQPGQQAPAAQ
CCCHHHHHHCCCCCCCCCCCCCCCCCHHCCCEEEEEEECCEEEEECCCCCCCCCC
>Mature Secondary Structure
MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDSQHNNGGDKGNLTNGPELQDDLF
CCCHHHHHHHHHHHHHHHHCCCCCEEEHEEEEEEECCCCCCCCCCCCCCCCCCCCCHHEE
VGAALGVELTPWLGFEAEYNQVKGDVDGAAAGAEYKQQQINGNFYVTSDLITKNYDSKIK
EEEECCEEECCCCCCCCHHHHHCCCCCCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCC
PYVLLGAGHYKYDFDGVDRGYRGNKEEGTLGNAGIGAFWRLNDALSLRTEARATYNADEE
CEEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCCCCHH
FWNYTALAGLNVVLGGHLKPAAPVVEVAPVEPAPVVQPQQPQELTEDLNMELRVFFDTNK
HHCCHHHHCCEEEECCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHCCCCEEEEEEECCC
SNIKDQYKPEIAKVAEKLVEYPNATARIDGHTDNTGPRKLNERLSLARANSVKSALVNEY
CCCCHHHCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NIDPARLATQGFAWDQPIADNSTKEGRAMNRRVFATITGSRTVTVQPGQQAPAAQ
CCCHHHHHHCCCCCCCCCCCCCCCCCHHCCCEEEEEEECCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA