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The map label for this gene is uppP1

Identifier: 50083906

GI number: 50083906

Start: 670954

End: 671778

Strand: Direct

Name: uppP1

Synonym: ACIAD0678

Alternate gene names: 50083906

Gene position: 670954-671778 (Clockwise)

Preceding gene: 50083905

Following gene: 50083907

Centisome position: 18.64

GC content: 41.09

Gene sequence:

>825_bases
ATGGATCTTTTACTGCTGTTAAAAGCAGCAATTATGGGTATTGTTGAAGGGATTACAGAGTTTCTTCCAATTTCGAGTAC
GGGCCACTTGATTCTGGCTTCTGAGCTGATGAATTTCTGGACAAAAGAAAAAAGTGCTGTGTTTGTCGTCGCGATTCAGA
TGGGAGCCATTGCAGCCGTTATTTATGAGTATTGGTCAAGATTGTGGGGTGCTGCCACAGGCATGGTAACAGGAGAAGAA
AAGGGACGTCATCTGGCAATCTCTCTCATTCTTGCATCTATTCCAATTGTGTTGGTGGGCTTAAGTTTTGGTCAAACAGT
CAAGGATTTACTTTTTAATGACGTCGCTGTGGCGATTGGTCTGATTGTTGGTGGCGTTATTATTATGTGGATTGAGAAAA
ATCCACCTAAAGTAAATGCGGTCGAAGTTGAAAATATTGGTCTAAAACAAGCCATCTGGATTGGCTTAATCCAAGTTTTA
TCCTTGATTCCAGGAACATCACGTTCTGGTGCAACCATTATTGGGGCTATGTTTTTGGGGGTATCTCGTAAAGCTGCGAC
CGAATTTTCATTCTTTTTAGGTATACCTGTGATTATTGGTGCAGGCTTACTGGATCTGTATCAAAGCCATGAAGTATTAC
AAACCAGTTTTGACTGGAGTGTATTGGGCGTTGGAATTCTGGTTTCTTTTGTTTCTGCTTTACTACTCATTCGTGCATTG
GTTGCCTATGTTGCAAAACGTGATTTCATGGTTTTTGCGTGGTATCGCATAGTATCTGGTCTGCTCATTTTACTCTTTGC
TTATACGGGTTGGACAATATGGTAA

Upstream 100 bases:

>100_bases
TCAGCAATGGGTTTCAGCCGAGCATGCCCTTCCAGTTTATTTACGTGATAACGCATGGAAGAAAATTTCAGAACAGGGTA
AAGCATAATTAGGATACTTT

Downstream 100 bases:

>100_bases
AACCGATGCATCTATTTGCTGTGGTTGATGCTCTGGAGCAAGCACAACAATTTCAACAGGTGCTTGCCTCCCGAGATGTG
AGCACCGAACTGGTACAGAT

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein 1; Undecaprenyl pyrophosphate phosphatase 1

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MDLLLLLKAAIMGIVEGITEFLPISSTGHLILASELMNFWTKEKSAVFVVAIQMGAIAAVIYEYWSRLWGAATGMVTGEE
KGRHLAISLILASIPIVLVGLSFGQTVKDLLFNDVAVAIGLIVGGVIIMWIEKNPPKVNAVEVENIGLKQAIWIGLIQVL
SLIPGTSRSGATIIGAMFLGVSRKAATEFSFFLGIPVIIGAGLLDLYQSHEVLQTSFDWSVLGVGILVSFVSALLLIRAL
VAYVAKRDFMVFAWYRIVSGLLILLFAYTGWTIW

Sequences:

>Translated_274_residues
MDLLLLLKAAIMGIVEGITEFLPISSTGHLILASELMNFWTKEKSAVFVVAIQMGAIAAVIYEYWSRLWGAATGMVTGEE
KGRHLAISLILASIPIVLVGLSFGQTVKDLLFNDVAVAIGLIVGGVIIMWIEKNPPKVNAVEVENIGLKQAIWIGLIQVL
SLIPGTSRSGATIIGAMFLGVSRKAATEFSFFLGIPVIIGAGLLDLYQSHEVLQTSFDWSVLGVGILVSFVSALLLIRAL
VAYVAKRDFMVFAWYRIVSGLLILLFAYTGWTIW
>Mature_274_residues
MDLLLLLKAAIMGIVEGITEFLPISSTGHLILASELMNFWTKEKSAVFVVAIQMGAIAAVIYEYWSRLWGAATGMVTGEE
KGRHLAISLILASIPIVLVGLSFGQTVKDLLFNDVAVAIGLIVGGVIIMWIEKNPPKVNAVEVENIGLKQAIWIGLIQVL
SLIPGTSRSGATIIGAMFLGVSRKAATEFSFFLGIPVIIGAGLLDLYQSHEVLQTSFDWSVLGVGILVSFVSALLLIRAL
VAYVAKRDFMVFAWYRIVSGLLILLFAYTGWTIW

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=264, Percent_Identity=43.1818181818182, Blast_Score=191, Evalue=4e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP1_ACIAD (Q6FEB4)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045416.1
- STRING:   Q6FEB4
- GeneID:   2881078
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0678
- NMPDR:   fig|62977.3.peg.373
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   VATIPVM
- PhylomeDB:   Q6FEB4
- ProtClustDB:   PRK00281
- BioCyc:   ASP62977:ACIAD0678-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29699; Mature: 29699

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15d5971c)-; HASH(0x16928774)-; HASH(0x14f52ae0)-; HASH(0x16a60a88)-; HASH(0x14f44150)-; HASH(0x14db4d8c)-; HASH(0x14ecdbdc)-; HASH(0x1590fef0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLLLLKAAIMGIVEGITEFLPISSTGHLILASELMNFWTKEKSAVFVVAIQMGAIAAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHH
IYEYWSRLWGAATGMVTGEEKGRHLAISLILASIPIVLVGLSFGQTVKDLLFNDVAVAIG
HHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LIVGGVIIMWIEKNPPKVNAVEVENIGLKQAIWIGLIQVLSLIPGTSRSGATIIGAMFLG
HHHHHHEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VSRKAATEFSFFLGIPVIIGAGLLDLYQSHEVLQTSFDWSVLGVGILVSFVSALLLIRAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VAYVAKRDFMVFAWYRIVSGLLILLFAYTGWTIW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCH
>Mature Secondary Structure
MDLLLLLKAAIMGIVEGITEFLPISSTGHLILASELMNFWTKEKSAVFVVAIQMGAIAAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEHHHHHHHH
IYEYWSRLWGAATGMVTGEEKGRHLAISLILASIPIVLVGLSFGQTVKDLLFNDVAVAIG
HHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LIVGGVIIMWIEKNPPKVNAVEVENIGLKQAIWIGLIQVLSLIPGTSRSGATIIGAMFLG
HHHHHHEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VSRKAATEFSFFLGIPVIIGAGLLDLYQSHEVLQTSFDWSVLGVGILVSFVSALLLIRAL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
VAYVAKRDFMVFAWYRIVSGLLILLFAYTGWTIW
HHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA