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The map label for this gene is pabB [H]

Identifier: 50083894

GI number: 50083894

Start: 658717

End: 660027

Strand: Reverse

Name: pabB [H]

Synonym: ACIAD0665

Alternate gene names: 50083894

Gene position: 660027-658717 (Counterclockwise)

Preceding gene: 50083902

Following gene: 50083886

Centisome position: 18.34

GC content: 35.93

Gene sequence:

>1311_bases
ATGCTCCTTCAACAGTCTGAAGTGACTGGATTAGTTTTTTTGAATAATAAGGATCAGCCGATTATCGGATTTAATCCTGC
TACATTTTGTATTTTTCAAGATCATCAACTTCATTACTACAAAAGAGATGAATCAAATCAATATATCGAGGATCAAGATA
ATACCGAGCTGACTGAATTTATCATTTTTCAGAATTCTGAATATTCTACAAAAAGTATAAATAGTAAATTTCAGGGTGGT
TATATTGGATTCATTGGCTATGATTATGCTGCATCACAATATGTAAATACCGATTTCTGTGTACAACCTGCGCTTTATGT
AGGCAAATATCTGAGTTACCTGACTCAAGAAAATGACGAATGGTATTTTTATAGTCAATCTCCAAATGCTGAAACTGAAT
ATTTACAACTACTTAGTATTTTCACCCAACAAATTTCTGAGAATAACTCAAGCTTCTATATATCAACACCATTTCAATCC
CGATGGACAAAATCGACATATTTAAAGGCTTTTGAAAAAATTCAGGATTACATCAAATCAGGGGATTGTTATCAAATTAA
TTTGACACAAGAATTTCAAACGCACTGCAAAGGAAATTTACTTTCAAAAGCCGATCAACTTTGGGATTTAACCAATGCTC
CTTACGCAGGTTATTTGCAGATAGGTGATTTTGAATTACTCAGTTGTTCGCCTGAGTTATTTATCGAATTTAATGAGTAT
CGACAAATCAAGACACGTCCTATTAAAGGAACTATGCCGCGTTTTGATAATGCCGAGTTAGATCAAATGTCTAAACAAAA
ATTACAAGCATCAGAAAAAGATCAGGCAGAAAATGTCATGATTGTCGATCTGTTACGTAATGATCTAAGTGTCTATGCAG
AAGTTGGCTCAGTAAAAACAACAAAACTTTTTGAAATTGAAAGCTTCAATCAGGTTCATCATATGGTCAGTGAAATCACG
GCCACGCTCAAAGCTGATGTTAATCCTTTTGAGGTCTTACTCACTGCTTTACCAGGTGGTTCGATTACTGGTGCTCCCAA
GATTCGAGCCATGCAGATTATAGATGAGCTTGAAGGCGAGCCACGTGGGGCTTATTGCGGTTCTTTAGGTTACTTTAATT
TTGATGGTACAGGTTGCTGGAATATTTTAATTCGTAGTCTGCAACGGTATCAAGATCAACTTTCTTTATGGGCAGGTGGT
GGCATTACCATCGCATCAAACTCTGAGGCTGAATATCAGGAATGTTTTGATAAAGTCTCTGCCATGCTGAATCTAATCAA
TACATGGCAAAGCATGCAAAGCACGGCTTAA

Upstream 100 bases:

>100_bases
AGTAAAATTACTCGCTATTTTTTCGTTCATACTTGAGCAACTTCTCGTGCAGTATATTCAAAAACTCCCTCTTCCAGCTC
AATCAGCCCAGCATATTCTA

Downstream 100 bases:

>100_bases
TTAATAAATAGTTTTAAAGTATTTACTAAGCGCTGATTCTGCTCGTCTGTGCCTACAGTAATTCTTAGATATTGATTGAT
ACGTGGTTTATTGAAATGAC

Product: p-aminobenzoate synthetase

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MLLQQSEVTGLVFLNNKDQPIIGFNPATFCIFQDHQLHYYKRDESNQYIEDQDNTELTEFIIFQNSEYSTKSINSKFQGG
YIGFIGYDYAASQYVNTDFCVQPALYVGKYLSYLTQENDEWYFYSQSPNAETEYLQLLSIFTQQISENNSSFYISTPFQS
RWTKSTYLKAFEKIQDYIKSGDCYQINLTQEFQTHCKGNLLSKADQLWDLTNAPYAGYLQIGDFELLSCSPELFIEFNEY
RQIKTRPIKGTMPRFDNAELDQMSKQKLQASEKDQAENVMIVDLLRNDLSVYAEVGSVKTTKLFEIESFNQVHHMVSEIT
ATLKADVNPFEVLLTALPGGSITGAPKIRAMQIIDELEGEPRGAYCGSLGYFNFDGTGCWNILIRSLQRYQDQLSLWAGG
GITIASNSEAEYQECFDKVSAMLNLINTWQSMQSTA

Sequences:

>Translated_436_residues
MLLQQSEVTGLVFLNNKDQPIIGFNPATFCIFQDHQLHYYKRDESNQYIEDQDNTELTEFIIFQNSEYSTKSINSKFQGG
YIGFIGYDYAASQYVNTDFCVQPALYVGKYLSYLTQENDEWYFYSQSPNAETEYLQLLSIFTQQISENNSSFYISTPFQS
RWTKSTYLKAFEKIQDYIKSGDCYQINLTQEFQTHCKGNLLSKADQLWDLTNAPYAGYLQIGDFELLSCSPELFIEFNEY
RQIKTRPIKGTMPRFDNAELDQMSKQKLQASEKDQAENVMIVDLLRNDLSVYAEVGSVKTTKLFEIESFNQVHHMVSEIT
ATLKADVNPFEVLLTALPGGSITGAPKIRAMQIIDELEGEPRGAYCGSLGYFNFDGTGCWNILIRSLQRYQDQLSLWAGG
GITIASNSEAEYQECFDKVSAMLNLINTWQSMQSTA
>Mature_436_residues
MLLQQSEVTGLVFLNNKDQPIIGFNPATFCIFQDHQLHYYKRDESNQYIEDQDNTELTEFIIFQNSEYSTKSINSKFQGG
YIGFIGYDYAASQYVNTDFCVQPALYVGKYLSYLTQENDEWYFYSQSPNAETEYLQLLSIFTQQISENNSSFYISTPFQS
RWTKSTYLKAFEKIQDYIKSGDCYQINLTQEFQTHCKGNLLSKADQLWDLTNAPYAGYLQIGDFELLSCSPELFIEFNEY
RQIKTRPIKGTMPRFDNAELDQMSKQKLQASEKDQAENVMIVDLLRNDLSVYAEVGSVKTTKLFEIESFNQVHHMVSEIT
ATLKADVNPFEVLLTALPGGSITGAPKIRAMQIIDELEGEPRGAYCGSLGYFNFDGTGCWNILIRSLQRYQDQLSLWAGG
GITIASNSEAEYQECFDKVSAMLNLINTWQSMQSTA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=355, Percent_Identity=41.9718309859155, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1787518, Length=358, Percent_Identity=28.2122905027933, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786809, Length=200, Percent_Identity=27.5, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=265, Percent_Identity=33.5849056603774, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=309, Percent_Identity=29.4498381877023, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 49881; Mature: 49881

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLQQSEVTGLVFLNNKDQPIIGFNPATFCIFQDHQLHYYKRDESNQYIEDQDNTELTEF
CCCCCCCCCEEEEECCCCCCEEECCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCEEEE
IIFQNSEYSTKSINSKFQGGYIGFIGYDYAASQYVNTDFCVQPALYVGKYLSYLTQENDE
EEEECCCCCCHHCCCCCCCCEEEEEECCHHHHHHCCCCHHHCHHHHHHHHHHHHHCCCCC
WYFYSQSPNAETEYLQLLSIFTQQISENNSSFYISTPFQSRWTKSTYLKAFEKIQDYIKS
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHC
GDCYQINLTQEFQTHCKGNLLSKADQLWDLTNAPYAGYLQIGDFELLSCSPELFIEFNEY
CCEEEEEECHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCEEEEECCHHHEEEECCC
RQIKTRPIKGTMPRFDNAELDQMSKQKLQASEKDQAENVMIVDLLRNDLSVYAEVGSVKT
CCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEE
TKLFEIESFNQVHHMVSEITATLKADVNPFEVLLTALPGGSITGAPKIRAMQIIDELEGE
EEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCC
PRGAYCGSLGYFNFDGTGCWNILIRSLQRYQDQLSLWAGGGITIASNSEAEYQECFDKVS
CCCCEECCCCEECCCCCCHHHHHHHHHHHHHHHHHEEECCCEEEECCCCHHHHHHHHHHH
AMLNLINTWQSMQSTA
HHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLLQQSEVTGLVFLNNKDQPIIGFNPATFCIFQDHQLHYYKRDESNQYIEDQDNTELTEF
CCCCCCCCCEEEEECCCCCCEEECCCEEEEEEECCEEEEEECCCCCCCCCCCCCCCEEEE
IIFQNSEYSTKSINSKFQGGYIGFIGYDYAASQYVNTDFCVQPALYVGKYLSYLTQENDE
EEEECCCCCCHHCCCCCCCCEEEEEECCHHHHHHCCCCHHHCHHHHHHHHHHHHHCCCCC
WYFYSQSPNAETEYLQLLSIFTQQISENNSSFYISTPFQSRWTKSTYLKAFEKIQDYIKS
EEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHCCHHHHHHHHHHHHHHHHC
GDCYQINLTQEFQTHCKGNLLSKADQLWDLTNAPYAGYLQIGDFELLSCSPELFIEFNEY
CCEEEEEECHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEECCEEEEECCHHHEEEECCC
RQIKTRPIKGTMPRFDNAELDQMSKQKLQASEKDQAENVMIVDLLRNDLSVYAEVGSVKT
CCEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHCCCEE
TKLFEIESFNQVHHMVSEITATLKADVNPFEVLLTALPGGSITGAPKIRAMQIIDELEGE
EEEEEEHHHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCHHHHHHHHHHCCC
PRGAYCGSLGYFNFDGTGCWNILIRSLQRYQDQLSLWAGGGITIASNSEAEYQECFDKVS
CCCCEECCCCEECCCCCCHHHHHHHHHHHHHHHHHEEECCCEEEECCCCHHHHHHHHHHH
AMLNLINTWQSMQSTA
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]