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The map label for this gene is pgpB [C]

Identifier: 50083791

GI number: 50083791

Start: 547718

End: 548272

Strand: Direct

Name: pgpB [C]

Synonym: ACIAD0554

Alternate gene names: 50083791

Gene position: 547718-548272 (Clockwise)

Preceding gene: 50083790

Following gene: 50083792

Centisome position: 15.22

GC content: 41.62

Gene sequence:

>555_bases
ATGATGAATTTTAAAAATGCGAAAATAAGAATGCTTGACCTTGATTTGAGAGGTTGTGTTTACCTGAATCATTTTTCACA
CTCTCAGCGAGTCGCCTGGTTTTTTAAAGGAATCAGCCGTTTGGGCGATGGTTTTTTTTGGTATGTCATGTTGGCATTGG
TCTGGATCAATCAGGGTTTGATGTATGGCTTACAAATCCTGTATTTGGTAGTGGGTGGTTCAGTTGGAACAGGTATTTAT
AAGTTTCTCAAAAACAAGACCACTCGACCTCGGCCTTATCAGGTGCATCAAGTAATTGTGTTGGGTGAGCGACCATTGGA
TCATTTTAGTTTTCCTTCAGGTCATACGCTACATGCAGTCATGGCAACCATTACATTAGGTTACGTCCAACCGATATTGG
TTGTTTTGATGTTGCCATTTACTTTACTGGTTGCACTGTCCCGGATGATTTTGGGGCTACATTACCCAAGTGATGTTCTG
GTTGGTGCATTTATTGGTGCAATTGTAGCCTGTGGAATCGTATTCTGTGCGCCATTGGCGGGCATTGTTCTTTAA

Upstream 100 bases:

>100_bases
TGGCAGTATCCCGTACAACAAATGGAACAGGCCTTATATCGGGTGGTAAAGGAGCCCTACATGAAATGAATCTAAGCGCA
AGGCGTGAGGAGTAGTAAAC

Downstream 100 bases:

>100_bases
TAAAGACATTCTCTCGGTTTTAGAAATTTGTTAGAGTAGCTTTAAGTTAAATCATGAAACAGGAAGTAAGAATGGGCTTA
CGTTGGACAGATACAATAGA

Product: phosphatidylglycerophosphatase B (PgpB)

Products: Phospatidylglycerol; Phosphate [C]

Alternate protein names: Phosphoesterase PA-Phosphatase Related Protein; Membrane-Associated Phospholipid Phosphatase; PAP2 Superfamily Protein; Phosphatidylglycerophosphatase B; Phospholipid Phosphatase; Phosphoesterase Family Protein; Phosphoesterase; PA-Phosphatase-Like Phosphoesterase; Phosphoesterase PA-Phosphatase-Like Protein; PAP2 Family Protein; Phosphoesterase Phosphatidic Acid Phosphatase-Related; Transmembrane PAP Family Protein; Phosphoesterase Pa-Phosphatase

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MMNFKNAKIRMLDLDLRGCVYLNHFSHSQRVAWFFKGISRLGDGFFWYVMLALVWINQGLMYGLQILYLVVGGSVGTGIY
KFLKNKTTRPRPYQVHQVIVLGERPLDHFSFPSGHTLHAVMATITLGYVQPILVVLMLPFTLLVALSRMILGLHYPSDVL
VGAFIGAIVACGIVFCAPLAGIVL

Sequences:

>Translated_184_residues
MMNFKNAKIRMLDLDLRGCVYLNHFSHSQRVAWFFKGISRLGDGFFWYVMLALVWINQGLMYGLQILYLVVGGSVGTGIY
KFLKNKTTRPRPYQVHQVIVLGERPLDHFSFPSGHTLHAVMATITLGYVQPILVVLMLPFTLLVALSRMILGLHYPSDVL
VGAFIGAIVACGIVFCAPLAGIVL
>Mature_184_residues
MMNFKNAKIRMLDLDLRGCVYLNHFSHSQRVAWFFKGISRLGDGFFWYVMLALVWINQGLMYGLQILYLVVGGSVGTGIY
KFLKNKTTRPRPYQVHQVIVLGERPLDHFSFPSGHTLHAVMATITLGYVQPILVVLMLPFTLLVALSRMILGLHYPSDVL
VGAFIGAIVACGIVFCAPLAGIVL

Specific function: Hydrolyzes Phosphatidylglycerophosphate, Phosphatidic Acid, And Lysophosphatidic Acid; The Pattern Of Activities Varies According To Subcellular Location. [C]

COG id: COG0671

COG function: function code I; Membrane-associated phospholipid phosphatase

Gene ontology:

Cell location: Integral Membrane Protein. Inner And Outer Membranes [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Caenorhabditis elegans, GI25147418, Length=82, Percent_Identity=41.4634146341463, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.3.27 [C]

Molecular weight: Translated: 20529; Mature: 20529

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNFKNAKIRMLDLDLRGCVYLNHFSHSQRVAWFFKGISRLGDGFFWYVMLALVWINQGL
CCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
MYGLQILYLVVGGSVGTGIYKFLKNKTTRPRPYQVHQVIVLGERPLDHFSFPSGHTLHAV
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHH
MATITLGYVQPILVVLMLPFTLLVALSRMILGLHYPSDVLVGAFIGAIVACGIVFCAPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIVL
HHCC
>Mature Secondary Structure
MMNFKNAKIRMLDLDLRGCVYLNHFSHSQRVAWFFKGISRLGDGFFWYVMLALVWINQGL
CCCCCCCEEEEEEECCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
MYGLQILYLVVGGSVGTGIYKFLKNKTTRPRPYQVHQVIVLGERPLDHFSFPSGHTLHAV
HHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHH
MATITLGYVQPILVVLMLPFTLLVALSRMILGLHYPSDVLVGAFIGAIVACGIVFCAPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
GIVL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O; Phosphatidylglycerophosphate [C]

Specific reaction: H2O + (0.02) Phosphatidylglycerophosphate --> (0.02) Phospatidylglycerol + Phosphate [C]

General reaction: Phosphoric ester hydrolysis [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA