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The map label for this gene is yggV [C]

Identifier: 50083764

GI number: 50083764

Start: 511425

End: 512096

Strand: Reverse

Name: yggV [C]

Synonym: ACIAD0526

Alternate gene names: 50083764

Gene position: 512096-511425 (Counterclockwise)

Preceding gene: 50083765

Following gene: 50083761

Centisome position: 14.23

GC content: 43.15

Gene sequence:

>672_bases
TTGTTTTTTAGTTTTTCTCTTTTTACTCGAGTTTTAATTATGTCTGCACCACATTGGCTCTCTCAAGGCACACTCGTCTT
AGCCAGCAACAACAAAGGTAAAATTACCGAATTTGAAAAGTTATTTGCCGAGCTTCAGCTTCCTGTCGATGTCATTCCTC
AAGGCCAACTGAACATCCCAGATGCCATTGAGGACGGTTTAAGCTTTGTTGAAAATGCCATTATTAAAGCACGGCATGCC
TCTAAAATTTCAGGGAAACCTGCGATTGCCGATGATTCAGGAATTTGTGTTCCTGTATTGGGCGGTGCTCCAGGAATCTA
TTCTGCACGTTATGCAGGTGATCATGGCAATGATGCTGCCAATAATGAGAAACTTCTGCATGACTTAAAGCCGTTCCGTA
ATGCTGAACAAGCGATTCAAGGCATGTTTGTATGCGTACTCGCCTTAGTCGAGCATGCCGAAGATCCTCTGCCGCAAATT
TTCCAAGGATTTTGGCATGGCGAAATTTTGGAACAAGCACGTGGTGAACATGGCTTTGGTTATGATCCATTATTTTGGTT
GTCTGAACTAAAAATGAGCAGTGCGGAAATGAGCAAGGAAGAAAAGAATAAAATCAGCCATCGTGGACAGGCGATGCAGC
GCTTTCGTGAGAGTTTGATGACTAGAGAGTGA

Upstream 100 bases:

>100_bases
AACTTGACCCAAGATCAGATTCGTCAAGCGGTTGATCGTGCGGATAAATGGATTCAGGCGCAGTAAGTTTTTTGAATTTT
AAAGCACCTTCGGGTGCTTT

Downstream 100 bases:

>100_bases
ATAAGTTAAATAAAATTAGATACGCGAAAACGTCGTTCGCAACTGTTCGAGACAAACCACTATCTGCAATATATTGTTTC
TGCGATATATTATTATGTAA

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MFFSFSLFTRVLIMSAPHWLSQGTLVLASNNKGKITEFEKLFAELQLPVDVIPQGQLNIPDAIEDGLSFVENAIIKARHA
SKISGKPAIADDSGICVPVLGGAPGIYSARYAGDHGNDAANNEKLLHDLKPFRNAEQAIQGMFVCVLALVEHAEDPLPQI
FQGFWHGEILEQARGEHGFGYDPLFWLSELKMSSAEMSKEEKNKISHRGQAMQRFRESLMTRE

Sequences:

>Translated_223_residues
MFFSFSLFTRVLIMSAPHWLSQGTLVLASNNKGKITEFEKLFAELQLPVDVIPQGQLNIPDAIEDGLSFVENAIIKARHA
SKISGKPAIADDSGICVPVLGGAPGIYSARYAGDHGNDAANNEKLLHDLKPFRNAEQAIQGMFVCVLALVEHAEDPLPQI
FQGFWHGEILEQARGEHGFGYDPLFWLSELKMSSAEMSKEEKNKISHRGQAMQRFRESLMTRE
>Mature_223_residues
MFFSFSLFTRVLIMSAPHWLSQGTLVLASNNKGKITEFEKLFAELQLPVDVIPQGQLNIPDAIEDGLSFVENAIIKARHA
SKISGKPAIADDSGICVPVLGGAPGIYSARYAGDHGNDAANNEKLLHDLKPFRNAEQAIQGMFVCVLALVEHAEDPLPQI
FQGFWHGEILEQARGEHGFGYDPLFWLSELKMSSAEMSKEEKNKISHRGQAMQRFRESLMTRE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=47.1794871794872, Blast_Score=187, Evalue=4e-49,
Organism=Drosophila melanogaster, GI19920712, Length=147, Percent_Identity=32.6530612244898, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 24768; Mature: 24768

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFSFSLFTRVLIMSAPHWLSQGTLVLASNNKGKITEFEKLFAELQLPVDVIPQGQLNIP
CCCCHHHHHHHHHHHCCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCHHCCCCCCCCCC
DAIEDGLSFVENAIIKARHASKISGKPAIADDSGICVPVLGGAPGIYSARYAGDHGNDAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
NNEKLLHDLKPFRNAEQAIQGMFVCVLALVEHAEDPLPQIFQGFWHGEILEQARGEHGFG
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC
YDPLFWLSELKMSSAEMSKEEKNKISHRGQAMQRFRESLMTRE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFFSFSLFTRVLIMSAPHWLSQGTLVLASNNKGKITEFEKLFAELQLPVDVIPQGQLNIP
CCCCHHHHHHHHHHHCCHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCHHCCCCCCCCCC
DAIEDGLSFVENAIIKARHASKISGKPAIADDSGICVPVLGGAPGIYSARYAGDHGNDAA
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
NNEKLLHDLKPFRNAEQAIQGMFVCVLALVEHAEDPLPQIFQGFWHGEILEQARGEHGFG
CHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCC
YDPLFWLSELKMSSAEMSKEEKNKISHRGQAMQRFRESLMTRE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA