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The map label for this gene is exbB [H]

Identifier: 50083746

GI number: 50083746

Start: 498945

End: 499568

Strand: Direct

Name: exbB [H]

Synonym: ACIAD0508

Alternate gene names: 50083746

Gene position: 498945-499568 (Clockwise)

Preceding gene: 50083745

Following gene: 50083747

Centisome position: 13.86

GC content: 42.31

Gene sequence:

>624_bases
ATGAACTTTTCAGTTTATTGGCAACATGCAGATGCAGTCAGCAAAACACTGTACTTCGTGCTTTTGGCAATGTCGATTGC
AACATGGACAATTTTCATCTTACGTTTGATGGGAACACGCCAATTAAAACAACAAGCTTATGCTCAACTATCTAAAGCAT
TATCAAGCTTGAAAGCAAAGTTTACACATCTCACATTTGAACAACGTAAGGCAGTTGCAGAACAAGCTTTACTTCGTCAG
ATTTCTGCTGAAAAATCAAATGCAGAAAAGGGTGTAGCAGTATTAGGAACTATTGCTTCGATTGCACCATTTGTCGGCTT
ATTTGGAACGGTATGGGGTATTTTCCATGCGCTGGTTGCAGTCGGTAAAAGTGGTCAGGCTGGTTTGGCACAAGTGGCAA
CTCCTGTAGGCGAAGCACTGATCATGACAGGTTTGGGTCTGGCTGTTGCAATTCCTGCGGTATTGGCTTACAACATTTGT
GTACGTTTTAATCGTGGCTTGGCGCATGATCTTCAAGATCAGGCACATAGCTTATTGATTGATACCATGTTGCAGCAAGA
ATCTGTAGATCCAAAATCTGAAACGAAGGCAGCGCAACAAAGCTATGCTGGAGGTCAAGCTTAA

Upstream 100 bases:

>100_bases
AAACCGTATAAAGAAAATGGTGTGGCTTATCCGATTCGTGCAGAGCAACCTTTTGACCTAACATTAAATCCTAACGGCTA
ACATTTTCAGGAGTTCGAGT

Downstream 100 bases:

>100_bases
TGGCTTTTCAACTGGGTGAAGACCACGACAGTGGCATGAATGAGATGAATCTCATTCCGTTAATTGACATTATGTTGGTA
CTGATGATCATCTTTTTGGT

Product: biopolymer transport protein (ExbB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MNFSVYWQHADAVSKTLYFVLLAMSIATWTIFILRLMGTRQLKQQAYAQLSKALSSLKAKFTHLTFEQRKAVAEQALLRQ
ISAEKSNAEKGVAVLGTIASIAPFVGLFGTVWGIFHALVAVGKSGQAGLAQVATPVGEALIMTGLGLAVAIPAVLAYNIC
VRFNRGLAHDLQDQAHSLLIDTMLQQESVDPKSETKAAQQSYAGGQA

Sequences:

>Translated_207_residues
MNFSVYWQHADAVSKTLYFVLLAMSIATWTIFILRLMGTRQLKQQAYAQLSKALSSLKAKFTHLTFEQRKAVAEQALLRQ
ISAEKSNAEKGVAVLGTIASIAPFVGLFGTVWGIFHALVAVGKSGQAGLAQVATPVGEALIMTGLGLAVAIPAVLAYNIC
VRFNRGLAHDLQDQAHSLLIDTMLQQESVDPKSETKAAQQSYAGGQA
>Mature_207_residues
MNFSVYWQHADAVSKTLYFVLLAMSIATWTIFILRLMGTRQLKQQAYAQLSKALSSLKAKFTHLTFEQRKAVAEQALLRQ
ISAEKSNAEKGVAVLGTIASIAPFVGLFGTVWGIFHALVAVGKSGQAGLAQVATPVGEALIMTGLGLAVAIPAVLAYNIC
VRFNRGLAHDLQDQAHSLLIDTMLQQESVDPKSETKAAQQSYAGGQA

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1786958, Length=193, Percent_Identity=34.7150259067358, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789381, Length=239, Percent_Identity=31.3807531380753, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 22234; Mature: 22234

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFSVYWQHADAVSKTLYFVLLAMSIATWTIFILRLMGTRQLKQQAYAQLSKALSSLKAK
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTHLTFEQRKAVAEQALLRQISAEKSNAEKGVAVLGTIASIAPFVGLFGTVWGIFHALVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGKSGQAGLAQVATPVGEALIMTGLGLAVAIPAVLAYNICVRFNRGLAHDLQDQAHSLLI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DTMLQQESVDPKSETKAAQQSYAGGQA
HHHHHHHCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNFSVYWQHADAVSKTLYFVLLAMSIATWTIFILRLMGTRQLKQQAYAQLSKALSSLKAK
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTHLTFEQRKAVAEQALLRQISAEKSNAEKGVAVLGTIASIAPFVGLFGTVWGIFHALVA
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGKSGQAGLAQVATPVGEALIMTGLGLAVAIPAVLAYNICVRFNRGLAHDLQDQAHSLLI
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
DTMLQQESVDPKSETKAAQQSYAGGQA
HHHHHHHCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9140974 [H]