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The map label for this gene is ecpD [H]

Identifier: 50083647

GI number: 50083647

Start: 381485

End: 382192

Strand: Direct

Name: ecpD [H]

Synonym: ACIAD0388

Alternate gene names: 50083647

Gene position: 381485-382192 (Clockwise)

Preceding gene: 50083646

Following gene: 50083648

Centisome position: 10.6

GC content: 37.57

Gene sequence:

>708_bases
ATGCGTAAGTTCAGTTTTATTATTTCGATATTGTTACTTAGTCAGTATACAAATGCTGGTGTCAGCATAGATGGTACTCG
CATTATTTTTCCTTCCAATGCTAAAAGTGTTAGTGTGCAATTACGTAATGGATTTGCTACACCGGCGTTGGTACAAACCT
GGATTGATCAGGGTGATATGAGCAGTATTCCTGCAGCTGATCAAATTCCTTTTGTACTCACGCCACCTTTATCGCGTGTT
GAGGCTAAAAAAGGACAAATCATTCGTATCATACCTACAGGTTCTCCTGCTTTACCGCAGGATCGCGAGTCCTTGTACTG
GTTTAATATGTTGGATATTCCACCTGAAGATTCGGCAAATAAAGATAAAAATATACTCACTTTTAATGTACGTAGCCGTA
TTAAACTGTTTTATCGTCCAACAGGCTTAAAAATGTCCTCCGATAAGGCATTTGCTAGTGTTGGTTATAGCTACAATAAC
GGCACTCAAGCTGTCACTTTAAATAATCCGACGCCTTATTTTGTCACAGTGACCAAAGTAGATTTTAAAAATCAAAGTCA
AACAGCAAGCTATAACGCAGATGTAGTCATGCTAGCGCCCTTTTCACAACAAATATTGAATAAGTTTCAGTTGAAGTTTA
AGCCTGATCAAATGAACTATACAATTATTAATGATTTAGGCGGCAACCAGACTTTTGAGATGAAATAA

Upstream 100 bases:

>100_bases
AATATTACTCAACCACAGCAACGCCAGCTGCTCAACAAGTAAATTCTGTTGTTAATTATATTTTAAACTATAATTAATCT
TTTTGAGTACGAGGAAAAAT

Downstream 100 bases:

>100_bases
AGAAACACTCATTGAGTATTTAACGGTATGAAAATCAGATATTCGAGTAGTTTTTTACTGCTTATTCTTCTTGTAAGCAA
GTCTTATGCTGCTTCCGAAT

Product: fimbrial chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MRKFSFIISILLLSQYTNAGVSIDGTRIIFPSNAKSVSVQLRNGFATPALVQTWIDQGDMSSIPAADQIPFVLTPPLSRV
EAKKGQIIRIIPTGSPALPQDRESLYWFNMLDIPPEDSANKDKNILTFNVRSRIKLFYRPTGLKMSSDKAFASVGYSYNN
GTQAVTLNNPTPYFVTVTKVDFKNQSQTASYNADVVMLAPFSQQILNKFQLKFKPDQMNYTIINDLGGNQTFEMK

Sequences:

>Translated_235_residues
MRKFSFIISILLLSQYTNAGVSIDGTRIIFPSNAKSVSVQLRNGFATPALVQTWIDQGDMSSIPAADQIPFVLTPPLSRV
EAKKGQIIRIIPTGSPALPQDRESLYWFNMLDIPPEDSANKDKNILTFNVRSRIKLFYRPTGLKMSSDKAFASVGYSYNN
GTQAVTLNNPTPYFVTVTKVDFKNQSQTASYNADVVMLAPFSQQILNKFQLKFKPDQMNYTIINDLGGNQTFEMK
>Mature_235_residues
MRKFSFIISILLLSQYTNAGVSIDGTRIIFPSNAKSVSVQLRNGFATPALVQTWIDQGDMSSIPAADQIPFVLTPPLSRV
EAKKGQIIRIIPTGSPALPQDRESLYWFNMLDIPPEDSANKDKNILTFNVRSRIKLFYRPTGLKMSSDKAFASVGYSYNN
GTQAVTLNNPTPYFVTVTKVDFKNQSQTASYNADVVMLAPFSQQILNKFQLKFKPDQMNYTIINDLGGNQTFEMK

Specific function: Probably mediates assembly of a pilin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786333, Length=227, Percent_Identity=39.2070484581498, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1788428, Length=232, Percent_Identity=35.7758620689655, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790771, Length=184, Percent_Identity=33.1521739130435, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789532, Length=239, Percent_Identity=29.7071129707113, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1786936, Length=199, Percent_Identity=33.6683417085427, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786743, Length=184, Percent_Identity=34.2391304347826, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788677, Length=181, Percent_Identity=35.3591160220994, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787171, Length=221, Percent_Identity=30.316742081448, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI87081806, Length=225, Percent_Identity=28.8888888888889, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082203, Length=219, Percent_Identity=31.0502283105023, Blast_Score=79, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 26293; Mature: 26293

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS00635 PILI_CHAPERONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKFSFIISILLLSQYTNAGVSIDGTRIIFPSNAKSVSVQLRNGFATPALVQTWIDQGDM
CCHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCC
SSIPAADQIPFVLTPPLSRVEAKKGQIIRIIPTGSPALPQDRESLYWFNMLDIPPEDSAN
CCCCCCCCCCEEECCCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCC
KDKNILTFNVRSRIKLFYRPTGLKMSSDKAFASVGYSYNNGTQAVTLNNPTPYFVTVTKV
CCCCEEEEEECCEEEEEECCCCCEECCCCCEEEECEEECCCEEEEEECCCCCEEEEEEEE
DFKNQSQTASYNADVVMLAPFSQQILNKFQLKFKPDQMNYTIINDLGGNQTFEMK
ECCCCCCCCCCCCCEEEECCCHHHHHHHHEEEECCCCCCEEEEEECCCCEEEEEC
>Mature Secondary Structure
MRKFSFIISILLLSQYTNAGVSIDGTRIIFPSNAKSVSVQLRNGFATPALVQTWIDQGDM
CCHHHHHHHHHHHHHHCCCCEEECCCEEEECCCCCEEEEEEECCCCCHHHHHHHHCCCCC
SSIPAADQIPFVLTPPLSRVEAKKGQIIRIIPTGSPALPQDRESLYWFNMLDIPPEDSAN
CCCCCCCCCCEEECCCHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCC
KDKNILTFNVRSRIKLFYRPTGLKMSSDKAFASVGYSYNNGTQAVTLNNPTPYFVTVTKV
CCCCEEEEEECCEEEEEECCCCCEECCCCCEEEECEEECCCEEEEEECCCCCEEEEEEEE
DFKNQSQTASYNADVVMLAPFSQQILNKFQLKFKPDQMNYTIINDLGGNQTFEMK
ECCCCCCCCCCCCCEEEECCCHHHHHHHHEEEECCCCCCEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102362; 8202364; 9278503 [H]