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The map label for this gene is lpxO

Identifier: 50083603

GI number: 50083603

Start: 334122

End: 335036

Strand: Direct

Name: lpxO

Synonym: ACIAD0337

Alternate gene names: NA

Gene position: 334122-335036 (Clockwise)

Preceding gene: 50083602

Following gene: 50083604

Centisome position: 9.28

GC content: 38.91

Gene sequence:

>915_bases
ATGATTAAGTGGATCATATTAGCGATTTTTGTGATATCAGCCTTGTATATCCAGCATCGCGGCAAAGTTCGTCATTCGTT
TTATCGTCAGTTCTTTGATCATTCGACGTTACTTGCGCCCATCAATTTTCTGATGTACATGTTTTCAAAAGTGCCTAATC
AGCCTTATATTGAAACTCAACATTTCAAGGATTTGAAAATACTGGATGAAAATTGGGAAATGATTCGCGATGAAGCCAGA
GCATTGTATGATCAGGGCGGGATCAAGGCTTCAAGTACTTATAACGATCTTGGTTTCAATTCATTTTTTAAAACTGGCTG
GAAACGATTTTATCTAAAATGGTACGACTCTGCGCATCCTTCTGCGGCTGAGCTCTGTCCAAAAACAACGGCACTATTAA
AAACATTGCCATCTATTAAGGCGGCGATGTTTACCGAGCTTGCACCCAATAGTCGTCTGGTTCGTCATCGTGATCCTTAT
GCAGGTTCATTACGCTATCATTTGGGTTTGATCACGCCCAATGATGATCGTTGCTTTATCGATGTAGATGGACAGCGTTA
TTCATGGCGTGATGGGGAAAGTGTGGTGTTTGATGAAACGTATATTCATTATGCTGAAAATACCACAGACCAAAACCGGA
TTATTTTCTTTGCTGACGTTGAACGTCCTTTAAAAACAAGGCTTATGGAAAAGTTTAACCACTGGTTTGGTAAAAATGTA
ATGACGGCTGCAAGTTCTCCAAACGAGACAGGTGATAAAACTGGTGGTCTTAATAAAGCCTTTGGTTATATTTATCAGAT
TCGTATCAAAGCCAAAGCATTAAAAGCCAAAAACCGTAAACTGTATTACTTCTTGAAGTGGTTTCTCATGCTTGGAATCT
TTTTCCTGATTTTTGTACGTCCTTATGTGTTTTAA

Upstream 100 bases:

>100_bases
GCTAATACTAAGTCTGAATTTTCTTCGAGATTTTGTTATTATTCCTTCAATTTCAAATTTTTTGAAGTATCTTTAAATAT
GCTTAAATGCGAGTAACTAT

Downstream 100 bases:

>100_bases
AATTTAAACGCCCAATAGGGCGTTTTTTTTTGAGATGTAAAAAAGCATAATAGGGTGTAGATGTGATGTGTATCACGTTG
TTTTAAATTTGTTACAACTA

Product: beta-hydroxylase

Products: NA

Alternate protein names: Beta-Hydroxylase; Membrane-Bound Beta-Hydroxylase; Aspartyl/Asparaginyl Beta-Hydroxylase Family Protein; Aspartyl-Asparaginyl Beta-Hydroxylase; Asparaginyl Beta-Hydroxylase; Aspartyl/Asparaginyl Beta-Hydroxylase Family; Lipopolysaccharide Biosynthetic; Peptide-Aspartate Beta-Dioxygenase; Hydroxylase; Lipid A-Myristate Beta-Hydroxylase; Peptide-Aspartate B-Dioxygenase; Aspartate Beta-Hydroxylase; Aspartyl/Asparaginyl Beta-Hydroxylase Transmembrane Protein; Beta-Hydroxylase Aspartyl/Asparaginyl Family; Lipopolysaccharide Biosynthetic Protein; Fe(2+)/Alpha-Ketoglutarate-Dependent Dioxygenase LpxO; Peptide Aspartate B-Dioxygenase; Dioxygenase; Aspartyl/Asparaginyl Beta-Hydroxylase Protein; Aspartyl/Asparaginyl-Beta-Hydroxylase

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MIKWIILAIFVISALYIQHRGKVRHSFYRQFFDHSTLLAPINFLMYMFSKVPNQPYIETQHFKDLKILDENWEMIRDEAR
ALYDQGGIKASSTYNDLGFNSFFKTGWKRFYLKWYDSAHPSAAELCPKTTALLKTLPSIKAAMFTELAPNSRLVRHRDPY
AGSLRYHLGLITPNDDRCFIDVDGQRYSWRDGESVVFDETYIHYAENTTDQNRIIFFADVERPLKTRLMEKFNHWFGKNV
MTAASSPNETGDKTGGLNKAFGYIYQIRIKAKALKAKNRKLYYFLKWFLMLGIFFLIFVRPYVF

Sequences:

>Translated_304_residues
MIKWIILAIFVISALYIQHRGKVRHSFYRQFFDHSTLLAPINFLMYMFSKVPNQPYIETQHFKDLKILDENWEMIRDEAR
ALYDQGGIKASSTYNDLGFNSFFKTGWKRFYLKWYDSAHPSAAELCPKTTALLKTLPSIKAAMFTELAPNSRLVRHRDPY
AGSLRYHLGLITPNDDRCFIDVDGQRYSWRDGESVVFDETYIHYAENTTDQNRIIFFADVERPLKTRLMEKFNHWFGKNV
MTAASSPNETGDKTGGLNKAFGYIYQIRIKAKALKAKNRKLYYFLKWFLMLGIFFLIFVRPYVF
>Mature_304_residues
MIKWIILAIFVISALYIQHRGKVRHSFYRQFFDHSTLLAPINFLMYMFSKVPNQPYIETQHFKDLKILDENWEMIRDEAR
ALYDQGGIKASSTYNDLGFNSFFKTGWKRFYLKWYDSAHPSAAELCPKTTALLKTLPSIKAAMFTELAPNSRLVRHRDPY
AGSLRYHLGLITPNDDRCFIDVDGQRYSWRDGESVVFDETYIHYAENTTDQNRIIFFADVERPLKTRLMEKFNHWFGKNV
MTAASSPNETGDKTGGLNKAFGYIYQIRIKAKALKAKNRKLYYFLKWFLMLGIFFLIFVRPYVF

Specific function: Unknown

COG id: COG3555

COG function: function code O; Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194328779, Length=189, Percent_Identity=27.5132275132275, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI14589866, Length=187, Percent_Identity=27.807486631016, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI258613943, Length=187, Percent_Identity=27.807486631016, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 35817; Mature: 35817

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKWIILAIFVISALYIQHRGKVRHSFYRQFFDHSTLLAPINFLMYMFSKVPNQPYIETQ
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HFKDLKILDENWEMIRDEARALYDQGGIKASSTYNDLGFNSFFKTGWKRFYLKWYDSAHP
CCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCC
SAAELCPKTTALLKTLPSIKAAMFTELAPNSRLVRHRDPYAGSLRYHLGLITPNDDRCFI
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEEEECCCCEEEE
DVDGQRYSWRDGESVVFDETYIHYAENTTDQNRIIFFADVERPLKTRLMEKFNHWFGKNV
EECCCEECCCCCCEEEEECCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCE
MTAASSPNETGDKTGGLNKAFGYIYQIRIKAKALKAKNRKLYYFLKWFLMLGIFFLIFVR
EECCCCCCCCCCCCCCCHHHHHEEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PYVF
HHCC
>Mature Secondary Structure
MIKWIILAIFVISALYIQHRGKVRHSFYRQFFDHSTLLAPINFLMYMFSKVPNQPYIETQ
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCC
HFKDLKILDENWEMIRDEARALYDQGGIKASSTYNDLGFNSFFKTGWKRFYLKWYDSAHP
CCCCCEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCC
SAAELCPKTTALLKTLPSIKAAMFTELAPNSRLVRHRDPYAGSLRYHLGLITPNDDRCFI
CHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCEEEEEEEEECCCCEEEE
DVDGQRYSWRDGESVVFDETYIHYAENTTDQNRIIFFADVERPLKTRLMEKFNHWFGKNV
EECCCEECCCCCCEEEEECCEEEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHCCCE
MTAASSPNETGDKTGGLNKAFGYIYQIRIKAKALKAKNRKLYYFLKWFLMLGIFFLIFVR
EECCCCCCCCCCCCCCCHHHHHEEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
PYVF
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA